Metabolomics biomarkers to predict acamprosate treatment response in alcohol-dependent subjects

Precision medicine for alcohol use disorder (AUD) allows optimal treatment of the right patient with the right drug at the right time. Here, we generated multivariable models incorporating clinical information and serum metabolite levels to predict acamprosate treatment response. The sample of 120 p...

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Bibliographic Details
Published in:	Scientific reports Vol. 7; no. 1; pp. 2496 - 8
Main Authors:	Hinton, David J., Vázquez, Marely Santiago, Geske, Jennifer R., Hitschfeld, Mario J., Ho, Ada M. C., Karpyak, Victor M., Biernacka, Joanna M., Choi, Doo-Sup
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 31.05.2017 Nature Publishing Group Nature Portfolio
Subjects:	692/308/53/2423 692/53/2423 Acamprosate - administration & dosage Adult Alcohol Drinking - blood Alcohol Drinking - drug therapy Alcohol Drinking - epidemiology Alcohol Drinking - pathology Alcohol use Alcoholic beverages Alcoholism - blood Alcoholism - drug therapy Alcoholism - epidemiology Alcoholism - pathology Alcohols Biomarkers Biomarkers - blood Female Humanities and Social Sciences Humans Male Metabolites Metabolomics Middle Aged multidisciplinary Precision Medicine Prediction models Science Science (multidisciplinary) Treatment Outcome
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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