Sex-specific Estrogen Levels and Reference Intervals from Infancy to Late Adulthood Determined by LC-MS/MS

Abstract Context The lack of sensitive and robust analytical methods has hindered the reliable quantification of estrogen metabolites in subjects with low concentrations. Objective To establish sex-specific reference ranges for estrone (E1) and estradiol (E2) throughout life and to evaluate sex-diff...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism Jg. 105; H. 3; S. 754 - 768
Hauptverfasser:	Frederiksen, Hanne, Johannsen, Trine Holm, Andersen, Stine Ehlern, Albrethsen, Jakob, Landersoe, Selma Kløve, Petersen, Jørgen Holm, Andersen, Anders Nyboe, Vestergaard, Esben Thyssen, Schorring, Mia Elbek, Linneberg, Allan, Main, Katharina M, Andersson, Anna-Maria, Juul, Anders
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	US Oxford University Press 01.03.2020
Schlagworte:	17β-Estradiol Age Breast Children Clinical s Estrogen Estrone Human physical development Liquid chromatography Mass spectrometry Mass spectroscopy Menstrual cycle Metabolites Physiological research Post-menopause Puberty Testing Denmark estrone LC-MS/MS mini-puberty childhood menopause menstrual cycle pubertal development reference range estradiol
ISSN:	0021-972X, 1945-7197, 1945-7197
Online-Zugang:	Volltext
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