Characterization of kallikrein-related peptidase 4 (KLK4) mRNA expression in tumor tissue of advanced high-grade serous ovarian cancer patients

Overexpression of several members of the kallikrein-related peptidase (KLK) family, including KLK4, has been reported in ovarian cancer tissue, consistent with the fact that elevated levels of KLK protein are often also found in serum and in effusion fluids of ovarian cancer patients. In the present...

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Bibliographic Details
Published in:	PloS one Vol. 14; no. 2; p. e0212968
Main Authors:	Gong, Weiwei, Liu, Yueyang, Seidl, Christof, Dreyer, Tobias, Drecoll, Enken, Kotzsch, Matthias, Bronger, Holger, Dorn, Julia, Magdolen, Viktor
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 27.02.2019 Public Library of Science (PLoS)
Subjects:	Adult Aged Aged, 80 and over Analysis Ascites Biology and Life Sciences Cancer patients Cancer research Care and treatment Cystadenocarcinoma, Serous - genetics Cystadenocarcinoma, Serous - pathology Female Gene Expression Regulation, Neoplastic Genomes Genomics Health aspects Humans Kallikrein Kallikreins - genetics Medical research Medicine and Health Sciences Messenger RNA Middle Aged Multivariate Analysis Neoplasm Grading Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Physical Sciences Prognosis Regression analysis Research and Analysis Methods RNA Survival Analysis Tumors Up-Regulation Germany
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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