Unconventional post-translational modifications in immunological signaling

Immune system proteins are subject to numerous post-translational modifications. In this Focus Review, Mowen and David describe the key 'non-conventional' modifications such as acetylation and nitrosylation that affect immunologically-relevant proteins. The activity of a cell is governed b...

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Bibliographic Details
Published in:	Nature immunology Vol. 15; no. 6; pp. 512 - 520
Main Authors:	Mowen, Kerri A, David, Michael
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.06.2014 Nature Publishing Group
Subjects:	631/250/516 Acetylation Acetyltransferases - immunology Animals Biomedicine Cell Differentiation - immunology Cellular signal transduction Genetic aspects Health aspects Humans Hydrolases - genetics Hydrolases - immunology Immune response Immune system Immune System - immunology Immunology Infectious Diseases Methylation Methyltransferases - immunology Mice Phosphorylation Physiological aspects Post-translational modification Protein Processing, Post-Translational - genetics Protein Processing, Post-Translational - immunology Protein-Arginine Deiminases Protein-Arginine N-Methyltransferases - genetics Protein-Arginine N-Methyltransferases - immunology Receptor, Interferon alpha-beta - immunology Residues review-article Signal Transduction - immunology
ISSN:	1529-2908, 1529-2916, 1529-2916
Online Access:	Get full text
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