Mesenchymal Stem Cells: Characteristics, Function, and Application

[...]novel strategies for maintaining, and even promoting, the biological activities and therapeutic capabilities of MSCs are really needed. J. Zhan et al. reported that fasudil, a potent rho kinase inhibitor, significantly enhanced the migration ability of bone marrow MSCs via activation of the MAP...

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Vydáno v:Stem cells international Ročník 2019; s. 1 - 2
Hlavní autoři: Li, Zhongjun, Hu, Xingbin, Zhong, Jiang F.
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Hindawi 01.01.2019
John Wiley & Sons, Inc
Wiley
Témata:
Bone marrow
Enzyme inhibitors
Homing
Homing behavior
Kinases
MAP kinase
Medicine
Mesenchymal stem cells
Mesenchyme
Migration
Protein expression
Proteins
Rho-associated kinase
Signal transduction
Spinal cord injuries
Stem cells
ISSN:1687-966X, 1687-9678, 1687-9678
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Shrnutí:[...]novel strategies for maintaining, and even promoting, the biological activities and therapeutic capabilities of MSCs are really needed. J. Zhan et al. reported that fasudil, a potent rho kinase inhibitor, significantly enhanced the migration ability of bone marrow MSCs via activation of the MAPK signaling pathway, promoting MSC homing to the spinal cord injury site. [...]we would like to express our deep gratitude to the reviewers for their valuable contributions to this special issue.
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ISSN:1687-966X
1687-9678
1687-9678
DOI:10.1155/2019/8106818