NK cell phenotypic profile during active TB in people living with HIV-evolution during TB treatment and implications for bacterial clearance and disease severity

Natural killer (NK) cells, key effector cells of the innate immune system, play an important role in the clearance and control of Mycobacterium tuberculosis and HIV infections. Here, we utilized peripheral blood specimens from the Improving Retreatment Success CAPRISA 011 study to characterize NK ce...

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Veröffentlicht in:	Scientific reports Jg. 13; H. 1; S. 11726 - 10
Hauptverfasser:	Maseko, Thando Glory, Rambaran, Santhuri, Ngubane, Slindile, Lewis, Lara, Ngcapu, Sinaye, Hassan-Moosa, Razia, Archary, Derseree, Perumal, Rubeshan, Padayatchi, Nesri, Naidoo, Kogieleum, Sivro, Aida
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 20.07.2023 Nature Publishing Group Nature Portfolio
Schlagworte:	631/250 631/250/2504 631/250/255/1856 631/250/255/1901 Cavitation CD56 Antigen Cell culture Coinfection - pathology Down-regulation Effector cells HIV HIV Infections - complications HIV Infections - drug therapy Human immunodeficiency virus Humanities and Social Sciences Humans Immune clearance Immune system Infections Innate immunity Killer Cells, Natural multidisciplinary Natural killer cells Patient Acuity Peripheral blood Phenotype Phenotypes Science Science (multidisciplinary) Tuberculosis
ISSN:	2045-2322, 2045-2322
Online-Zugang:	Volltext
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