Unraveling the epigenetic code: human kidney DNA methylation and chromatin dynamics in renal disease development

Epigenetic changes may fill a critical gap in our understanding of kidney disease development, as they not only reflect metabolic changes but are also preserved and transmitted during cell division. We conducted a genome-wide cytosine methylation analysis of 399 human kidney samples, along with sing...

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Vydáno v:	Nature communications Ročník 15; číslo 1; s. 873 - 17
Hlavní autoři:	Yan, Yu, Liu, Hongbo, Abedini, Amin, Sheng, Xin, Palmer, Matthew, Li, Hongzhe, Susztak, Katalin
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 29.01.2024 Nature Publishing Group Nature Portfolio
Témata:	38 49/39 692/308 692/4022/1585 Annotations Cell division Chromatin Cytosine Diabetes mellitus DNA methylation Drug development Epigenetics Gene expression Genetic diversity Genome-wide association studies Genomes Humanities and Social Sciences Hypertension Kidney diseases Kidneys multidisciplinary Pathogenesis Proximal tubules Science Science (multidisciplinary)
ISSN:	2041-1723, 2041-1723
On-line přístup:	Získat plný text
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