Susceptibility of SARS-CoV-2 to UV irradiation

•SARS-CoV-2 is highly susceptible to irradiation with ultraviolet light.•High viral loads of 5 * 106 TCID50/ml SARS-CoV-2 can be inactivated in 9 minutes by UVC irradiation.•UVC irradiation represents a suitable disinfection method for SARS-CoV-2. The coronavirus SARS-CoV-2 pandemic became a global...

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Vydáno v:American journal of infection control Ročník 48; číslo 10; s. 1273 - 1275
Hlavní autoři: Heilingloh, Christiane Silke, Aufderhorst, Ulrich Wilhelm, Schipper, Leonie, Dittmer, Ulf, Witzke, Oliver, Yang, Dongliang, Zheng, Xin, Sutter, Kathrin, Trilling, Mirko, Alt, Mira, Steinmann, Eike, Krawczyk, Adalbert
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Elsevier Inc 01.10.2020
Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc
Témata:
Betacoronavirus - radiation effects
Brief Report
Coronavirus Infections - virology
COVID-19
Disinfection - methods
Humans
Inactivation
Infectious Disease
Pandemics
Pneumonia, Viral - virology
SARS-CoV-2
Ultraviolet light
Ultraviolet Rays
Virus Inactivation - radiation effects
COVID-19
Inactivation
Ultraviolet light
ISSN:0196-6553, 1527-3296, 1527-3296
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Shrnutí:•SARS-CoV-2 is highly susceptible to irradiation with ultraviolet light.•High viral loads of 5 * 106 TCID50/ml SARS-CoV-2 can be inactivated in 9 minutes by UVC irradiation.•UVC irradiation represents a suitable disinfection method for SARS-CoV-2. The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 106 TCID50/mL was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1,048 mJ/cm2. UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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These authors share senior authorship.
ISSN:0196-6553
1527-3296
1527-3296
DOI:10.1016/j.ajic.2020.07.031