Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis

Platelets have distinct roles in the vascular system in that they are the major mediator of thrombosis, critical for restoration of tissue integrity, and players in vascular inflammatory conditions. In close spatiotemporal proximity, the complement system acts as the first line of defense against in...

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Vydáno v:	Circulation (New York, N.Y.) Ročník 138; číslo 16; s. 1720
Hlavní autoři:	Sauter, Reinhard J, Sauter, Manuela, Reis, Edimara S, Emschermann, Frederic N, Nording, Henry, Ebenhöch, Sonja, Kraft, Peter, Münzer, Patrick, Mauler, Maximilian, Rheinlaender, Johannes, Madlung, Johannes, Edlich, Frank, Schäffer, Tilman E, Meuth, Sven G, Dürschmied, Daniel, Geisler, Tobias, Borst, Oliver, Gawaz, Meinrad, Kleinschnitz, Christoph, Lambris, John D, Langer, Harald F
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 16.10.2018
Témata:	blood platelets complement system proteins thrombosis inflammation anaphylatoxins myocardial infarction stroke
ISSN:	1524-4539, 1524-4539
On-line přístup:	Zjistit podrobnosti o přístupu
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