THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to...

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Veröffentlicht in:	British journal of pharmacology Jg. 178; H. S1; S. S27 - S156
Hauptverfasser:	Alexander, Stephen PH, Davenport, Anthony P, Peters, John A, Veale, Emma L, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria Pia, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne, Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo, Castaño, Justo P., Ceruti, Stefania, Chazot, Paul, Chini, Bice, Cianciulli, Antonia, Couture, Réjean, Dent, Gordon, Douglas, Steven D., Eguchi, Satoru, Escher, Emanuel, Fong, Tung, Gasparo, Marc de, Gerard, Craig, Gershengorn, Marvin, Gobeil, Fernand, Goodfriend, Theodore L., Gregory, Karen J., Gundlach, Andrew L., Hamann, Jörg, Hanson, Julien, Hauger, Richard L., Hay, Debbie L., Heinemann, Akos, Hollenberg, Morley D., Holliday, Nicholas D., Horiuchi, Mastgugu, Husain, Ahsan, Jacobson, Kenneth A., Jensen, Robert T., Jockers, Ralf, Jonnalagadda, Deepa, Karnik, Sadashiva, Kennedy, Charles, Kitazawa, Takio, Kozielewicz, Pawel, Kreienkamp, Hans‐Jürgen, Leeman, Susan E., Leprince, Jérôme, Li, Xaria X., Williams, Tom Lloyd, Macrae, Robyn, Maguire, Janet, McArdle, Craig A., Melmed, Shlomo, Mitolo, Vincenzo, Müller, Christa E., Murphy, Philip, Nahon, Jean‐Louis, Norel, Xavier, Nyimanu, Duuamene, Pertwee, Roger G., Pin, Jean‐Philippe, Prossnitz, Eric R., Quinn, Mark, Ramachandran, Rithwik, Rondard, Philippe, Ruzza, Chiara, Sanger, Gareth J., Schöneberg, Torsten, Schulz, Stefan, Segaloff, Deborah L., Serhan, Charles N., Stoddart, Leigh A., Summers, Roger, Tan, Valerie P., Thal, David, Thomas, Walter (Wally), Timmermans, Pieter B. M. W. M., Tulipano, Giovanni, Unal, Hamiyet, Unger, Thomas, Vanderheyden, Patrick, Vaudry, David, Vaudry, Hubert, Walker, Christopher S., Ward, Donald T., Ye, Richard D.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Blackwell Publishing Ltd 01.10.2021 Wiley Wiley-Blackwell
Schlagworte:	Basic Medicine Biochemistry, biophysics & molecular biology Biochimie, biophysique & biologie moléculaire Databases, Pharmaceutical Human health sciences Humans Ion Channels Life Sciences Ligands Medicinska och farmaceutiska grundvetenskaper Nuclear receptors Pharmacie, pharmacologie & toxicologie Pharmacology Pharmacy, pharmacology & toxicology Receptors, Cytoplasmic and Nuclear Receptors, G-Protein-Coupled Sciences de la santé humaine Sciences du vivant Therapeutic targets
ISSN:	0007-1188, 1476-5381, 1476-5381
Online-Zugang:	Volltext
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Zusammenfassung:	The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
Bibliographie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 scopus-id:2-s2.0-85115083018
ISSN:	0007-1188 1476-5381 1476-5381
DOI:	10.1111/bph.15538