PFAS exposure during pregnancy: Implications for placental health and functioning

[Display omitted] •First study about the effects of PFAS on human placental histological parameters.•PFTrDA, PFHxPA, PFHpA, and 6:2 diPAP associated with fetal − maternal exchanges.•Women in the moderate/high exposure cluster had reduced placental weight. Animal studies have linked prenatal poly- an...

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Bibliographic Details
Published in:	Environment international Vol. 197; p. 109308
Main Authors:	Khan, Sadia, Ouidir, Marion, Lemaitre, Nicolas, Jovanovic, Nicolas, Bayat, Sam, Lyon-Caen, Sarah, Hoffmann, Pascale, Desseux, Morgane, Thomsen, Cathrine, Couturier-Tarrade, A., Småstuen Haug, Line, Valmary-Degano, Séverine, Siroux, Valérie, Slama, Rémy, Alfaidy, Nadia, Philippat, Claire
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.03.2025 Elsevier
Subjects:	Adult Angiogenesis animals Bayesian theory blood serum calcification cluster analysis Endocrine disruptors environment Environmental Pollutants - blood Environmental Pollutants - toxicity Female Fetal maternal exchanges fibrin Fluorocarbons - blood Fluorocarbons - toxicity Histology Humans Life Sciences Maternal Exposure - statistics & numerical data Mixture Per- and Polyfluoroalkyl Substances perfluorotridecanoic acid Placenta - drug effects Placenta - physiology Placental Vascularization Pregnancy Young Adult Endocrine disruptors DOHaD FPR PFNA PFAS Mixture 6:2 diPAP Angiogenesis Per- and Polyfluoroalkyl Substances PFDA PFHxPA PFTrDA Fetal maternal exchanges PFR PFPeA HPLC LOD PFDoDA PFBS OR PFHxS CI 6:2Cl-PFESA MS Histology PFUnDA PFHpA Placental Vascularization PFOA LOQ GW BKMR br-PFHxS PFHpS PFOS
ISSN:	0160-4120, 1873-6750, 1873-6750
Online Access:	Get full text
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