Accurate prediction of drug-target interactions in Chinese and western medicine by the CWI-DTI model

Accurate prediction of drug-target interactions (DTIs) is crucial for advancing drug discovery and repurposing. Computational methods have significantly improved the efficiency of experimental predictions for drug-target interactions in Western medicine. However, accurately predicting the complex re...

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Bibliographic Details
Published in:	Scientific reports Vol. 14; no. 1; pp. 25054 - 13
Main Authors:	Li, Ying, Zhang, Xingyu, Chen, Zhuo, Yang, Hongye, Liu, Yuhui, Wang, Huiqing, Yan, Ting, Xiang, Jie, Wang, Bin
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 23.10.2024 Nature Publishing Group Nature Portfolio
Subjects:	631/114 631/154 Accuracy Algorithms Autoencoder framework Chinese medicine Computational Biology - methods Datasets Drug databases Drug development Drug discovery Drug Discovery - methods Drug Interactions Drug Repositioning - methods Drug-target interactions Drugs, Chinese Herbal - chemistry Drugs, Chinese Herbal - pharmacology Herbal medicine Heterogeneity Humanities and Social Sciences Humans Medicine Medicine, Chinese Traditional - methods multidisciplinary Noise reduction Predictions Science Science (multidisciplinary) Western medicine Chinese medicine Autoencoder framework Western medicine Drug databases Drug-target interactions
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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