A cost-effective sequencing method for genetic studies combining high-depth whole exome and low-depth whole genome

Whole genome sequencing (WGS) at high-depth (30X) allows the accurate discovery of variants in the coding and non-coding DNA regions and helps elucidate the genetic underpinnings of human health and diseases. Yet, due to the prohibitive cost of high-depth WGS, most large-scale genetic association st...

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Vydáno v:	Npj genomic medicine Ročník 9; číslo 1; s. 8 - 12
Hlavní autoři:	Bhérer, Claude, Eveleigh, Robert, Trajanoska, Katerina, St-Cyr, Janick, Paccard, Antoine, Nadukkalam Ravindran, Praveen, Caron, Elizabeth, Bader Asbah, Nimara, McClelland, Peyton, Wei, Clare, Baumgartner, Iris, Schindewolf, Marc, Döring, Yvonne, Perley, Danielle, Lefebvre, François, Lepage, Pierre, Bourgey, Mathieu, Bourque, Guillaume, Ragoussis, Jiannis, Mooser, Vincent, Taliun, Daniel
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 07.02.2024 Nature Publishing Group Nature Portfolio
Témata:	631/1647/514/2254 631/208/514/1948 Bioinformatics Biomedical and Life Sciences Biomedicine Disease Gene Function Gene Therapy Genomes Genotypes Genotyping Human Genetics Internal Medicine Vascular diseases Whole genome sequencing
ISSN:	2056-7944, 2056-7944
On-line přístup:	Získat plný text
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