Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development

RTS,S and R21 are the only vaccines recommended by the WHO to protect children from Plasmodium falciparum (Pf) clinical malaria. Both vaccines target the Pf sporozoite surface protein circumsporozoite protein (CSP). Recent studies showed that human antibodies neutralize Pf sporozoites most efficient...

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Bibliographic Details

Published in:	npj vaccines Vol. 9; no. 1; pp. 225 - 17
Main Authors:	Krenger, Pascal S., Roques, Magali, Vogt, Anne-Cathrine S., Pardini, Alessandro, Rothen, Dominik A., Balke, Ina, Schnider, Sophie T., Mohsen, Mona O., Heussler, Volker T., Zeltins, Andris, Bachmann, Martin F.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 18.11.2024 Nature Publishing Group Nature Portfolio
Subjects:	631/250/255/1629 631/250/590/2294 Antibodies Biomedical and Life Sciences Biomedicine Immunogenicity Infectious Diseases Malaria Medical Microbiology Proteins Public Health Vaccine Vaccines Vector-borne diseases Virology
ISSN:	2059-0105, 2059-0105
Online Access:	Get full text
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