Long noncoding RNA MALAT-1 is a new potential therapeutic target for castration resistant prostate cancer

To understand the role of MALAT-1 in prostate cancer we evaluated its expression in prostate cancer tissues and cell lines. We also studied the therapeutic effects of MALAT-1 silencing on castration resistant prostate cancer cells in vitro and in vivo. Quantitative reverse transcriptase-polymerase c...

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Vydané v:	The Journal of urology Ročník 190; číslo 6; s. 2278
Hlavní autori:	Ren, Shancheng, Liu, Yawei, Xu, Weidong, Sun, Yi, Lu, Ji, Wang, Fubo, Wei, Min, Shen, Jian, Hou, Jianguo, Gao, Xu, Xu, Chuanliang, Huang, Jiaoti, Zhao, Yi, Sun, Yinghao
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.12.2013
Predmet:	Animals Cell Cycle - genetics Humans Male Mice Prostatic Neoplasms, Castration-Resistant - drug therapy Prostatic Neoplasms, Castration-Resistant - genetics Prostatic Neoplasms, Castration-Resistant - metabolism RNA, Long Noncoding - biosynthesis RNA, Long Noncoding - genetics Tumor Cells, Cultured lncRNA RNA MALAT-1 siRNA-5 castration resistant prostate cancer M5 MALAT-1 siRNA-9 M9 reverse transcriptase-PCR LNCaP-AI RT-PCR long noncoding RNA CCK-8 small interfering LNCaP-androgen independent subtype human polymerase chain reaction PSA PBS MALAT1 long non-coding RNA prostate specific antigen Cell Counting Kit-8 phosphate buffered saline MALAT-1 prostatic neoplasms prostate antiandrogens metastasis associated in lung adenocarcinoma transcript 1 CRPC PCR
ISSN:	1527-3792, 1527-3792
On-line prístup:	Zistit podrobnosti o prístupe
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