Direct coupling analysis and the attention mechanism

Proteins are involved in nearly all cellular functions, encompassing roles in transport, signaling, enzymatic activity, and more. Their functionalities crucially depend on their complex three-dimensional arrangement. For this reason, being able to predict their structure from the amino acid sequence...

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Bibliographic Details
Published in:	BMC bioinformatics Vol. 26; no. 1; pp. 41 - 21
Main Authors:	Caredda, Francesco, Pagnani, Andrea
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 06.02.2025 Springer Nature B.V BMC
Subjects:	Accuracy Algorithms Amino acid sequence Amino acids Architecture Attention mechanism Cellular structure Complexity Computational Biology - methods Computational linguistics Coupling Direct coupling analysis Enzymatic activity Enzymes Evolution Information processing Language processing Machine learning Methods Models, Molecular Natural language interfaces Protein Conformation Protein families Protein Folding Protein structure Protein structure prediction Protein transport Proteins Proteins - chemistry Structure-function relationships Terminology Transformer Italy Attention mechanism Direct coupling analysis Protein structure prediction Transformer
ISSN:	1471-2105, 1471-2105
Online Access:	Get full text
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