Interleukin-10 blocks atherosclerotic events in vitro and in vivo

Atherosclerosis can be viewed in part as an inflammatory disease process and may therefore be susceptible to manipulation of the immune state. Interleukin 10 (IL-10) is an inhibitory cytokine produced by activated lymphocytes and monocytes. These studies present evidence that IL-10 can inhibit minim...

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Bibliographic Details
Published in:	Arteriosclerosis, thrombosis, and vascular biology Vol. 19; no. 12; p. 2847
Main Authors:	Pinderski Oslund, L J, Hedrick, C C, Olvera, T, Hagenbaugh, A, Territo, M, Berliner, J A, Fyfe, A I
Format:	Journal Article
Language:	English
Published:	United States 01.12.1999
Subjects:	Adenoviridae - genetics Animals Aorta - cytology Arteriosclerosis - drug therapy Arteriosclerosis - immunology Arteriosclerosis - pathology Cell Adhesion - drug effects Cell Adhesion - immunology Cells, Cultured Disease Models, Animal Endothelium, Vascular - cytology Endothelium, Vascular - immunology Endothelium, Vascular - pathology Gene Expression Regulation, Viral Humans In Vitro Techniques Interleukin-10 - genetics Interleukin-10 - immunology Interleukin-10 - pharmacology Lipoproteins - metabolism Mice Mice, Inbred C57BL Mice, Knockout Monocytes - cytology Monocytes - immunology Oxidation-Reduction Phospholipid Ethers - pharmacology
ISSN:	1079-5642
Online Access:	Get more information
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