Statistical analysis of comparative tumor growth repeated measures experiments in the ovarian cancer patient derived xenograft (PDX) setting

Repeated measures studies are frequently performed in patient-derived xenograft (PDX) models to evaluate drug activity or compare effectiveness of cancer treatment regimens. Linear mixed effects regression models were used to perform statistical modeling of tumor growth data. Biologically plausible...

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Bibliographic Details
Published in:	Scientific reports Vol. 11; no. 1; pp. 8076 - 15
Main Authors:	Oberg, Ann L., Heinzen, Ethan P., Hou, Xiaonan, Al Hilli, Mariam M., Hurley, Rachel M., Wahner Hendrickson, Andrea E., Goergen, Krista M., Larson, Melissa C., Becker, Marc A., Eckel-Passow, Jeanette E., Maurer, Matthew J., Kaufmann, Scott H., Haluska, Paul, Weroha, S. John
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 13.04.2021 Nature Publishing Group Nature Portfolio
Subjects:	631/67 692/4028 Animals Cancer Female Humanities and Social Sciences Humans Linear Models Mathematical models Mice multidisciplinary Ovarian cancer Ovarian Neoplasms - pathology Regression analysis Science Science (multidisciplinary) Statistical analysis Statistical models Tumor Burden Tumors Within-subjects design Xenograft Model Antitumor Assays Xenografts
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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