Low cost DNA data storage using photolithographic synthesis and advanced information reconstruction and error correction

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. The current hamstring of DNA data storage systems—both in cost and speed—is synthesis. The key idea for breaking this bottleneck pursued in this work is to move beyond the low-error and expensive...

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Bibliographic Details
Published in:	Nature communications Vol. 11; no. 1; pp. 5345 - 10
Main Authors:	Antkowiak, Philipp L., Lietard, Jory, Darestani, Mohammad Zalbagi, Somoza, Mark M., Stark, Wendelin J., Heckel, Reinhard, Grass, Robert N.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 22.10.2020 Nature Publishing Group Nature Portfolio
Subjects:	49/23 631/553/2720 631/61/338/552 639/705/117 639/705/258 Algorithms Base Sequence Chemistry Techniques, Synthetic - methods Data recovery Data storage Deoxyribonucleic acid DNA DNA - chemical synthesis DNA - chemistry DNA - genetics DNA biosynthesis Error correction Gene Library Humanities and Social Sciences Information storage Information Storage and Retrieval - methods Light Monte Carlo Method multidisciplinary Oligonucleotide Array Sequence Analysis - methods Photochemical Processes Photolithography Reconstruction Science Science (multidisciplinary) Sequence Analysis, DNA Solid phase methods Solid phase synthesis Solid phases Storage systems
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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