Urinary extracellular vesicle N-glycomics identifies diagnostic glycosignatures for bladder cancer

Bladder cancer (BC) is the most common urologic malignancy, facing enormous diagnostic challenges. Urinary extracellular vesicles (EVs) are promising source for developing diagnostic markers for bladder cancer because of the direct contact between urine and bladder. This study pioneers urinary EV N-...

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Vydáno v:	Nature communications Ročník 16; číslo 1; s. 2292 - 17
Hlavní autoři:	Li, Yang, Fu, Bin, Wang, Maoyu, Chen, Weiyu, Fan, Jiawei, Li, Yueyue, Liu, Xuejiao, Wang, Jun, Zhang, Zhensheng, Lu, Haojie, Zhang, Ying
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 07.03.2025 Nature Publishing Group Nature Portfolio
Témata:	631/1647/296 631/337/458/1524 631/45/221 82/58 Aged Biomarkers Biomarkers, Tumor - urine Biopsy Bladder Bladder cancer Cancer Comparative analysis Diagnosis Extracellular vesicles Extracellular Vesicles - chemistry Extracellular Vesicles - metabolism Female Glycan Glycomics - methods Glycoproteins Glycoproteins - metabolism Glycoproteins - urine Glycosylation Humanities and Social Sciences Humans Invasiveness Male Malignancy Medical diagnosis Methyl isobutyl carbinol Middle Aged multidisciplinary Muscles N-glycans Polysaccharides Polysaccharides - metabolism Polysaccharides - urine Science Science (multidisciplinary) Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - urine
ISSN:	2041-1723, 2041-1723
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