Objectives, design and main findings until 2020 from the Rotterdam Study

The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical course, natural history and potential targets for intervention for chronic diseases in mid-life and late-life. The study focuses...

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Vydáno v:European journal of epidemiology Ročník 35; číslo 5; s. 483 - 517
Hlavní autoři: Ikram, M. Arfan, Brusselle, Guy, Ghanbari, Mohsen, Goedegebure, André, Ikram, M. Kamran, Kavousi, Maryam, Kieboom, Brenda C. T., Klaver, Caroline C. W., de Knegt, Robert J., Luik, Annemarie I., Nijsten, Tamar E. C., Peeters, Robin P., van Rooij, Frank J. A., Stricker, Bruno H., Uitterlinden, André G., Vernooij, Meike W., Voortman, Trudy
Médium: Journal Article
Jazyk:angličtina
Vydáno: Dordrecht Springer Netherlands 01.05.2020
Springer Nature B.V
Témata:
Cardiology
Cohort analysis
Epidemiology
Etiology
Infectious Diseases
Medicine
Medicine & Public Health
Oncology
Public Health
Respiratory diseases
Study Update
Dermatological diseases
Liver diseases
Endocrine diseases
Oncology
Psychiatric diseases
Epidemiologic methods
Ophthalmic diseases
Cancer and related diseases
Neurological diseases
Pharmacoepidemiology
Population imaging
Renal diseases
Genetic and molecular epidemiology
Otolaryngological diseases
Cohort study
Respiratory diseases
Biomarkers
Cardiovascular diseases
Nutrition and lifestyle epidemiology
ISSN:0393-2990, 1573-7284, 1573-7284
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Popis
Shrnutí:The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical course, natural history and potential targets for intervention for chronic diseases in mid-life and late-life. The study focuses on cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, otolaryngological, locomotor, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. Since 2016, the cohort is being expanded by persons aged 40 years and over. The findings of the Rotterdam Study have been presented in over 1700 research articles and reports. This article provides an update on the rationale and design of the study. It also presents a summary of the major findings from the preceding 3 years and outlines developments for the coming period.
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ISSN:0393-2990
1573-7284
1573-7284
DOI:10.1007/s10654-020-00640-5