Pharmacokinetic Study of Levetiracetam in Children

Purpose: The pharmacokinetics of the novel antiepileptic drug (AED) levetiracetam and its major metabolite, ucb L057, were studied in children with partial seizures in a multicenter, open‐label, single‐dose study. Methods: Twenty‐four children (15 boys, nine girls), 6 to 12 years old, received a sin...

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Bibliographic Details
Published in:	Epilepsia (Copenhagen) Vol. 42; no. 12; pp. 1574 - 1579
Main Authors:	Pellock, John M., Glauser, Tracy A., Bebin, E. Martina, Fountain, Nathan B., Ritter, Frank J., Coupez, René M., Shields, W. Donald
Format:	Journal Article
Language:	English
Published:	Boston, MA, USA Blackwell Science Inc 01.12.2001 Blackwell
Subjects:	Adult Age Factors Anticonvulsants - pharmacokinetics Anticonvulsants - therapeutic use Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Child Creatine - metabolism Epilepsy Epilepsy - drug therapy Epilepsy - metabolism Female Humans Keppra Levetiracetam Male Medical sciences Metabolic Clearance Rate Middle Aged Neuropharmacology Pediatric Pharmacokinetics Pharmacology. Drug treatments Piracetam - analogs & derivatives Piracetam - pharmacokinetics Piracetam - therapeutic use ucb L057 Human Nervous system diseases Metabolite Epilepsy Multicenter study Anticonvulsant Clearance Metabolism Cerebral disorder Chemotherapy Treatment Partial Central nervous system disease Pharmacokinetics Child Levetiracetam
ISSN:	0013-9580, 1528-1167
Online Access:	Get full text
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