A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells

Actin is abundant in the nuclei of oocytes but its role has been unclear. Feric and Brangwynne find that actin forms a network that prevents the sedimentation of RNA and protein bodies caused by gravitational forces. The size of a typical eukaryotic cell is of the order of ∼10 μm. However, some cell...

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