Inflammatory and neurodegenerative serum protein biomarkers increase sensitivity to detect clinical and radiographic disease activity in multiple sclerosis

The multifaceted nature of multiple sclerosis requires quantitative biomarkers that can provide insights related to diverse physiological pathways. To this end, proteomic analysis of deeply-phenotyped serum samples, biological pathway modeling, and network analysis were performed to elucidate inflam...

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Vydané v:Nature communications Ročník 15; číslo 1; s. 4297 - 12
Hlavní autori: Chitnis, Tanuja, Qureshi, Ferhan, Gehman, Victor M., Becich, Michael, Bove, Riley, Cree, Bruce A. C., Gomez, Refujia, Hauser, Stephen L., Henry, Roland G., Katrib, Amal, Lokhande, Hrishikesh, Paul, Anu, Caillier, Stacy J., Santaniello, Adam, Sattarnezhad, Neda, Saxena, Shrishti, Weiner, Howard, Yano, Hajime, Baranzini, Sergio E.
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: London Nature Publishing Group UK 20.05.2024
Nature Publishing Group
Nature Portfolio
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ISSN:2041-1723, 2041-1723
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