Gaps in policy-relevant information on burden of disease in children: a systematic review

Valid information about cause-specific child mortality and morbidity is an essential foundation for national and international health policy. We undertook a systematic review to investigate the geographical dispersion of and time trends in publication for policy-relevant information about children&#...

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Veröffentlicht in:The Lancet (British edition) Jg. 365; H. 9476; S. 2031 - 2040
Hauptverfasser: Rudan, Igor, Lawn, Joy, Cousens, Simon, Rowe, Alexander K, Boschi-Pinto, Cynthia, Tomašković, Lana, Mendoza, Walter, Lanata, Claudio F, Roca-Feltrer, Arantxa, Carneiro, Ilona, Schellenberg, Joanna A, Polašek, Ozren, Weber, Martin, Bryce, Jennifer, Morris, Saul S, Black, Robert E, Campbell, Harry
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Elsevier Ltd 11.06.2005
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ISSN:0140-6736, 1474-547X, 1474-547X
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Abstract Valid information about cause-specific child mortality and morbidity is an essential foundation for national and international health policy. We undertook a systematic review to investigate the geographical dispersion of and time trends in publication for policy-relevant information about children's health and to assess associations between the availability of reliable data and poverty. We identified data available on Jan 1, 2001, and published since 1980, for the major causes of morbidity and mortality in young children. Studies with relevant data were assessed against a set of inclusion criteria to identify those likely to provide unbiased estimates of the burden of childhood disease in the community. Only 308 information units from more than 17 000 papers identified were regarded as possible unbiased sources for estimates of childhood disease burden. The geographical distribution of these information units revealed a pattern of small well-researched populations surrounded by large areas with little available information. No reliable population-based data were identified from many of the world's poorest countries, which account for about a third of all deaths of children worldwide. The number of new studies diminished over the last 10 years investigated. The number of population-based studies yielding estimates of burden of childhood disease from less developed countries was low. The decreasing trend over time suggests reductions in research investment in this sphere. Data are especially sparse from the world's least developed countries with the highest child mortality. Guidelines are needed for the conduct of burden-of-disease studies together with an international research policy that gives increased emphasis to global equity and coverage so that knowledge can be generated from all regions of the world.
AbstractList Valid information about cause-specific child mortality and morbidity is an essential foundation for national and international health policy. We undertook a systematic review to investigate the geographical dispersion of and time trends in publication for policy-relevant information about children's health and to assess associations between the availability of reliable data and poverty. We identified data available on Jan 1, 2001, and published since 1980, for the major causes of morbidity and mortality in young children. Studies with relevant data were assessed against a set of inclusion criteria to identify those likely to provide unbiased estimates of the burden of childhood disease in the community. Only 308 information units from more than 17 000 papers identified were regarded as possible unbiased sources for estimates of childhood disease burden. The geographical distribution of these information units revealed a pattern of small well-researched populations surrounded by large areas with little available information. No reliable population-based data were identified from many of the world's poorest countries, which account for about a third of all deaths of children worldwide. The number of new studies diminished over the last 10 years investigated. The number of population-based studies yielding estimates of burden of childhood disease from less developed countries was low. The decreasing trend over time suggests reductions in research investment in this sphere. Data are especially sparse from the world's least developed countries with the highest child mortality. Guidelines are needed for the conduct of burden-of-disease studies together with an international research policy that gives increased emphasis to global equity and coverage so that knowledge can be generated from all regions of the world.
Valid information about cause-specific child mortality and morbidity is an essential foundation for national and international health policy. We undertook a systematic review to investigate the geographical dispersion of and time trends in publication for policy-relevant information about children's health and to assess associations between the availability of reliable data and poverty. We identified data available on Jan 1, 2001, and published since 1980, for the major causes of morbidity and mortality in young children. Studies with relevant data were assessed against a set of inclusion criteria to identify those likely to provide unbiased estimates of the burden of childhood disease in the community. Only 308 information units from more than 17,000 papers identified were regarded as possible unbiased sources for estimates of childhood disease burden. The geographical distribution of these information units revealed a pattern of small well-researched populations surrounded by large areas with little available information. No reliable population-based data were identified from many of the world's poorest countries, which account for about a third of all deaths of children worldwide. The number of new studies diminished over the last 10 years investigated. The number of population-based studies yielding estimates of burden of childhood disease from less developed countries was low. The decreasing trend over time suggests reductions in research investment in this sphere. Data are especially sparse from the world's least developed countries with the highest child mortality. Guidelines are needed for the conduct of burden-of-disease studies together with an international research policy that gives increased emphasis to global equity and coverage so that knowledge can be generated from all regions of the world.
Valid information about cause-specific child mortality and morbidity is an essential foundation for national and international health policy. We undertook a systematic review to investigate the geographical dispersion of and time trends in publication for policy-relevant information about children's health and to assess associations between the availability of reliable data and poverty.BACKGROUNDValid information about cause-specific child mortality and morbidity is an essential foundation for national and international health policy. We undertook a systematic review to investigate the geographical dispersion of and time trends in publication for policy-relevant information about children's health and to assess associations between the availability of reliable data and poverty.We identified data available on Jan 1, 2001, and published since 1980, for the major causes of morbidity and mortality in young children. Studies with relevant data were assessed against a set of inclusion criteria to identify those likely to provide unbiased estimates of the burden of childhood disease in the community.METHODSWe identified data available on Jan 1, 2001, and published since 1980, for the major causes of morbidity and mortality in young children. Studies with relevant data were assessed against a set of inclusion criteria to identify those likely to provide unbiased estimates of the burden of childhood disease in the community.Only 308 information units from more than 17,000 papers identified were regarded as possible unbiased sources for estimates of childhood disease burden. The geographical distribution of these information units revealed a pattern of small well-researched populations surrounded by large areas with little available information. No reliable population-based data were identified from many of the world's poorest countries, which account for about a third of all deaths of children worldwide. The number of new studies diminished over the last 10 years investigated.FINDINGSOnly 308 information units from more than 17,000 papers identified were regarded as possible unbiased sources for estimates of childhood disease burden. The geographical distribution of these information units revealed a pattern of small well-researched populations surrounded by large areas with little available information. No reliable population-based data were identified from many of the world's poorest countries, which account for about a third of all deaths of children worldwide. The number of new studies diminished over the last 10 years investigated.The number of population-based studies yielding estimates of burden of childhood disease from less developed countries was low. The decreasing trend over time suggests reductions in research investment in this sphere. Data are especially sparse from the world's least developed countries with the highest child mortality. Guidelines are needed for the conduct of burden-of-disease studies together with an international research policy that gives increased emphasis to global equity and coverage so that knowledge can be generated from all regions of the world.INTERPRETATIONThe number of population-based studies yielding estimates of burden of childhood disease from less developed countries was low. The decreasing trend over time suggests reductions in research investment in this sphere. Data are especially sparse from the world's least developed countries with the highest child mortality. Guidelines are needed for the conduct of burden-of-disease studies together with an international research policy that gives increased emphasis to global equity and coverage so that knowledge can be generated from all regions of the world.
Author Cousens, Simon
Rudan, Igor
Campbell, Harry
Lanata, Claudio F
Black, Robert E
Lawn, Joy
Carneiro, Ilona
Rowe, Alexander K
Schellenberg, Joanna A
Polašek, Ozren
Boschi-Pinto, Cynthia
Roca-Feltrer, Arantxa
Mendoza, Walter
Weber, Martin
Morris, Saul S
Bryce, Jennifer
Tomašković, Lana
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  organization: International Perinatal Care Unit, Institute of Child Health, London, UK
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  organization: Departments of Infectious and Tropical Diseases and Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
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  surname: Roca-Feltrer
  fullname: Roca-Feltrer, Arantxa
  organization: Departments of Infectious and Tropical Diseases and Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
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  givenname: Ilona
  surname: Carneiro
  fullname: Carneiro, Ilona
  organization: Departments of Infectious and Tropical Diseases and Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
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  givenname: Joanna A
  surname: Schellenberg
  fullname: Schellenberg, Joanna A
  organization: Departments of Infectious and Tropical Diseases and Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
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  givenname: Ozren
  surname: Polašek
  fullname: Polašek, Ozren
  organization: Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health, Andrija Stampar, University of Zagreb Medical School, Zagreb, Croatia
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  surname: Weber
  fullname: Weber, Martin
  organization: Child and Adolescent Health Department, WHO, Geneva, Switzerland
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  organization: Child and Adolescent Health Department, WHO, Geneva, Switzerland
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  givenname: Saul S
  surname: Morris
  fullname: Morris, Saul S
  organization: Europe, Middle East, and Americas Division, Department for International Development of the UK Government, London, UK
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  organization: Department of International Health, Johns Hopkins University, School of Hygiene and Public Health, Baltimore, MD, USA
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  givenname: Harry
  surname: Campbell
  fullname: Campbell, Harry
  email: Harry.Campbell@ed.ac.uk
  organization: Department of Community Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
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Issue 9476
Keywords Human
Health policy
Systematic review
Information
Child
Evidence-based medicine
Morbidity
Public health
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15954215 - Lancet. 2005 Jun 11-17;365(9476):1983.
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Snippet Valid information about cause-specific child mortality and morbidity is an essential foundation for national and international health policy. We undertook a...
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SubjectTerms Acute Disease
Biological and medical sciences
Child Mortality
Child, Preschool
Children & youth
Cost of Illness
Developed countries
Developing Countries - statistics & numerical data
Diarrhea - epidemiology
Diarrhea - mortality
Disease
General aspects
Geographical distribution
Health
Health Policy
Humans
Infant
Infant, Newborn
Infant, Newborn, Diseases - epidemiology
Infant, Newborn, Diseases - mortality
International policy
Malaria
Malaria, Falciparum - epidemiology
Malaria, Falciparum - mortality
Medical sciences
Morbidity
Mortality
Policy research
Population studies
Poverty
Respiratory Tract Infections - epidemiology
Respiratory Tract Infections - mortality
Systematic review
Vector-borne diseases
Title Gaps in policy-relevant information on burden of disease in children: a systematic review
URI https://www.clinicalkey.com/#!/content/1-s2.0-S0140673605666974
https://dx.doi.org/10.1016/S0140-6736(05)66697-4
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