Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile

Background The chaperone ClpB, a bacterial protein, is a conformational antigen-mimetic of α-melanocyte-stimulating hormone (α-MSH) implicated in body weight regulation in mice. We here investigated the potential associations of gut bacterial ClpB-like gene function with obesity status and gut micro...

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Bibliographic Details
Published in:	Microbiome Vol. 8; no. 1; pp. 59 - 10
Main Authors:	Arnoriaga-Rodríguez, María, Mayneris-Perxachs, Jordi, Burokas, Aurelijus, Pérez-Brocal, Vicente, Moya, Andrés, Portero-Otin, Manuel, Ricart, Wifredo, Maldonado, Rafael, Fernández-Real, José-Manuel
Format:	Journal Article
Language:	English
Published:	London BioMed Central 30.04.2020 Springer Nature B.V BMC
Subjects:	Acids Adult Aged Animals Bacteria Bacteria - classification Bacteria - isolation & purification Bacterial gene function Bacterial proteins Bioinformatics Biomedical and Life Sciences Biomedicine Body fat Body mass index Body weight Body weight gain Body weight regulation Case-Control Studies Cell cycle Clostridiaceae ClpB protein Cross-Sectional Studies Dual energy X-ray absorptiometry E coli Endopeptidase Clp - metabolism Energy Epitopes Fecal Microbiota Transplantation Feces Feces - microbiology Female Firmicutes Gastrointestinal Microbiome Humans Intestinal microflora Male Medical Microbiology Melanocyte-stimulating hormone Metabolism Metabolites Metabolomics Mice Mice, Inbred C57BL Microbial Ecology Microbial Genetics and Genomics Microbiology Microbiome Microbiota Middle Aged Obesity Obesity - microbiology Peptides Plasma Prevotellaceae Transplantation Virology Body weight regulation Obesity Microbiome Bacterial gene function
ISSN:	2049-2618, 2049-2618
Online Access:	Get full text
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