Modulation of the chromatin phosphoproteome by the Haspin protein kinase

Recent discoveries have highlighted the importance of Haspin kinase activity for the correct positioning of the kinase Aurora B at the centromere. Haspin phosphorylates Thr(3) of the histone H3 (H3), which provides a signal for Aurora B to localize to the centromere of mitotic chromosomes. To date,...

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Veröffentlicht in:	Molecular & cellular proteomics Jg. 13; H. 7; S. 1724
Hauptverfasser:	Maiolica, Alessio, de Medina-Redondo, Maria, Schoof, Erwin M, Chaikuad, Apirat, Villa, Fabrizio, Gatti, Marco, Jeganathan, Siva, Lou, Hua Jane, Novy, Karel, Hauri, Simon, Toprak, Umut H, Herzog, Franz, Meraldi, Patrick, Penengo, Lorenza, Turk, Benjamin E, Knapp, Stefan, Linding, Rune, Aebersold, Ruedi
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.2014
Schlagworte:	Amino Acid Sequence Aurora Kinase B - metabolism Cell Line, Tumor Chromatin - genetics Chromatin - metabolism Gene Expression Regulation - genetics HEK293 Cells HeLa Cells Histones - genetics Histones - metabolism Humans Intracellular Signaling Peptides and Proteins - antagonists & inhibitors Intracellular Signaling Peptides and Proteins - metabolism Methylation Mitosis - genetics Nuclear Proteins - metabolism Phosphoproteins - metabolism Phosphorylation Protein Interaction Maps - genetics Protein Serine-Threonine Kinases - antagonists & inhibitors Protein Serine-Threonine Kinases - metabolism RNA-Binding Proteins - metabolism Serine-Arginine Splicing Factors Transcription, Genetic - genetics
ISSN:	1535-9484, 1535-9484
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