Exposure to a mixture of non-persistent environmental chemicals and neonatal thyroid function in a cohort with improved exposure assessment

In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with improved exposure assessment (i.e., repeated urine samples) are needed to evaluate effects of these compounds, individually or as a mixture,...

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Published in:	Environment international Vol. 173; p. 107840
Main Authors:	Coiffier, Ophélie, Nakiwala, Dorothy, Rolland, Matthieu, Malatesta, Andres, Lyon-Caen, Sarah, Chovelon, Benoît, Faure, Patrice, Sophie Gauchez, Anne, Guergour, Dorra, Sakhi, Amrit K., Sabaredzovic, Azemira, Thomsen, Cathrine, Pin, Isabelle, Slama, Rémy, Corne, Christelle, Philippat, Claire
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.03.2023 Elsevier
Subjects:	Bayes Theorem Bayesian theory benzophenones Bisphenols blood serum children DINCH environment Environmental Exposure - adverse effects Environmental Pollutants - urine Environmental Sciences exposure assessment Female Heel-prick blood spot homeostasis Hormones Humans Infant, Newborn iodine Male maternal exposure metabolites Mixture Parabens Parabens - analysis Phthalates Phthalic Acids - toxicity Phthalic Acids - urine Pregnancy Prenatal Exposure Delayed Effects regression analysis selenium thyroid function Thyroid Gland Thyroid Hormones Thyrotropin thyroxine triclosan Triclosan - toxicity urine MEHP oxo-MINCH DiNP MMCHP Heel-prick blood spot Mixture MBzP oxo-MiNP Bisphenols ΣDiNP DEHP OH-MPHP Thyroid hormones ΣDINCH T3 WHO LOD T4 MEOHP MEHHP TSH MnBP Oh-MINCH Phthalates DINCH DEP MiBP Parabens LOQ Oh-MiNP BKMR ΣDEHP MECPP MEP cx-MiNP
ISSN:	0160-4120, 1873-6750, 1873-6750
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Abstract	In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with improved exposure assessment (i.e., repeated urine samples) are needed to evaluate effects of these compounds, individually or as a mixture, in humans. We studied the associations between prenatal exposure to non-persistent environmental chemicals and neonatal thyroid hormones. The study population consisted of 442 mother–child pairs from the French SEPAGES mother–child cohort recruited between July 2014 and July 2017. For each participant, four parabens, five bisphenols, triclosan, triclocarban, benzophenone-3 as well as metabolites of phthalates and of di(isononyl)cyclohexane-1,2-dicarboxylate were assessed in two pools of repeated urine samples (median: 21 spot urines per pool), collected in the 2nd and 3rd trimesters of pregnancy, respectively. Thyroid stimulating hormone (TSH) and total thyroxine (T4) levels were determined in newborns from a heel-prick blood spot. Maternal iodine and selenium were assessed in urine and serum, respectively. Adjusted linear regression (uni-pollutant model) and Bayesian Kernel Machine Regression (BKMR, mixture model) were applied to study overall and sex-stratified associations between chemicals and hormone concentrations. Interaction with child sex was detected for several compounds. Triclosan, three parabens, and one phthalate metabolite (OH-MPHP) were negatively associated with T4 among girls in the uni-pollutant model. BKMR also suggested a negative association between the mixture and T4 in girls, whereas in boys the association was positive. The mixture was not linked to TSH levels, and for this hormone the uni-pollutant model revealed associations with only a few compounds. Our study, based on repeated urine samples to assess exposure, showed that prenatal exposure to some phenols and phthalates disturb thyroid hormone homeostasis at birth. Furthermore, both uni-pollutant and mixture models, suggested effect modification by child sex, while, to date underlying mechanisms for such sex-differences are not well understood.
AbstractList	Background: In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with improved exposure assessment (i.e., repeated urine samples) are needed to evaluate effects of these compounds, individually or as a mixture, in humans. We studied the associations between prenatal exposure to non-persistent environmental chemicals and neonatal thyroid hormones.Methods: The study population consisted of 442 mother–child pairs from the French SEPAGES mother–child cohort recruited between July 2014 and July 2017. For each participant, four parabens, five bisphenols, tri- closan, triclocarban, benzophenone-3 as well as metabolites of phthalates and of di(isononyl)cyclohexane-1,2- dicarboxylate were assessed in two pools of repeated urine samples (median: 21 spot urines per pool), collected in the 2nd and 3rd trimesters of pregnancy, respectively. Thyroid stimulating hormone (TSH) and total thyroxine (T4) levels were determined in newborns from a heel-prick blood spot. Maternal iodine and selenium were assessed in urine and serum, respectively. Adjusted linear regression (uni-pollutant model) and Bayesian Kernel Machine Regression (BKMR, mixture model) were applied to study overall and sex-stratified associations between chemicals and hormone concentrations.Results: Interaction with child sex was detected for several compounds. Triclosan, three parabens, and one phthalate metabolite (OH-MPHP) were negatively associated with T4 among girls in the uni-pollutant model. BKMR also suggested a negative association between the mixture and T4 in girls, whereas in boys the association was positive. The mixture was not linked to TSH levels, and for this hormone the uni-pollutant model revealed associations with only a few compounds.Conclusion: Our study, based on repeated urine samples to assess exposure, showed that prenatal exposure to some phenols and phthalates disturb thyroid hormone homeostasis at birth. Furthermore, both uni-pollutant and mixture models, suggested effect modification by child sex, while, to date underlying mechanisms for such sex-differences are not well understood. In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with improved exposure assessment (i.e., repeated urine samples) are needed to evaluate effects of these compounds, individually or as a mixture, in humans. We studied the associations between prenatal exposure to non-persistent environmental chemicals and neonatal thyroid hormones.BACKGROUNDIn vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with improved exposure assessment (i.e., repeated urine samples) are needed to evaluate effects of these compounds, individually or as a mixture, in humans. We studied the associations between prenatal exposure to non-persistent environmental chemicals and neonatal thyroid hormones.The study population consisted of 442 mother-child pairs from the French SEPAGES mother-child cohort recruited between July 2014 and July 2017. For each participant, four parabens, five bisphenols, triclosan, triclocarban, benzophenone-3 as well as metabolites of phthalates and of di(isononyl)cyclohexane-1,2-dicarboxylate were assessed in two pools of repeated urine samples (median: 21 spot urines per pool), collected in the 2nd and 3rd trimesters of pregnancy, respectively. Thyroid stimulating hormone (TSH) and total thyroxine (T4) levels were determined in newborns from a heel-prick blood spot. Maternal iodine and selenium were assessed in urine and serum, respectively. Adjusted linear regression (uni-pollutant model) and Bayesian Kernel Machine Regression (BKMR, mixture model) were applied to study overall and sex-stratified associations between chemicals and hormone concentrations.METHODSThe study population consisted of 442 mother-child pairs from the French SEPAGES mother-child cohort recruited between July 2014 and July 2017. For each participant, four parabens, five bisphenols, triclosan, triclocarban, benzophenone-3 as well as metabolites of phthalates and of di(isononyl)cyclohexane-1,2-dicarboxylate were assessed in two pools of repeated urine samples (median: 21 spot urines per pool), collected in the 2nd and 3rd trimesters of pregnancy, respectively. Thyroid stimulating hormone (TSH) and total thyroxine (T4) levels were determined in newborns from a heel-prick blood spot. Maternal iodine and selenium were assessed in urine and serum, respectively. Adjusted linear regression (uni-pollutant model) and Bayesian Kernel Machine Regression (BKMR, mixture model) were applied to study overall and sex-stratified associations between chemicals and hormone concentrations.Interaction with child sex was detected for several compounds. Triclosan, three parabens, and one phthalate metabolite (OH-MPHP) were negatively associated with T4 among girls in the uni-pollutant model. BKMR also suggested a negative association between the mixture and T4 in girls, whereas in boys the association was positive. The mixture was not linked to TSH levels, and for this hormone the uni-pollutant model revealed associations with only a few compounds.RESULTSInteraction with child sex was detected for several compounds. Triclosan, three parabens, and one phthalate metabolite (OH-MPHP) were negatively associated with T4 among girls in the uni-pollutant model. BKMR also suggested a negative association between the mixture and T4 in girls, whereas in boys the association was positive. The mixture was not linked to TSH levels, and for this hormone the uni-pollutant model revealed associations with only a few compounds.Our study, based on repeated urine samples to assess exposure, showed that prenatal exposure to some phenols and phthalates disturb thyroid hormone homeostasis at birth. Furthermore, both uni-pollutant and mixture models, suggested effect modification by child sex, while, to date underlying mechanisms for such sex-differences are not well understood.CONCLUSIONOur study, based on repeated urine samples to assess exposure, showed that prenatal exposure to some phenols and phthalates disturb thyroid hormone homeostasis at birth. Furthermore, both uni-pollutant and mixture models, suggested effect modification by child sex, while, to date underlying mechanisms for such sex-differences are not well understood. In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with improved exposure assessment (i.e., repeated urine samples) are needed to evaluate effects of these compounds, individually or as a mixture, in humans. We studied the associations between prenatal exposure to non-persistent environmental chemicals and neonatal thyroid hormones. The study population consisted of 442 mother–child pairs from the French SEPAGES mother–child cohort recruited between July 2014 and July 2017. For each participant, four parabens, five bisphenols, triclosan, triclocarban, benzophenone-3 as well as metabolites of phthalates and of di(isononyl)cyclohexane-1,2-dicarboxylate were assessed in two pools of repeated urine samples (median: 21 spot urines per pool), collected in the 2nd and 3rd trimesters of pregnancy, respectively. Thyroid stimulating hormone (TSH) and total thyroxine (T4) levels were determined in newborns from a heel-prick blood spot. Maternal iodine and selenium were assessed in urine and serum, respectively. Adjusted linear regression (uni-pollutant model) and Bayesian Kernel Machine Regression (BKMR, mixture model) were applied to study overall and sex-stratified associations between chemicals and hormone concentrations. Interaction with child sex was detected for several compounds. Triclosan, three parabens, and one phthalate metabolite (OH-MPHP) were negatively associated with T4 among girls in the uni-pollutant model. BKMR also suggested a negative association between the mixture and T4 in girls, whereas in boys the association was positive. The mixture was not linked to TSH levels, and for this hormone the uni-pollutant model revealed associations with only a few compounds. Our study, based on repeated urine samples to assess exposure, showed that prenatal exposure to some phenols and phthalates disturb thyroid hormone homeostasis at birth. Furthermore, both uni-pollutant and mixture models, suggested effect modification by child sex, while, to date underlying mechanisms for such sex-differences are not well understood. In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with improved exposure assessment (i.e., repeated urine samples) are needed to evaluate effects of these compounds, individually or as a mixture, in humans. We studied the associations between prenatal exposure to non-persistent environmental chemicals and neonatal thyroid hormones. The study population consisted of 442 mother–child pairs from the French SEPAGES mother–child cohort recruited between July 2014 and July 2017. For each participant, four parabens, five bisphenols, triclosan, triclocarban, benzophenone-3 as well as metabolites of phthalates and of di(isononyl)cyclohexane-1,2-dicarboxylate were assessed in two pools of repeated urine samples (median: 21 spot urines per pool), collected in the 2nd and 3rd trimesters of pregnancy, respectively. Thyroid stimulating hormone (TSH) and total thyroxine (T4) levels were determined in newborns from a heel-prick blood spot. Maternal iodine and selenium were assessed in urine and serum, respectively. Adjusted linear regression (uni-pollutant model) and Bayesian Kernel Machine Regression (BKMR, mixture model) were applied to study overall and sex-stratified associations between chemicals and hormone concentrations. Interaction with child sex was detected for several compounds. Triclosan, three parabens, and one phthalate metabolite (OH-MPHP) were negatively associated with T4 among girls in the uni-pollutant model. BKMR also suggested a negative association between the mixture and T4 in girls, whereas in boys the association was positive. The mixture was not linked to TSH levels, and for this hormone the uni-pollutant model revealed associations with only a few compounds. Our study, based on repeated urine samples to assess exposure, showed that prenatal exposure to some phenols and phthalates disturb thyroid hormone homeostasis at birth. Furthermore, both uni-pollutant and mixture models, suggested effect modification by child sex, while, to date underlying mechanisms for such sex-differences are not well understood. Background: In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with improved exposure assessment (i.e., repeated urine samples) are needed to evaluate effects of these compounds, individually or as a mixture, in humans. We studied the associations between prenatal exposure to non-persistent environmental chemicals and neonatal thyroid hormones. Methods: The study population consisted of 442 mother–child pairs from the French SEPAGES mother–child cohort recruited between July 2014 and July 2017. For each participant, four parabens, five bisphenols, triclosan, triclocarban, benzophenone-3 as well as metabolites of phthalates and of di(isononyl)cyclohexane-1,2-dicarboxylate were assessed in two pools of repeated urine samples (median: 21 spot urines per pool), collected in the 2nd and 3rd trimesters of pregnancy, respectively. Thyroid stimulating hormone (TSH) and total thyroxine (T4) levels were determined in newborns from a heel-prick blood spot. Maternal iodine and selenium were assessed in urine and serum, respectively. Adjusted linear regression (uni-pollutant model) and Bayesian Kernel Machine Regression (BKMR, mixture model) were applied to study overall and sex-stratified associations between chemicals and hormone concentrations. Results: Interaction with child sex was detected for several compounds. Triclosan, three parabens, and one phthalate metabolite (OH-MPHP) were negatively associated with T4 among girls in the uni-pollutant model. BKMR also suggested a negative association between the mixture and T4 in girls, whereas in boys the association was positive. The mixture was not linked to TSH levels, and for this hormone the uni-pollutant model revealed associations with only a few compounds. Conclusion: Our study, based on repeated urine samples to assess exposure, showed that prenatal exposure to some phenols and phthalates disturb thyroid hormone homeostasis at birth. Furthermore, both uni-pollutant and mixture models, suggested effect modification by child sex, while, to date underlying mechanisms for such sex-differences are not well understood.
ArticleNumber	107840
Author	Malatesta, Andres Philippat, Claire Pin, Isabelle Sakhi, Amrit K. Sophie Gauchez, Anne Guergour, Dorra Coiffier, Ophélie Sabaredzovic, Azemira Nakiwala, Dorothy Rolland, Matthieu Faure, Patrice Slama, Rémy Corne, Christelle Lyon-Caen, Sarah Chovelon, Benoît Thomsen, Cathrine
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Cites_doi	10.1016/j.jchromb.2015.08.040 10.1289/EHP500 10.1210/jcem-56-2-260 10.3390/ijerph17217711 10.1016/j.envint.2020.105678 10.1007/s00216-004-2946-x 10.1039/AN9901500813 10.1016/j.envint.2020.105509 10.1016/j.ijheh.2018.03.010 10.1016/j.scitotenv.2020.140678 10.3390/ijerph18094584 10.1016/j.envres.2016.07.002 10.1016/j.envpol.2021.117650 10.1016/j.tox.2012.05.023 10.1016/j.scitotenv.2017.11.048 10.3390/ijns6010017 10.1016/j.envint.2019.105123 10.1016/j.envint.2018.02.037 10.1097/EDE.0000000000000460 10.1371/journal.pone.0159398 10.1186/1476-069X-11-29 10.1097/EDE.0000000000000722 10.1016/j.envint.2021.106795 10.1289/EHP6740 10.1089/thy.2014.0589 10.1186/s12940-019-0459-5 10.1089/thy.2007.0180 10.1097/EDE.0000000000000716 10.1289/EHP10239 10.1186/1476-069X-13-106 10.1016/j.envint.2018.01.006 10.1111/bdi.12150 10.1093/biostatistics/kxu058 10.3390/ijerph16203888 10.1016/j.envres.2018.05.005 10.1016/j.envres.2020.109710 10.1289/ehp.1103634 10.1371/journal.pone.0123884
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Copyright	2023 The Authors Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved. Distributed under a Creative Commons Attribution 4.0 International License
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Keywords	MEHP oxo-MINCH DiNP MMCHP Heel-prick blood spot Mixture MBzP oxo-MiNP Bisphenols ΣDiNP DEHP OH-MPHP Thyroid hormones ΣDINCH T3 WHO LOD T4 MEOHP MEHHP TSH MnBP Oh-MINCH Phthalates DINCH DEP MiBP Parabens LOQ Oh-MiNP BKMR ΣDEHP MECPP MEP cx-MiNP
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PublicationDate	March 2023 2023-03-00 20230301 2023-03 2023-03-01
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PublicationTitle	Environment international
PublicationTitleAlternate	Environ Int
PublicationYear	2023
Publisher	Elsevier Ltd Elsevier
Publisher_xml	– name: Elsevier Ltd – name: Elsevier
References	Bauer, Glenn, Pilhatsch (b0025) 2014; 16 Lyon-Caen, Siroux, Lepeule (b0120) 2019; 16 Herbstman, Apelberg, Witter (b0085) 2008; 18 Rolland, Lyon-Caen, Sakhi (b0165) 2020 Mortamais, Chevrier, Philippat (b0130) 2012; 11 Paul, Hedge, Bansal (b0140) 2012; 300 Berger, Gunier, Chevrier (b0030) 2018; 165 de Cock, de Boer, Lamoree (b0040) 2014; 13 Guo, Wu, Gao (b0065) 2020; 17 Philippat, Calafat (b0150) 2020; 110275 Villanger, Drover, Nethery (b0205) 2020; 137 Helsel (b0080) 2011 World Health Organization. Urinary Iodine Concentrations for Determining Iodine Status in Populations. World Health Organizations; 2013. Kuo, Su, Wu (b0110) 2015; 10 Perrier, Giorgis-Allemand, Slama (b0145) 2016; 27 Li, Guo, Wu (b0115) 2020; 188 Aker, Watkins, Johns (b0005) 2016; 151 Aker, Ferguson, Rosario (b0015) 2019; 18 Allain, Mauras, Dougé (b0020) 1990; 115 Hegedüs, Perrild, Poulsen (b0075) 1983; 56 Aker, Johns, McElrath (b0010) 2018; 113 Philippat, Rolland, Lyon-Caen (b0160) 2021; 287 Huang, Kuo, Chang (b0105) 2018; 619–620 Gao, Wu, Xu (b0060) 2017 Huang H-B, Chuang C-J, Su P-H, et al. Prenatal and Childhood Exposure to Phthalate Diesters and Thyroid Function in a 9-Year Follow-up Birth Cohort Study: Taiwan Maternal and Infant Cohort Study. Epidemiology 2017;28 Suppl 1:S10–S18; doi: 10.1097/EDE.0000000000000722. Romano, Eliot, Zoeller (b0170) 2018; 221 Tassinari, Tait, Busani (b0195) 2021; 18 Philippat, Mortamais, Chevrier (b0155) 2012; 120 Wang, Ouyang, Feng (b0210) 2017; 125 Souter, Bellavia, Williams (b0185) 2020; 128 Sabaredzovic, Sakhi, Brantsaeter (b0175) 2015; 1002 Stürup, Hayes, Peters (b0190) 2005; 381 Ehrenkranz, Bach, Snow (b0055) 2015; 25 US EPA (U.S. Environmental Protection Agency), 2020. Toxcast & Tox21 Summary Files from invitrodb_v3_3. Retrieved from Minatoya, Sasaki, Araki (b0125) 2017; 28 Derakhshan, Shu, Broeren (b0050) 2021; 157 Huang PC, Tsai CH, Liang WY, et al. Early Phthalates Exposure in Pregnant Women Is Associated with Alteration of Thyroid Hormones. PloS one 2016;11(7):e0159398; doi: 10.1371/journal.pone.0159398. Nakiwala, Noyes, Slama (b0135) 2022; 130 Sakhi, Sabaredzovic, Papadopoulou (b0180) 2018; 114 [accessed 21 November 2020]. Hijman, Konrad, Fingerhut (b0090) 2020; 6 Bobb, Valeri, Claus Henn (b0035) 2015; 16 Derakhshan, Shu, Peeters (b0045) 2019; 133 Guo, Wu, Zhang (b0070) 2020; 743 Philippat (10.1016/j.envint.2023.107840_b0160) 2021; 287 Wang (10.1016/j.envint.2023.107840_b0210) 2017; 125 Nakiwala (10.1016/j.envint.2023.107840_b0135) 2022; 130 Lyon-Caen (10.1016/j.envint.2023.107840_b0120) 2019; 16 de Cock (10.1016/j.envint.2023.107840_b0040) 2014; 13 Perrier (10.1016/j.envint.2023.107840_b0145) 2016; 27 Guo (10.1016/j.envint.2023.107840_b0065) 2020; 17 Minatoya (10.1016/j.envint.2023.107840_b0125) 2017; 28 Derakhshan (10.1016/j.envint.2023.107840_b0050) 2021; 157 10.1016/j.envint.2023.107840_b0095 Huang (10.1016/j.envint.2023.107840_b0105) 2018; 619–620 Allain (10.1016/j.envint.2023.107840_b0020) 1990; 115 10.1016/j.envint.2023.107840_b0100 Tassinari (10.1016/j.envint.2023.107840_b0195) 2021; 18 10.1016/j.envint.2023.107840_b0200 Villanger (10.1016/j.envint.2023.107840_b0205) 2020; 137 Herbstman (10.1016/j.envint.2023.107840_b0085) 2008; 18 Bauer (10.1016/j.envint.2023.107840_b0025) 2014; 16 Helsel (10.1016/j.envint.2023.107840_b0080) 2011 Bobb (10.1016/j.envint.2023.107840_b0035) 2015; 16 Ehrenkranz (10.1016/j.envint.2023.107840_b0055) 2015; 25 Kuo (10.1016/j.envint.2023.107840_b0110) 2015; 10 Aker (10.1016/j.envint.2023.107840_b0005) 2016; 151 Guo (10.1016/j.envint.2023.107840_b0070) 2020; 743 Philippat (10.1016/j.envint.2023.107840_b0155) 2012; 120 Gao (10.1016/j.envint.2023.107840_b0060) 2017 Philippat (10.1016/j.envint.2023.107840_b0150) 2020; 110275 Sabaredzovic (10.1016/j.envint.2023.107840_b0175) 2015; 1002 Berger (10.1016/j.envint.2023.107840_b0030) 2018; 165 Hegedüs (10.1016/j.envint.2023.107840_b0075) 1983; 56 Sakhi (10.1016/j.envint.2023.107840_b0180) 2018; 114 Aker (10.1016/j.envint.2023.107840_b0015) 2019; 18 Romano (10.1016/j.envint.2023.107840_b0170) 2018; 221 Derakhshan (10.1016/j.envint.2023.107840_b0045) 2019; 133 Rolland (10.1016/j.envint.2023.107840_b0165) 2020 Souter (10.1016/j.envint.2023.107840_b0185) 2020; 128 Hijman (10.1016/j.envint.2023.107840_b0090) 2020; 6 Mortamais (10.1016/j.envint.2023.107840_b0130) 2012; 11 Stürup (10.1016/j.envint.2023.107840_b0190) 2005; 381 Li (10.1016/j.envint.2023.107840_b0115) 2020; 188 10.1016/j.envint.2023.107840_b0215 Paul (10.1016/j.envint.2023.107840_b0140) 2012; 300 Aker (10.1016/j.envint.2023.107840_b0010) 2018; 113
References_xml	– volume: 110275 year: 2020 ident: b0150 article-title: Comparison of strategies to efficiently combine repeated urine samples in biomarker-based studies publication-title: Environmental Research – volume: 13 start-page: 106 year: 2014 ident: b0040 article-title: Prenatal exposure to endocrine disrupting chemicals in relation to thyroid hormone levels in infants - a Dutch prospective cohort study publication-title: Environ Health – volume: 120 start-page: 464 year: 2012 end-page: 470 ident: b0155 article-title: Exposure to phthalates and phenols during pregnancy and offspring size at birth publication-title: Environmental health perspectives – year: 2020 ident: b0165 article-title: Exposure to Phenols during Pregnancy and the First Year of Life in a New Type of Couple-Child Cohort Relying on Repeated Urine Biospecimens publication-title: Environ Int – reference: World Health Organization. Urinary Iodine Concentrations for Determining Iodine Status in Populations. World Health Organizations; 2013. – volume: 18 start-page: 28 year: 2019 ident: b0015 article-title: A repeated measures study of phenol, paraben and Triclocarban urinary biomarkers and circulating maternal hormones during gestation in the Puerto Rico PROTECT cohort publication-title: Environmental Health – volume: 16 start-page: 58 year: 2014 end-page: 71 ident: b0025 article-title: Gender differences in thyroid system function: relevance to bipolar disorder and its treatment publication-title: Bipolar Disord – volume: 128 start-page: 67007 year: 2020 ident: b0185 article-title: Urinary Concentrations of Phthalate Metabolite Mixtures in Relation to Serum Biomarkers of Thyroid Function and Autoimmunity among Women from a Fertility Center publication-title: Environ Health Perspect – volume: 165 start-page: 379 year: 2018 end-page: 386 ident: b0030 article-title: Associations of maternal exposure to triclosan, parabens, and other phenols with prenatal maternal and neonatal thyroid hormone levels publication-title: Environ Res – volume: 16 year: 2019 ident: b0120 article-title: Deciphering the Impact of Early-Life Exposures to Highly Variable Environmental Factors on Foetal and Child Health: Design of SEPAGES Couple-Child Cohort publication-title: Int J Environ Res Public Health – volume: 133 year: 2019 ident: b0045 article-title: Association of urinary bisphenols and triclosan with thyroid function during early pregnancy publication-title: Environment International – reference: US EPA (U.S. Environmental Protection Agency), 2020. Toxcast & Tox21 Summary Files from invitrodb_v3_3. Retrieved from – volume: 114 start-page: 242 year: 2018 end-page: 251 ident: b0180 article-title: Levels, variability and determinants of environmental phenols in pairs of Norwegian mothers and children publication-title: Environment International – volume: 157 year: 2021 ident: b0050 article-title: Association of phthalate exposure with thyroid function during pregnancy publication-title: Environment International – volume: 25 start-page: 954 year: 2015 end-page: 961 ident: b0055 article-title: Circadian and Circannual Rhythms in Thyroid Hormones: Determining the TSH and Free T4 Reference Intervals Based Upon Time of Day, Age, and Sex publication-title: Thyroid – volume: 56 start-page: 260 year: 1983 end-page: 263 ident: b0075 article-title: The determination of thyroid volume by ultrasound and its relationship to body weight, age, and sex in normal subjects publication-title: J Clin Endocrinol Metab – volume: 300 start-page: 31 year: 2012 end-page: 45 ident: b0140 article-title: Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-action publication-title: Toxicology – volume: 11 start-page: 29 year: 2012 ident: b0130 article-title: Correcting for the influence of sampling conditions on biomarkers of exposure to phenols and phthalates: a 2-step standardization method based on regression residuals publication-title: Environmental health : a global access science source – volume: 125 year: 2017 ident: b0210 article-title: Maternal Urinary Triclosan Concentration in Relation to Maternal and Neonatal Thyroid Hormone Levels: A Prospective Study publication-title: Environ Health Perspect – year: 2011 ident: b0080 article-title: Statistics for Censored Environmental Data Using Minitab and R – volume: 16 start-page: 493 year: 2015 end-page: 508 ident: b0035 article-title: Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures publication-title: Biostatistics – volume: 28 start-page: S3 year: 2017 end-page: S9 ident: b0125 article-title: Cord Blood Bisphenol A Levels and Reproductive and Thyroid Hormone Levels of Neonates: The Hokkaido Study on Environment and Children’s Health publication-title: Epidemiology – volume: 151 start-page: 30 year: 2016 end-page: 37 ident: b0005 article-title: Phenols and parabens in relation to reproductive and thyroid hormones in pregnant women publication-title: Environmental research – volume: 113 start-page: 341 year: 2018 end-page: 349 ident: b0010 article-title: Associations between maternal phenol and paraben urinary biomarkers and maternal hormones during pregnancy: A repeated measures study publication-title: Environ Int – volume: 130 start-page: 117004 year: 2022 ident: b0135 article-title: Phenol and phthalate effects on thyroid hormone levels during pregnancy: Relying on in-vitro assays and Adverse Outcome Pathways to inform an epidemiological analysis publication-title: Environ Health Perspect – reference: Huang H-B, Chuang C-J, Su P-H, et al. Prenatal and Childhood Exposure to Phthalate Diesters and Thyroid Function in a 9-Year Follow-up Birth Cohort Study: Taiwan Maternal and Infant Cohort Study. Epidemiology 2017;28 Suppl 1:S10–S18; doi: 10.1097/EDE.0000000000000722. – volume: 17 start-page: 7711 year: 2020 ident: b0065 article-title: Meconium Exposure to Phthalates, Sex and Thyroid Hormones, Birth Size and Pregnancy Outcomes in 251 Mother-Infant Pairs from Shanghai publication-title: Int J Environ Res Public Health – volume: 287 year: 2021 ident: b0160 article-title: Pre- and early post-natal exposure to phthalates and DINCH in a new type of mother-child cohort relying on within-subject pools of repeated urine samples publication-title: Environmental Pollution – volume: 10 year: 2015 ident: b0110 article-title: Relationship of Urinary Phthalate Metabolites with Serum Thyroid Hormones in Pregnant Women and Their Newborns: A Prospective Birth Cohort in Taiwan publication-title: PLoS One – volume: 619–620 start-page: 1058 year: 2018 end-page: 1065 ident: b0105 article-title: Longitudinal assessment of prenatal phthalate exposure on serum and cord thyroid hormones homeostasis during pregnancy - Tainan birth cohort study (TBCS) publication-title: Science of The Total Environment – reference: Huang PC, Tsai CH, Liang WY, et al. Early Phthalates Exposure in Pregnant Women Is Associated with Alteration of Thyroid Hormones. PloS one 2016;11(7):e0159398; doi: 10.1371/journal.pone.0159398. – volume: 137 year: 2020 ident: b0205 article-title: Associations between urine phthalate metabolites and thyroid function in pregnant women and the influence of iodine status publication-title: Environ Int – volume: 188 year: 2020 ident: b0115 article-title: Effects of prenatal exposure to five parabens on neonatal thyroid function and birth weight: Evidence from SMBCS study publication-title: Environmental Research – volume: 18 start-page: 4584 year: 2021 ident: b0195 article-title: Toxicological Assessment of Oral Co-Exposure to Bisphenol A (BPA) and Bis(2-ethylhexyl) Phthalate (DEHP) in Juvenile Rats at Environmentally Relevant Dose Levels: Evaluation of the Synergic, Additive or Antagonistic Effects publication-title: Int J Environ Res Public Health – volume: 6 start-page: 17 year: 2020 ident: b0090 article-title: Determining Reference Ranges for Total T4 in Dried Blood Samples for Newborn Screening publication-title: Int J Neonatal Screen – volume: 115 start-page: 813 year: 1990 end-page: 815 ident: b0020 article-title: Determination of iodine and bromine in plasma and urine by inductively coupled plasma mass spectrometry publication-title: Analyst – volume: 743 year: 2020 ident: b0070 article-title: Maternal and childhood urinary phenol concentrations, neonatal thyroid function, and behavioral problems at 10 years of age: The SMBCS study publication-title: Science of The Total Environment – volume: 27 start-page: 378 year: 2016 end-page: 388 ident: b0145 article-title: Within-subject Pooling of Biological Samples to Reduce Exposure Misclassification in Biomarker-based Studies publication-title: Epidemiology (Cambridge, Mass) – volume: 1002 start-page: 343 year: 2015 end-page: 352 ident: b0175 article-title: Determination of 12 urinary phthalate metabolites in Norwegian pregnant women by core-shell high performance liquid chromatography with on-line solid-phase extraction, column switching and tandem mass spectrometry publication-title: Journal of chromatography B, Analytical technologies in the biomedical and life sciences – volume: 221 start-page: 623 year: 2018 end-page: 631 ident: b0170 article-title: Maternal urinary phthalate metabolites during pregnancy and thyroid hormone concentrations in maternal and cord sera: The HOME Study publication-title: Int J Hyg Environ Health – start-page: 7 year: 2017 ident: b0060 article-title: Effects of Prenatal Phthalate Exposure on Thyroid Hormone Concentrations Beginning at The Embryonic Stage publication-title: Sci Rep – reference: [accessed 21 November 2020]. – volume: 18 start-page: 67 year: 2008 end-page: 76 ident: b0085 article-title: Maternal, infant, and delivery factors associated with neonatal thyroid hormone status publication-title: Thyroid – volume: 381 start-page: 686 year: 2005 end-page: 694 ident: b0190 article-title: Development and application of a simple routine method for the determination of selenium in serum by octopole reaction system ICPMS publication-title: Anal Bioanal Chem – volume: 1002 start-page: 343 year: 2015 ident: 10.1016/j.envint.2023.107840_b0175 article-title: Determination of 12 urinary phthalate metabolites in Norwegian pregnant women by core-shell high performance liquid chromatography with on-line solid-phase extraction, column switching and tandem mass spectrometry publication-title: Journal of chromatography B, Analytical technologies in the biomedical and life sciences doi: 10.1016/j.jchromb.2015.08.040 – volume: 125 issue: 6 year: 2017 ident: 10.1016/j.envint.2023.107840_b0210 article-title: Maternal Urinary Triclosan Concentration in Relation to Maternal and Neonatal Thyroid Hormone Levels: A Prospective Study publication-title: Environ Health Perspect doi: 10.1289/EHP500 – year: 2011 ident: 10.1016/j.envint.2023.107840_b0080 – volume: 56 start-page: 260 issue: 2 year: 1983 ident: 10.1016/j.envint.2023.107840_b0075 article-title: The determination of thyroid volume by ultrasound and its relationship to body weight, age, and sex in normal subjects publication-title: J Clin Endocrinol Metab doi: 10.1210/jcem-56-2-260 – volume: 17 start-page: 7711 issue: 21 year: 2020 ident: 10.1016/j.envint.2023.107840_b0065 article-title: Meconium Exposure to Phthalates, Sex and Thyroid Hormones, Birth Size and Pregnancy Outcomes in 251 Mother-Infant Pairs from Shanghai publication-title: Int J Environ Res Public Health doi: 10.3390/ijerph17217711 – start-page: 7 year: 2017 ident: 10.1016/j.envint.2023.107840_b0060 article-title: Effects of Prenatal Phthalate Exposure on Thyroid Hormone Concentrations Beginning at The Embryonic Stage publication-title: Sci Rep – year: 2020 ident: 10.1016/j.envint.2023.107840_b0165 article-title: Exposure to Phenols during Pregnancy and the First Year of Life in a New Type of Couple-Child Cohort Relying on Repeated Urine Biospecimens publication-title: Environ Int doi: 10.1016/j.envint.2020.105678 – volume: 381 start-page: 686 issue: 3 year: 2005 ident: 10.1016/j.envint.2023.107840_b0190 article-title: Development and application of a simple routine method for the determination of selenium in serum by octopole reaction system ICPMS publication-title: Anal Bioanal Chem doi: 10.1007/s00216-004-2946-x – volume: 115 start-page: 813 issue: 6 year: 1990 ident: 10.1016/j.envint.2023.107840_b0020 article-title: Determination of iodine and bromine in plasma and urine by inductively coupled plasma mass spectrometry publication-title: Analyst doi: 10.1039/AN9901500813 – volume: 137 year: 2020 ident: 10.1016/j.envint.2023.107840_b0205 article-title: Associations between urine phthalate metabolites and thyroid function in pregnant women and the influence of iodine status publication-title: Environ Int doi: 10.1016/j.envint.2020.105509 – volume: 221 start-page: 623 issue: 4 year: 2018 ident: 10.1016/j.envint.2023.107840_b0170 article-title: Maternal urinary phthalate metabolites during pregnancy and thyroid hormone concentrations in maternal and cord sera: The HOME Study publication-title: Int J Hyg Environ Health doi: 10.1016/j.ijheh.2018.03.010 – volume: 743 year: 2020 ident: 10.1016/j.envint.2023.107840_b0070 article-title: Maternal and childhood urinary phenol concentrations, neonatal thyroid function, and behavioral problems at 10 years of age: The SMBCS study publication-title: Science of The Total Environment doi: 10.1016/j.scitotenv.2020.140678 – volume: 110275 year: 2020 ident: 10.1016/j.envint.2023.107840_b0150 article-title: Comparison of strategies to efficiently combine repeated urine samples in biomarker-based studies publication-title: Environmental Research – volume: 18 start-page: 4584 issue: 9 year: 2021 ident: 10.1016/j.envint.2023.107840_b0195 article-title: Toxicological Assessment of Oral Co-Exposure to Bisphenol A (BPA) and Bis(2-ethylhexyl) Phthalate (DEHP) in Juvenile Rats at Environmentally Relevant Dose Levels: Evaluation of the Synergic, Additive or Antagonistic Effects publication-title: Int J Environ Res Public Health doi: 10.3390/ijerph18094584 – volume: 151 start-page: 30 year: 2016 ident: 10.1016/j.envint.2023.107840_b0005 article-title: Phenols and parabens in relation to reproductive and thyroid hormones in pregnant women publication-title: Environmental research doi: 10.1016/j.envres.2016.07.002 – volume: 287 year: 2021 ident: 10.1016/j.envint.2023.107840_b0160 article-title: Pre- and early post-natal exposure to phthalates and DINCH in a new type of mother-child cohort relying on within-subject pools of repeated urine samples publication-title: Environmental Pollution doi: 10.1016/j.envpol.2021.117650 – volume: 300 start-page: 31 issue: 1–2 year: 2012 ident: 10.1016/j.envint.2023.107840_b0140 article-title: Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-action publication-title: Toxicology doi: 10.1016/j.tox.2012.05.023 – volume: 619–620 start-page: 1058 year: 2018 ident: 10.1016/j.envint.2023.107840_b0105 article-title: Longitudinal assessment of prenatal phthalate exposure on serum and cord thyroid hormones homeostasis during pregnancy - Tainan birth cohort study (TBCS) publication-title: Science of The Total Environment doi: 10.1016/j.scitotenv.2017.11.048 – volume: 6 start-page: 17 issue: 1 year: 2020 ident: 10.1016/j.envint.2023.107840_b0090 article-title: Determining Reference Ranges for Total T4 in Dried Blood Samples for Newborn Screening publication-title: Int J Neonatal Screen doi: 10.3390/ijns6010017 – volume: 133 year: 2019 ident: 10.1016/j.envint.2023.107840_b0045 article-title: Association of urinary bisphenols and triclosan with thyroid function during early pregnancy publication-title: Environment International doi: 10.1016/j.envint.2019.105123 – volume: 114 start-page: 242 year: 2018 ident: 10.1016/j.envint.2023.107840_b0180 article-title: Levels, variability and determinants of environmental phenols in pairs of Norwegian mothers and children publication-title: Environment International doi: 10.1016/j.envint.2018.02.037 – volume: 27 start-page: 378 issue: 3 year: 2016 ident: 10.1016/j.envint.2023.107840_b0145 article-title: Within-subject Pooling of Biological Samples to Reduce Exposure Misclassification in Biomarker-based Studies publication-title: Epidemiology (Cambridge, Mass) doi: 10.1097/EDE.0000000000000460 – ident: 10.1016/j.envint.2023.107840_b0095 doi: 10.1371/journal.pone.0159398 – ident: 10.1016/j.envint.2023.107840_b0215 – volume: 11 start-page: 29 issue: 1 year: 2012 ident: 10.1016/j.envint.2023.107840_b0130 article-title: Correcting for the influence of sampling conditions on biomarkers of exposure to phenols and phthalates: a 2-step standardization method based on regression residuals publication-title: Environmental health : a global access science source doi: 10.1186/1476-069X-11-29 – ident: 10.1016/j.envint.2023.107840_b0100 doi: 10.1097/EDE.0000000000000722 – volume: 157 year: 2021 ident: 10.1016/j.envint.2023.107840_b0050 article-title: Association of phthalate exposure with thyroid function during pregnancy publication-title: Environment International doi: 10.1016/j.envint.2021.106795 – volume: 128 start-page: 67007 issue: 6 year: 2020 ident: 10.1016/j.envint.2023.107840_b0185 article-title: Urinary Concentrations of Phthalate Metabolite Mixtures in Relation to Serum Biomarkers of Thyroid Function and Autoimmunity among Women from a Fertility Center publication-title: Environ Health Perspect doi: 10.1289/EHP6740 – volume: 25 start-page: 954 issue: 8 year: 2015 ident: 10.1016/j.envint.2023.107840_b0055 article-title: Circadian and Circannual Rhythms in Thyroid Hormones: Determining the TSH and Free T4 Reference Intervals Based Upon Time of Day, Age, and Sex publication-title: Thyroid doi: 10.1089/thy.2014.0589 – volume: 18 start-page: 28 issue: 1 year: 2019 ident: 10.1016/j.envint.2023.107840_b0015 article-title: A repeated measures study of phenol, paraben and Triclocarban urinary biomarkers and circulating maternal hormones during gestation in the Puerto Rico PROTECT cohort publication-title: Environmental Health doi: 10.1186/s12940-019-0459-5 – volume: 18 start-page: 67 issue: 1 year: 2008 ident: 10.1016/j.envint.2023.107840_b0085 article-title: Maternal, infant, and delivery factors associated with neonatal thyroid hormone status publication-title: Thyroid doi: 10.1089/thy.2007.0180 – volume: 28 start-page: S3 issue: Suppl 1 year: 2017 ident: 10.1016/j.envint.2023.107840_b0125 article-title: Cord Blood Bisphenol A Levels and Reproductive and Thyroid Hormone Levels of Neonates: The Hokkaido Study on Environment and Children’s Health publication-title: Epidemiology doi: 10.1097/EDE.0000000000000716 – volume: 130 start-page: 117004 year: 2022 ident: 10.1016/j.envint.2023.107840_b0135 article-title: Phenol and phthalate effects on thyroid hormone levels during pregnancy: Relying on in-vitro assays and Adverse Outcome Pathways to inform an epidemiological analysis publication-title: Environ Health Perspect doi: 10.1289/EHP10239 – volume: 13 start-page: 106 year: 2014 ident: 10.1016/j.envint.2023.107840_b0040 article-title: Prenatal exposure to endocrine disrupting chemicals in relation to thyroid hormone levels in infants - a Dutch prospective cohort study publication-title: Environ Health doi: 10.1186/1476-069X-13-106 – volume: 113 start-page: 341 year: 2018 ident: 10.1016/j.envint.2023.107840_b0010 article-title: Associations between maternal phenol and paraben urinary biomarkers and maternal hormones during pregnancy: A repeated measures study publication-title: Environ Int doi: 10.1016/j.envint.2018.01.006 – volume: 16 start-page: 58 issue: 1 year: 2014 ident: 10.1016/j.envint.2023.107840_b0025 article-title: Gender differences in thyroid system function: relevance to bipolar disorder and its treatment publication-title: Bipolar Disord doi: 10.1111/bdi.12150 – volume: 16 start-page: 493 issue: 3 year: 2015 ident: 10.1016/j.envint.2023.107840_b0035 article-title: Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures publication-title: Biostatistics doi: 10.1093/biostatistics/kxu058 – volume: 16 issue: 20 year: 2019 ident: 10.1016/j.envint.2023.107840_b0120 article-title: Deciphering the Impact of Early-Life Exposures to Highly Variable Environmental Factors on Foetal and Child Health: Design of SEPAGES Couple-Child Cohort publication-title: Int J Environ Res Public Health doi: 10.3390/ijerph16203888 – volume: 165 start-page: 379 year: 2018 ident: 10.1016/j.envint.2023.107840_b0030 article-title: Associations of maternal exposure to triclosan, parabens, and other phenols with prenatal maternal and neonatal thyroid hormone levels publication-title: Environ Res doi: 10.1016/j.envres.2018.05.005 – volume: 188 year: 2020 ident: 10.1016/j.envint.2023.107840_b0115 article-title: Effects of prenatal exposure to five parabens on neonatal thyroid function and birth weight: Evidence from SMBCS study publication-title: Environmental Research doi: 10.1016/j.envres.2020.109710 – volume: 120 start-page: 464 issue: 3 year: 2012 ident: 10.1016/j.envint.2023.107840_b0155 article-title: Exposure to phthalates and phenols during pregnancy and offspring size at birth publication-title: Environmental health perspectives doi: 10.1289/ehp.1103634 – ident: 10.1016/j.envint.2023.107840_b0200 – volume: 10 issue: 6 year: 2015 ident: 10.1016/j.envint.2023.107840_b0110 article-title: Relationship of Urinary Phthalate Metabolites with Serum Thyroid Hormones in Pregnant Women and Their Newborns: A Prospective Birth Cohort in Taiwan publication-title: PLoS One doi: 10.1371/journal.pone.0123884
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Snippet	In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological studies with... Background: In vitro and toxicological studies have shown that non-persistent environmental chemicals can perturb thyroid hormone homeostasis. Epidemiological...
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SubjectTerms	Bayes Theorem Bayesian theory benzophenones Bisphenols blood serum children DINCH environment Environmental Exposure - adverse effects Environmental Pollutants - urine Environmental Sciences exposure assessment Female Heel-prick blood spot homeostasis Hormones Humans Infant, Newborn iodine Male maternal exposure metabolites Mixture Parabens Parabens - analysis Phthalates Phthalic Acids - toxicity Phthalic Acids - urine Pregnancy Prenatal Exposure Delayed Effects regression analysis selenium thyroid function Thyroid Gland Thyroid Hormones Thyrotropin thyroxine triclosan Triclosan - toxicity urine
Title	Exposure to a mixture of non-persistent environmental chemicals and neonatal thyroid function in a cohort with improved exposure assessment
URI	https://dx.doi.org/10.1016/j.envint.2023.107840 https://www.ncbi.nlm.nih.gov/pubmed/36857904 https://www.proquest.com/docview/2781620762 https://www.proquest.com/docview/2834208211 https://hal.science/hal-04015859 https://doaj.org/article/bb93787e3c944b2db4c04f9d22c394f0
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