Methicillin-resistant Staphylococcus aureus (MRSA) in men having sex with men (MSM): a systematic review

Background Outbreaks of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have been documented at multiple sites worldwide. Several studies have reported an elevated infection rate of CA-MRSA infections in men having sex with men (MSM), suggesting CA-MRSA can behave as a sexua...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:BMC infectious diseases Ročník 25; číslo 1; s. 299 - 7
Hlavní autoři: de Jong, G. M., van der Boor, S.C., van Bokhoven, C., Bos, H., Hoornenborg, E., Joosten, R.E., Notermans, D.W., de Stoppelaar, S.F.
Médium: Journal Article
Jazyk:angličtina
Vydáno: London BioMed Central 02.03.2025
Springer Nature B.V
BMC
Témata:
Colonization
Community-Acquired Infections - epidemiology
Community-Acquired Infections - microbiology
Community-Acquired Infections - transmission
Condoms
Disease transmission
Drug resistance
Drug use
Hepatitis
Heterosexuality
HIV
Homosexuality, Male - statistics & numerical data
Human immunodeficiency virus
Humans
Infectious Diseases
Internal Medicine
Japan - epidemiology
Literature reviews
Male
Medical Microbiology
Medicine
Medicine & Public Health
Men having sex with men (MSM)
Methicillin
Methicillin-resistant Staphylococcus aureus (MRSA)
Methicillin-Resistant Staphylococcus aureus - isolation & purification
Neutrophils
Parasitology
Pathogens
Prevalence
Public health
Risk Factors
Risk taking
Sex
Sexual behavior
Sexual transmission
Sexually transmitted diseases
Sexually transmitted infections
Staphylococcal Infections - epidemiology
Staphylococcal Infections - microbiology
Staphylococcal Infections - transmission
Staphylococcus aureus
Staphylococcus infections
STD
Systematic review
Tropical Medicine
United States - epidemiology
United States
Japan
Sexual transmission
Methicillin-resistant
Men having sex with men (MSM)
MRSA
Methicillin-resistant Staphylococcus aureus (MRSA)
ISSN:1471-2334, 1471-2334
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Background Outbreaks of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have been documented at multiple sites worldwide. Several studies have reported an elevated infection rate of CA-MRSA infections in men having sex with men (MSM), suggesting CA-MRSA can behave as a sexually transmitted infection (STI). To assess the potential public health impact of CA-MRSA transmission amongst MSM, a systematic review of the literature was conducted to identify risk factors and prevalence of CA-MRSA colonization and infection in MSM. Methods The electronic database Embase.com (containing Embase and Medline) was systematically searched to identify studies investigating CA-MRSA colonization and infection from inception up to 19 January 2024. Two independent reviewers selected potentially relevant articles for full-text screening. Only English-language articles meeting the inclusion criteria were considered. In case of reviewer disagreement, a third independent reviewer was consulted. Information regarding prevalence, strains, and risk factors for CA-MRSA colonization and infection were extracted by one reviewer and checked by a second reviewer. Results 54 studies were screened; 18 were included for analysis. Notably, 3 distinct CA-MRSA clusters were observed in MSM in the USA and Japan. Screening in other MSM cohorts did not reveal an elevated prevalence of CA-MRSA colonization or infection. Identifying as MSM by itself is not a risk factor for MRSA colonization and infection, but specific behavior factors such as intravenous drugs use and high-risk sexual behavior do increase this risk. Discussion Recognizing the potential presence of CA-MRSA in MSM experiencing (skin) infections is crucial for informed clinical decisions. In cases where a cluster of CA-MRSA infections occurs within a sexual network, eradication strategies and non-pharmaceutical interventions should be carefully considered to prevent further spreading. Given the limited available data on this topic and incomplete data on the prevalence on a global scale, further investigations should prioritize studying the impact of CA-MRSA transmission within sexual networks.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Article-2
ObjectType-Undefined-1
ObjectType-Feature-3
content type line 23
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-025-10593-3