The diversified role of mitochondria in ferroptosis in cancer

Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation, and it has been studied extensively since its discovery in 2012. Induced by iron overload and ROS accumulation, ferroptosis is modulated by various cellular metabolic and signaling pathways. The GSH-GPX4 path...

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Bibliographic Details
Published in:	Cell death & disease Vol. 14; no. 8; pp. 519 - 12
Main Authors:	Liu, Yu’e, Lu, Shiping, Wu, Lei-lei, Yang, Liang, Yang, Lixue, Wang, Jinghan
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 14.08.2023 Springer Nature B.V Nature Publishing Group
Subjects:	13/2 631/80/82 692/420/755 Antibodies Apoptosis Biochemistry Biomedical and Life Sciences Cancer Cell Biology Cell Culture Cell death Cristae Drug resistance Energy metabolism Ferroptosis Glycolysis Immunology Iron Life Sciences Lipid peroxidation Membrane fusion Membrane potential Metabolism Metastases Mitochondria Oxidative phosphorylation Oxidative stress Phosphorylation Review Review Article Sex hormones Tumor cells
ISSN:	2041-4889, 2041-4889
Online Access:	Get full text
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