Highly diverse flavobacterial phages isolated from North Sea spring blooms

It is generally recognized that phages are a mortality factor for their bacterial hosts. This could be particularly true in spring phytoplankton blooms, which are known to be closely followed by a highly specialized bacterial community. We hypothesized that phages modulate these dense heterotrophic...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:The ISME Journal Ročník 16; číslo 2; s. 555 - 568
Hlavní autoři: Bartlau, Nina, Wichels, Antje, Krohne, Georg, Adriaenssens, Evelien M., Heins, Anneke, Fuchs, Bernhard M., Amann, Rudolf, Moraru, Cristina
Médium: Journal Article
Jazyk:angličtina
Vydáno: London Nature Publishing Group UK 01.02.2022
Oxford University Press
Témata:
45/22
45/23
631/326/1321
631/326/171/1878
Bacteria
Bacteriophages - genetics
Biodegradation
Biomedical and Life Sciences
CRISPR
Ecology
Eutrophication
Evolutionary Biology
Flavobacteriaceae - genetics
Genera
Genomic analysis
Heterotrophic bacteria
Humans
Life Sciences
Metagenome
Microbial Ecology
Microbial Genetics and Genomics
Microbiology
Microorganisms
New families
New species
North Sea
Phages
Phytoplankton
Plankton
Polysaccharides
Saccharides
North Sea
ISSN:1751-7362, 1751-7370, 1751-7370
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Abstract It is generally recognized that phages are a mortality factor for their bacterial hosts. This could be particularly true in spring phytoplankton blooms, which are known to be closely followed by a highly specialized bacterial community. We hypothesized that phages modulate these dense heterotrophic bacteria successions following phytoplankton blooms. In this study, we focused on Flavobacteriia , because they are main responders during these blooms and have an important role in the degradation of polysaccharides. A cultivation-based approach was used, obtaining 44 lytic flavobacterial phages (flavophages), representing twelve new species from two viral realms. Taxonomic analysis allowed us to delineate ten new phage genera and ten new families, from which nine and four, respectively, had no previously cultivated representatives. Genomic analysis predicted various life styles and genomic replication strategies. A likely eukaryote-associated host habitat was reflected in the gene content of some of the flavophages. Detection in cellular metagenomes and by direct-plating showed that part of these phages were actively replicating in the environment during the 2018 spring bloom. Furthermore, CRISPR/Cas spacers and re-isolation during two consecutive years suggested that, at least part of the new flavophages are stable components of the microbial community in the North Sea. Together, our results indicate that these diverse flavophages have the potential to modulate their respective host populations.
AbstractList It is generally recognized that phages are a mortality factor for their bacterial hosts. This could be particularly true in spring phytoplankton blooms, which are known to be closely followed by a highly specialized bacterial community. We hypothesized that phages modulate these dense heterotrophic bacteria successions following phytoplankton blooms. In this study, we focused on Flavobacteriia, because they are main responders during these blooms and have an important role in the degradation of polysaccharides. A cultivation-based approach was used, obtaining 44 lytic flavobacterial phages (flavophages), representing twelve new species from two viral realms. Taxonomic analysis allowed us to delineate ten new phage genera and ten new families, from which nine and four, respectively, had no previously cultivated representatives. Genomic analysis predicted various life styles and genomic replication strategies. A likely eukaryote-associated host habitat was reflected in the gene content of some of the flavophages. Detection in cellular metagenomes and by direct-plating showed that part of these phages were actively replicating in the environment during the 2018 spring bloom. Furthermore, CRISPR/Cas spacers and re-isolation during two consecutive years suggested that, at least part of the new flavophages are stable components of the microbial community in the North Sea. Together, our results indicate that these diverse flavophages have the potential to modulate their respective host populations.It is generally recognized that phages are a mortality factor for their bacterial hosts. This could be particularly true in spring phytoplankton blooms, which are known to be closely followed by a highly specialized bacterial community. We hypothesized that phages modulate these dense heterotrophic bacteria successions following phytoplankton blooms. In this study, we focused on Flavobacteriia, because they are main responders during these blooms and have an important role in the degradation of polysaccharides. A cultivation-based approach was used, obtaining 44 lytic flavobacterial phages (flavophages), representing twelve new species from two viral realms. Taxonomic analysis allowed us to delineate ten new phage genera and ten new families, from which nine and four, respectively, had no previously cultivated representatives. Genomic analysis predicted various life styles and genomic replication strategies. A likely eukaryote-associated host habitat was reflected in the gene content of some of the flavophages. Detection in cellular metagenomes and by direct-plating showed that part of these phages were actively replicating in the environment during the 2018 spring bloom. Furthermore, CRISPR/Cas spacers and re-isolation during two consecutive years suggested that, at least part of the new flavophages are stable components of the microbial community in the North Sea. Together, our results indicate that these diverse flavophages have the potential to modulate their respective host populations.
It is generally recognized that phages are a mortality factor for their bacterial hosts. This could be particularly true in spring phytoplankton blooms, which are known to be closely followed by a highly specialized bacterial community. We hypothesized that phages modulate these dense heterotrophic bacteria successions following phytoplankton blooms. In this study, we focused on Flavobacteriia , because they are main responders during these blooms and have an important role in the degradation of polysaccharides. A cultivation-based approach was used, obtaining 44 lytic flavobacterial phages (flavophages), representing twelve new species from two viral realms. Taxonomic analysis allowed us to delineate ten new phage genera and ten new families, from which nine and four, respectively, had no previously cultivated representatives. Genomic analysis predicted various life styles and genomic replication strategies. A likely eukaryote-associated host habitat was reflected in the gene content of some of the flavophages. Detection in cellular metagenomes and by direct-plating showed that part of these phages were actively replicating in the environment during the 2018 spring bloom. Furthermore, CRISPR/Cas spacers and re-isolation during two consecutive years suggested that, at least part of the new flavophages are stable components of the microbial community in the North Sea. Together, our results indicate that these diverse flavophages have the potential to modulate their respective host populations.
It is generally recognized that phages are a mortality factor for their bacterial hosts. This could be particularly true in spring phytoplankton blooms, which are known to be closely followed by a highly specialized bacterial community. We hypothesized that phages modulate these dense heterotrophic bacteria successions following phytoplankton blooms. In this study, we focused on Flavobacteriia, because they are main responders during these blooms and have an important role in the degradation of polysaccharides. A cultivation-based approach was used, obtaining 44 lytic flavobacterial phages (flavophages), representing twelve new species from two viral realms. Taxonomic analysis allowed us to delineate ten new phage genera and ten new families, from which nine and four, respectively, had no previously cultivated representatives. Genomic analysis predicted various life styles and genomic replication strategies. A likely eukaryote-associated host habitat was reflected in the gene content of some of the flavophages. Detection in cellular metagenomes and by direct-plating showed that part of these phages were actively replicating in the environment during the 2018 spring bloom. Furthermore, CRISPR/Cas spacers and re-isolation during two consecutive years suggested that, at least part of the new flavophages are stable components of the microbial community in the North Sea. Together, our results indicate that these diverse flavophages have the potential to modulate their respective host populations.
Author Heins, Anneke
Wichels, Antje
Adriaenssens, Evelien M.
Krohne, Georg
Bartlau, Nina
Fuchs, Bernhard M.
Moraru, Cristina
Amann, Rudolf
Author_xml – sequence: 1
  givenname: Nina
  orcidid: 0000-0002-7803-5444
  surname: Bartlau
  fullname: Bartlau, Nina
  organization: Max Planck Institute for Marine Microbiology
– sequence: 2
  givenname: Antje
  surname: Wichels
  fullname: Wichels, Antje
  organization: Alfred Wegener Institute Helmholtz Center for Polar and Marine Research, Biologische Anstalt Helgoland
– sequence: 3
  givenname: Georg
  surname: Krohne
  fullname: Krohne, Georg
  organization: Imaging Core Facility, Biocenter, University of Würzburg
– sequence: 4
  givenname: Evelien M.
  orcidid: 0000-0003-4826-5406
  surname: Adriaenssens
  fullname: Adriaenssens, Evelien M.
  organization: Quadram Institute Bioscience
– sequence: 5
  givenname: Anneke
  surname: Heins
  fullname: Heins, Anneke
  organization: Max Planck Institute for Marine Microbiology
– sequence: 6
  givenname: Bernhard M.
  orcidid: 0000-0001-9828-1290
  surname: Fuchs
  fullname: Fuchs, Bernhard M.
  organization: Max Planck Institute for Marine Microbiology
– sequence: 7
  givenname: Rudolf
  orcidid: 0000-0002-0846-7372
  surname: Amann
  fullname: Amann, Rudolf
  email: ramann@mpi-bremen.de
  organization: Max Planck Institute for Marine Microbiology
– sequence: 8
  givenname: Cristina
  orcidid: 0000-0002-5375-5437
  surname: Moraru
  fullname: Moraru, Cristina
  email: liliana.cristina.moraru@uni-oldenburg.de
  organization: Institute for Chemistry and Biology of the Marine Environment, University of Oldenburg
BackLink https://www.ncbi.nlm.nih.gov/pubmed/34475519$$D View this record in MEDLINE/PubMed
BookMark eNp9kUtP3DAUhS1EVR7tH2CBLLHpJsXvxwYJIVpaobKgXVtOcjNj5MSDnRmJf99MAxRYsLpXuuccffY5QLtDGgChI0q-UsLNaRGUW1URRitCidWV2EH7VEtaaa7J7vOu2B46KOWOEKmV0h_RHhdCS0ntPvp5FRbL-IDbsIFcAHfRb1LtmxFy8BGvln4BBYeSoh-hxV1OPf6V8rjEt-BxWeUwLHAdU-rLJ_Sh87HA58d5iP58u_x9cVVd33z_cXF-XTVSkLHyrCGWt61qvbVQ10ZQClowBTXTivnOKmlUx6m3bUfraSedEtQQWhPZNpYforM5d7Wue2gbGMbso5tQep8fXPLBvb4MYekWaeOM1soQMQV8eQzI6X4NZXR9KA3E6AdI6-KYVJYbZs1WevJGepfWeZie55hiVDCpjZxUxy-JnlGevnkSmFnQ5FRKhs41YfRjSFvAEB0lbtuomxt1U6PuX6NuS8DeWJ_S3zXx2TQXBPk_9juuv8WkszU
CitedBy_id crossref_primary_10_1002_lno_12773
crossref_primary_10_1111_1462_2920_16505
crossref_primary_10_3390_biom13010110
crossref_primary_10_1128_msphere_00458_24
crossref_primary_10_1186_s40793_024_00637_7
crossref_primary_10_3389_fmicb_2023_1161265
crossref_primary_10_1038_s41467_025_57500_7
crossref_primary_10_1038_s43705_023_00317_6
crossref_primary_10_1128_aem_00367_24
crossref_primary_10_1128_aem_00623_23
crossref_primary_10_1128_msystems_00192_22
crossref_primary_10_1186_s40168_024_01902_0
crossref_primary_10_1038_s41467_024_48301_5
crossref_primary_10_3389_fmars_2022_834337
crossref_primary_10_3389_fmicb_2023_1295193
crossref_primary_10_3390_ijms241813980
crossref_primary_10_1016_j_scitotenv_2023_163609
crossref_primary_10_1186_s40168_023_01607_w
crossref_primary_10_3389_fmars_2023_1248754
crossref_primary_10_3390_microorganisms12010118
crossref_primary_10_3390_v15102038
crossref_primary_10_3389_fmicb_2022_853973
crossref_primary_10_1093_ismejo_wrae083
crossref_primary_10_1128_msystems_01211_22
crossref_primary_10_3390_v17030365
crossref_primary_10_1016_j_watbs_2022_100062
crossref_primary_10_1016_j_tim_2024_07_003
crossref_primary_10_1038_s43705_023_00307_8
crossref_primary_10_1128_msystems_00568_24
crossref_primary_10_1128_msystems_00949_23
crossref_primary_10_1016_j_watres_2024_122253
crossref_primary_10_1111_1462_2920_16670
crossref_primary_10_3389_fmicb_2022_863686
crossref_primary_10_3390_pathogens12010101
crossref_primary_10_1016_j_mib_2022_102229
crossref_primary_10_1111_1462_2920_16675
Cites_doi 10.2307/1313569
10.1089/cmb.2012.0021
10.1016/j.cell.2018.10.059
10.1007/s12275-008-0098-y
10.1007/s00792-003-0334-7
10.3389/fevo.2019.00174
10.1038/nature17193
10.1128/mBio.00638-19
10.1038/ismej.2013.19
10.1038/ismej.2015.48
10.1007/s12237-009-9228-y
10.1038/340467a0
10.1007/BF00388798
10.1016/j.mib.2017.04.010
10.1038/s41396-018-0242-6
10.1128/AEM.06580-11
10.1128/JVI.01396-12
10.1128/AEM.03114-15
10.1007/BF03051518
10.1038/s41564-019-0628-x
10.3390/v13030506
10.1111/1462-2920.14261
10.1128/AEM.64.6.2051-2060.1998
10.1093/nar/gky467
10.1016/j.syapm.2008.08.003
10.3390/md10040834
10.4319/lo.2000.45.6.1320
10.1128/AEM.01399-07
10.1128/JVI.01875-14
10.1128/AEM.70.11.6753-6766.2004
10.1038/nmeth.4285
10.1111/j.0022-3646.1996.00506.x
10.3389/fmicb.2014.00506
10.1038/s41587-020-0718-6
10.1038/s41396-020-0601-y
10.1016/j.cell.2019.03.040
10.1007/BF00166813
10.3389/fmicb.2018.03301
10.5670/oceanog.2007.58
10.1128/MMBR.00061-19
10.3354/ame018275
10.1093/sysbio/syz036
10.1093/molbev/msx281
10.1038/343060a0
10.3390/md13095993
10.1111/j.1462-2920.2010.02280.x
10.1128/AEM.64.2.535-542.1998
10.1093/nar/gkh293
10.1073/pnas.1115467109
10.1186/s40793-015-0076-z
10.1093/bioinformatics/btx157
10.7554/eLife.11888
10.1038/nature19366
10.1111/1751-7915.12076
10.1038/ismej.2017.26
10.1038/ncomms15892
10.1016/j.coviro.2013.06.010
10.1093/nar/gky1127
10.1016/j.tim.2012.10.005
10.3354/meps092099
10.1038/ncomms15955
10.1128/mSphere.00359-16
10.1128/aem.56.3.583-589.1990
10.1099/jgv.0.001110
10.1038/347467a0
10.3390/v12111268
10.1007/s00253-017-8224-6
10.1093/molbev/msu300
10.1371/journal.pgen.1003987
10.1126/science.1218344
10.1093/nar/gky425
10.1111/1462-2920.12466
10.1093/bioinformatics/btl117
10.1007/s10126-011-9388-1
10.1038/s41396-019-0476-y
10.1128/JVI.01327-12
10.1038/nature11602
10.1128/mBio.00805-16
10.1093/bioinformatics/btx440
10.1093/bioinformatics/btx383
10.1186/1471-2105-10-421
10.1371/journal.pone.0015388
10.1038/s41396-018-0243-5
10.1093/nar/gkh340
10.1073/pnas.50.6.1043
10.1007/s00253-015-7247-0
10.1128/AEM.64.11.4128-4133.1998
10.1007/s10152-004-0189-z
10.1038/s41396-019-0362-7
10.1093/bioinformatics/btu033
10.1007/978-1-60327-565-1_7
10.1016/B978-0-12-065602-8.50009-1
ContentType Journal Article
Copyright The Author(s) 2021
2021. The Author(s).
The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: The Author(s) 2021
– notice: 2021. The Author(s).
– notice: The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID C6C
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7QL
7SN
7ST
7T7
7TM
7X7
7XB
88E
8FD
8FE
8FH
8FI
8FJ
8FK
ABUWG
AEUYN
AFKRA
ATCPS
AZQEC
BBNVY
BENPR
BHPHI
C1K
CCPQU
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
HCIFZ
K9.
LK8
M0S
M1P
M7N
M7P
P64
PATMY
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQQKQ
PQUKI
PRINS
PYCSY
SOI
7X8
5PM
DOI 10.1038/s41396-021-01097-4
DatabaseName Springer Nature OA Free Journals
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Bacteriology Abstracts (Microbiology B)
Ecology Abstracts
Environment Abstracts
Industrial and Applied Microbiology Abstracts (Microbiology A)
Nucleic Acids Abstracts
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Technology Research Database
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest One Sustainability
ProQuest Central UK/Ireland
Agricultural & Environmental Science Collection
ProQuest Central Essentials - QC
Biological Science Collection
ProQuest Central
Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Central
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
Biological Sciences
ProQuest Health & Medical Collection
Medical Database
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Biotechnology and BioEngineering Abstracts
Environmental Science Database
ProQuest Central Premium
ProQuest One Academic (New)
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic (retired)
ProQuest One Academic UKI Edition
ProQuest Central China
Environmental Science Collection
Environment Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
ProQuest Central Student
Technology Research Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
Nucleic Acids Abstracts
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Central China
Environmental Sciences and Pollution Management
ProQuest Central
ProQuest One Applied & Life Sciences
ProQuest One Sustainability
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Health & Medical Research Collection
Agricultural & Environmental Science Collection
Biological Science Collection
Industrial and Applied Microbiology Abstracts (Microbiology A)
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
Ecology Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Environmental Science Collection
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
Environmental Science Database
Engineering Research Database
ProQuest One Academic
Environment Abstracts
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic


CrossRef
MEDLINE
ProQuest Central Student
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
Ecology
EISSN 1751-7370
EndPage 568
ExternalDocumentID PMC8776804
34475519
10_1038_s41396_021_01097_4
Genre Research Support, Non-U.S. Gov't
Journal Article
GeographicLocations North Sea
GeographicLocations_xml – name: North Sea
GrantInformation_xml – fundername: Deutsche Forschungsgemeinschaft (German Research Foundation)
  grantid: INST 184/157-1 FUGG; FOR2406; FOR2406; FOR2406; FOR2406
  funderid: https://doi.org/10.13039/501100001659
– fundername: BBSRC Institute Strategic Programme Gut Microbes and Health BB/R012490/1.
– fundername: Biotechnology and Biological Sciences Research Council
  grantid: BBS/E/F/000PR10356
– fundername: Biotechnology and Biological Sciences Research Council
  grantid: BBS/E/F/000PR10353
– fundername: ;
– fundername: ;
  grantid: INST 184/157-1 FUGG; FOR2406; FOR2406; FOR2406; FOR2406
GroupedDBID ---
-Q-
0R~
123
29J
39C
3V.
4.4
406
53G
70F
7X7
7XC
88E
8FE
8FH
8FI
8FJ
AAHBH
AANZL
AAZLF
ABAKF
ABAWZ
ABDBF
ABEJV
ABGNP
ABJNI
ABLJU
ABUWG
ABXVV
ACGFS
ACKTT
ACPRK
ACRQY
ACUHS
ACZOJ
ADBBV
ADHDB
AEFQL
AEJRE
AENEX
AEUYN
AEVLU
AEXYK
AFKRA
AFRAH
AFSHS
AGAYW
AGHAI
AGQEE
AHMBA
AHSBF
AILAN
AJRNO
ALFFA
ALMA_UNASSIGNED_HOLDINGS
AMNDL
AMYLF
AOIJS
ASPBG
ATCPS
AVWKF
AXYYD
AZFZN
BBNVY
BENPR
BHPHI
BKKNO
BPHCQ
BVXVI
C6C
CCPQU
CS3
DNIVK
DPUIP
DU5
EBS
EDH
EE.
EIOEI
EJD
EMOBN
ESX
F5P
FDQFY
FEDTE
FERAY
FIZPM
FSGXE
FYUFA
HCIFZ
HMCUK
HVGLF
HYE
HZ~
I-F
IWAJR
JSO
KQ8
LK8
M1P
M7P
MM.
NAO
NQJWS
O9-
OK1
PATMY
PQQKQ
PROAC
PSQYO
PYCSY
RNT
RNTTT
ROX
RPM
SNX
SNYQT
SOHCF
SRMVM
SV3
SWTZT
TAOOD
TBHMF
TDRGL
TOX
TR2
TSG
TUS
UKHRP
~02
~8M
AAYXX
ACSTC
AFFHD
AYFIA
CITATION
EBLON
H13
JZLTJ
PHGZM
PHGZT
PJZUB
PPXIY
PQGLB
CGR
CUY
CVF
ECGQY
ECM
EIF
GROUPED_DOAJ
NPM
7QL
7SN
7ST
7T7
7TM
7XB
8FD
8FK
AZQEC
C1K
DWQXO
FR3
GNUQQ
K9.
M7N
P64
PKEHL
PQEST
PQUKI
PRINS
SOI
7X8
PUEGO
5PM
ID FETCH-LOGICAL-c540t-a2c093dd6da99ebb8411e7426eb2762af96586f31a9df1b5860f641801b05dc93
IEDL.DBID M7P
ISICitedReferencesCount 40
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000692061100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 1751-7362
1751-7370
IngestDate Tue Nov 04 01:57:50 EST 2025
Fri Sep 05 12:06:23 EDT 2025
Sat Nov 29 15:00:34 EST 2025
Mon Jul 21 06:03:09 EDT 2025
Sat Nov 29 02:23:23 EST 2025
Tue Nov 18 22:43:10 EST 2025
Fri Feb 21 02:40:15 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Language English
License https://creativecommons.org/licenses/by/4.0
2021. The Author(s).
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c540t-a2c093dd6da99ebb8411e7426eb2762af96586f31a9df1b5860f641801b05dc93
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ORCID 0000-0001-9828-1290
0000-0002-0846-7372
0000-0003-4826-5406
0000-0002-7803-5444
0000-0002-5375-5437
OpenAccessLink https://pubmed.ncbi.nlm.nih.gov/PMC8776804
PMID 34475519
PQID 2621425785
PQPubID 536304
PageCount 14
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_8776804
proquest_miscellaneous_2569382984
proquest_journals_2621425785
pubmed_primary_34475519
crossref_citationtrail_10_1038_s41396_021_01097_4
crossref_primary_10_1038_s41396_021_01097_4
springer_journals_10_1038_s41396_021_01097_4
PublicationCentury 2000
PublicationDate 2022-02-01
PublicationDateYYYYMMDD 2022-02-01
PublicationDate_xml – month: 02
  year: 2022
  text: 2022-02-01
  day: 01
PublicationDecade 2020
PublicationPlace London
PublicationPlace_xml – name: London
– name: England
PublicationSubtitle Multidisciplinary Journal of Microbial Ecology
PublicationTitle The ISME Journal
PublicationTitleAbbrev ISME J
PublicationTitleAlternate ISME J
PublicationYear 2022
Publisher Nature Publishing Group UK
Oxford University Press
Publisher_xml – name: Nature Publishing Group UK
– name: Oxford University Press
References Mizuno, Rodriguez-Valera, Kimes, Ghai (CR46) 2013; 9
Hoang, Chernomor, von Haeseler, Minh, Vinh (CR58) 2017; 35
Krupovic (CR77) 2013; 3
Pires, Oliveira, Melo, Sillankorva, Azeredo (CR91) 2016; 100
Touchon, Moura de Sousa, Rocha (CR8) 2017; 38
Dziewit, Oscik, Bartosik, Radlinska (CR79) 2014; 88
Camacho, Coulouris, Avagyan, Ma, Papadopoulos, Bealer (CR61) 2009; 10
Wiltshire, Kraberg, Bartsch, Boersma, Franke, Freund (CR98) 2010; 33
Stamatakis (CR65) 2014; 30
Borriss, Helmke, Hanschke, Schweder (CR39) 2003; 7
Nissimov, Vandzura, Johns, Natale, Haramaty, Bidle (CR11) 2018; 20
Bischoff, Bunk, Meier-Kolthoff, Spröer, Poehlein, Dogs (CR28) 2019; 13
Gonzalez, Sherr, Sherr (CR26) 1990; 56
Martinez-Hernandez, Fornas, Lluesma Gomez, Bolduc, de la Cruz Peña, Martínez (CR50) 2017; 8
Silpe, Bassler (CR93) 2019; 10
Latka, Maciejewska, Majkowska-Skrobek, Briers, Drulis-Kawa (CR90) 2017; 101
Ludwig, Strunk, Westram, Richter, Meier, Yadhukumar (CR66) 2004; 32
Avcı, Krüger, Fuchs, Teeling, Amann (CR85) 2020; 14
Fuller, Wilson, Joint, Mann (CR34) 1998; 64
Nishimura, Watai, Honda, Mihara, Omae, Roux (CR47) 2017; 2
Gerdts, Wichels, Döpke, Klings, Gunkel, Schütt (CR15) 2004; 58
Reintjes, Arnosti, Fuchs, Amann (CR24) 2017; 11
Suttle (CR3) 1994; 28
Suttle, Chan, Cottrell (CR36) 1990; 347
Proctor, Fuhrman (CR35) 1990; 343
Wilhelm, Suttle (CR5) 1999; 49
Kappelmann, Krüger, Hehemann, Harder, Markert, Unfried (CR86) 2019; 13
Moraru, Varsani, Kropinski (CR55) 2020; 12
Roux, Brum, Dutilh, Sunagawa, Duhaime, Loy (CR14) 2016; 537
Thingstad (CR4) 2000; 45
Proctor, Fuhrman (CR1) 1990; 343
Pinhassi, Sala, Havskum, Peters, Guadayol, Malits (CR16) 2004; 70
Sullivan, Huang, Ignacio-Espinoza, Berlin, Kelly, Weigele (CR43) 2010; 12
Meier-Kolthoff, Göker (CR53) 2017; 33
Couvin, Bernheim, Toffano-Nioche, Touchon, Michalik, Néron (CR68) 2018; 46
CR51
Forterre, Soler, Krupovic, Marguet, Ackermann (CR69) 2013; 21
Ignacio-Espinoza, Ahlgren, Fuhrman (CR97) 2020; 5
Montaño, Pigli, Rice (CR76) 2012; 491
Chan, Millard, Mann, Schäfer (CR29) 2014; 5
Mizuno, Ghai, Saghaï, López-García, Rodriguez-Valera (CR45) 2016; 7
Breitbart, Thompson, Suttle, Sullivan (CR6) 2007; 20
Labonté, Swan, Poulos, Luo, Koren, Hallam (CR49) 2015; 9
Peplies, Kottmann, Ludwig, Glöckner (CR67) 2008; 31
Paez-Espino, Roux, Chen, Palaniappan, Ratner, Chu (CR48) 2019; 47
Nayfach, Roux, Seshadri, Udwary, Varghese, Schulz (CR63) 2020; 39
Silpe, Bassler (CR94) 2019; 176
CR60
Aiewsakun, Adriaenssens, Lavigne, Kropinski, Simmonds (CR54) 2018; 99
Edgar (CR56) 2004; 32
Teeling, Fuchs, Bennke, Kruger, Chafee, Kappelmann (CR19) 2016; 5
Galiez, Siebert, Enault, Vincent, Söding (CR62) 2017; 33
Holmfeldt, Odić, Sullivan, Middelboe, Riemann (CR37) 2012; 78
Barylski, Enault, Dutilh, Schuller, Edwards, Gillis (CR72) 2019; 69
CR75
Bižić-Ionescu, Zeder, Ionescu, Orlić, Fuchs, Grossart (CR92) 2015; 17
Kang, Jang, Cho (CR38) 2015; 10
Khotimchenko, Khozhaenko, Kovalev, Khotimchenko (CR82) 2012; 10
Wohlkönig, Huet, Looze, Wintjens (CR78) 2010; 5
Nagasaki (CR70) 2008; 46
Turner, Kropinski, Adriaenssens (CR73) 2021; 13
Krüger, Chafee, Francis, Glavina del Rio, Becher, Schweder (CR84) 2019; 13
Kang, Jang, Cho (CR42) 2012; 86
Steward, Wikner, Cochlan, Smith, Azam (CR2) 1992; 6
Shimodaira, Terada (CR99) 2019; 7
Coutinho, Silveira, Gregoracci, Thompson, Edwards, Brussaard (CR7) 2017; 8
Gügi, Le Costaouec, Burel, Lerouge, Helbert, Bardor (CR20) 2015; 13
Holmfeldt, Middelboe, Nybroe, Riemann (CR27) 2007; 73
Kang, Kang, Cho (CR41) 2012; 86
CR89
Teeling, Fuchs, Becher, Klockow, Gardebrecht, Bennke (CR18) 2012; 336
Rodriguez-R, Gunturu, Harvey, Rosselló-Mora, Tiedje, Cole (CR64) 2018; 46
Maleki, Almaas, Zotchev, Valla, Ertesvåg (CR87) 2016; 82
Suzuki, Shimodaira (CR100) 2006; 22
Wilson, Carr, Mann (CR33) 1996; 32
Desikachary, Dweltz (CR81) 1961; 53
Souza, Almeida, Colwell, Rivera (CR80) 2011; 13
Bergh, BØrsheim, Bratbak, Heldal (CR12) 1989; 340
Sabehi, Shaulov, Silver, Yanai, Harel, Lindell (CR31) 2012; 109
Needham, Chow, Cram, Sachdeva, Parada, Fuhrman (CR96) 2013; 7
CR10
Haug, Myklestad (CR21) 1976; 34
Singh, Adams, Brown (CR88) 2019; 9
CR95
Koonin, Dolja, Krupovic, Varsani, Wolf, Yutin (CR71) 2020; 84
Knowles, Silveira, Bailey, Barott, Cantu, Cobián-Güemes (CR9) 2016; 531
Simon, Glöckner, Amann (CR17) 1999; 18
Unfried, Becker, Robb, Hehemann, Markert, Heiden (CR23) 2018; 12
Suttle, Chan (CR32) 1993; 92
Wichels, Biel, Gelderblom, Brinkhoff, Muyzer, Schütt (CR30) 1998; 64
Gregory, Zayed, Conceição-Neto, Temperton, Bolduc, Alberti (CR13) 2019; 177
CR25
Bankevich, Nurk, Antipov, Gurevich, Dvorkin, Kulikov (CR44) 2012; 19
Nguyen, Schmidt, von Haeseler, Minh (CR57) 2014; 32
CR22
Jiang, Kellogg, Paul (CR40) 1998; 64
Hay, Ur Rehman, Moradali, Wang, Rehm (CR83) 2013; 6
Taylor (CR74) 1963; 50
Nishimura, Yoshida, Kuronishi, Uehara, Ogata, Goto (CR52) 2017; 33
Kalyaanamoorthy, Minh, Wong, von Haeseler, Jermiin (CR59) 2017; 14
Nagasaki (2024011018032905700_CR70) 2008; 46
Holmfeldt (2024011018032905700_CR37) 2012; 78
2024011018032905700_CR10
Bergh (2024011018032905700_CR12) 1989; 340
Unfried (2024011018032905700_CR23) 2018; 12
Simon (2024011018032905700_CR17) 1999; 18
Reintjes (2024011018032905700_CR24) 2017; 11
Gonzalez (2024011018032905700_CR26) 1990; 56
Proctor (2024011018032905700_CR35) 1990; 343
Avcı (2024011018032905700_CR85) 2020; 14
Wilhelm (2024011018032905700_CR5) 1999; 49
Labonté (2024011018032905700_CR49) 2015; 9
Fuller (2024011018032905700_CR34) 1998; 64
Gregory (2024011018032905700_CR13) 2019; 177
Edgar (2024011018032905700_CR56) 2004; 32
2024011018032905700_CR89
Montaño (2024011018032905700_CR76) 2012; 491
Needham (2024011018032905700_CR96) 2013; 7
Suttle (2024011018032905700_CR32) 1993; 92
Ignacio-Espinoza (2024011018032905700_CR97) 2020; 5
Chan (2024011018032905700_CR29) 2014; 5
Martinez-Hernandez (2024011018032905700_CR50) 2017; 8
Kang (2024011018032905700_CR42) 2012; 86
Suttle (2024011018032905700_CR3) 1994; 28
Kang (2024011018032905700_CR38) 2015; 10
Turner (2024011018032905700_CR73) 2021; 13
Suttle (2024011018032905700_CR36) 1990; 347
Nishimura (2024011018032905700_CR52) 2017; 33
Kalyaanamoorthy (2024011018032905700_CR59) 2017; 14
Koonin (2024011018032905700_CR71) 2020; 84
Maleki (2024011018032905700_CR87) 2016; 82
Wilson (2024011018032905700_CR33) 1996; 32
Silpe (2024011018032905700_CR94) 2019; 176
Touchon (2024011018032905700_CR8) 2017; 38
Steward (2024011018032905700_CR2) 1992; 6
Nayfach (2024011018032905700_CR63) 2020; 39
Breitbart (2024011018032905700_CR6) 2007; 20
Proctor (2024011018032905700_CR1) 1990; 343
Bowman (2024011018032905700_CR95) 2006
Mizuno (2024011018032905700_CR45) 2016; 7
Krüger (2024011018032905700_CR84) 2019; 13
Meier-Kolthoff (2024011018032905700_CR53) 2017; 33
2024011018032905700_CR60
Sabehi (2024011018032905700_CR31) 2012; 109
Teeling (2024011018032905700_CR18) 2012; 336
Moraru (2024011018032905700_CR51) 2021; 2021.06.14.448304
Coutinho (2024011018032905700_CR7) 2017; 8
Sullivan (2024011018032905700_CR43) 2010; 12
Krupovic (2024011018032905700_CR77) 2013; 3
Dziewit (2024011018032905700_CR79) 2014; 88
Souza (2024011018032905700_CR80) 2011; 13
Gügi (2024011018032905700_CR20) 2015; 13
Nguyen (2024011018032905700_CR57) 2014; 32
Bižić-Ionescu (2024011018032905700_CR92) 2015; 17
Bankevich (2024011018032905700_CR44) 2012; 19
Paez-Espino (2024011018032905700_CR48) 2019; 47
Couvin (2024011018032905700_CR68) 2018; 46
Hoang (2024011018032905700_CR58) 2017; 35
Nissimov (2024011018032905700_CR11) 2018; 20
Nishimura (2024011018032905700_CR47) 2017; 2
Rodriguez-R (2024011018032905700_CR64) 2018; 46
Forterre (2024011018032905700_CR69) 2013; 21
Barylski (2024011018032905700_CR72) 2019; 69
Moraru (2024011018032905700_CR55) 2020; 12
Teeling (2024011018032905700_CR19) 2016; 5
Singh (2024011018032905700_CR88) 2019; 9
Casjens (2024011018032905700_CR75) 2009
Bischoff (2024011018032905700_CR28) 2019; 13
Aiewsakun (2024011018032905700_CR54) 2018; 99
Pires (2024011018032905700_CR91) 2016; 100
Haug (2024011018032905700_CR21) 1976; 34
Roux (2024011018032905700_CR14) 2016; 537
Wichels (2024011018032905700_CR30) 1998; 64
Galiez (2024011018032905700_CR62) 2017; 33
Mizuno (2024011018032905700_CR46) 2013; 9
Latka (2024011018032905700_CR90) 2017; 101
Desikachary (2024011018032905700_CR81) 1961; 53
Thingstad (2024011018032905700_CR4) 2000; 45
Ludwig (2024011018032905700_CR66) 2004; 32
Borriss (2024011018032905700_CR39) 2003; 7
Hay (2024011018032905700_CR83) 2013; 6
Stamatakis (2024011018032905700_CR65) 2014; 30
Camacho (2024011018032905700_CR61) 2009; 10
Suzuki (2024011018032905700_CR100) 2006; 22
Painter (2024011018032905700_CR22) 1983
Wiltshire (2024011018032905700_CR98) 2010; 33
Jiang (2024011018032905700_CR40) 1998; 64
Kang (2024011018032905700_CR41) 2012; 86
Kappelmann (2024011018032905700_CR86) 2019; 13
2024011018032905700_CR25
Shimodaira (2024011018032905700_CR99) 2019; 7
Taylor (2024011018032905700_CR74) 1963; 50
Wohlkönig (2024011018032905700_CR78) 2010; 5
Khotimchenko (2024011018032905700_CR82) 2012; 10
Gerdts (2024011018032905700_CR15) 2004; 58
Silpe (2024011018032905700_CR93) 2019; 10
Holmfeldt (2024011018032905700_CR27) 2007; 73
Peplies (2024011018032905700_CR67) 2008; 31
Knowles (2024011018032905700_CR9) 2016; 531
Pinhassi (2024011018032905700_CR16) 2004; 70
References_xml – volume: 49
  start-page: 781
  year: 1999
  end-page: 8
  ident: CR5
  article-title: Viruses and nutrient cycles in the sea: viruses play critical roles in the structure and function of aquatic food webs
  publication-title: BioScience.
  doi: 10.2307/1313569
– ident: CR22
– volume: 19
  start-page: 455
  year: 2012
  end-page: 77
  ident: CR44
  article-title: SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing
  publication-title: J Comput Biol
  doi: 10.1089/cmb.2012.0021
– volume: 176
  start-page: 268
  year: 2019
  end-page: 80.e13
  ident: CR94
  article-title: A host-produced quorum-sensing autoinducer controls a phage lysis-lysogeny decision
  publication-title: Cell.
  doi: 10.1016/j.cell.2018.10.059
– ident: CR51
– volume: 46
  start-page: 235
  year: 2008
  end-page: 43
  ident: CR70
  article-title: Dinoflagellates, diatoms, and their viruses
  publication-title: J Microbiol
  doi: 10.1007/s12275-008-0098-y
– volume: 7
  start-page: 377
  year: 2003
  end-page: 84
  ident: CR39
  article-title: Isolation and characterization of marine psychrophilic phage-host systems from Arctic sea ice
  publication-title: Extremophiles.
  doi: 10.1007/s00792-003-0334-7
– volume: 7
  start-page: 174
  year: 2019
  ident: CR99
  article-title: Selective inference for testing trees and edges in phylogenetics
  publication-title: Front Ecol Evolut
  doi: 10.3389/fevo.2019.00174
– volume: 531
  start-page: 466
  year: 2016
  end-page: 70
  ident: CR9
  article-title: Lytic to temperate switching of viral communities
  publication-title: Nature.
  doi: 10.1038/nature17193
– volume: 10
  start-page: e00638
  year: 2019
  end-page: 19
  ident: CR93
  article-title: Phage-encoded LuxR-type receptors responsive to host-produced bacterial quorum-sensing autoinducers
  publication-title: mBio.
  doi: 10.1128/mBio.00638-19
– ident: CR25
– volume: 7
  start-page: 1274
  year: 2013
  end-page: 85
  ident: CR96
  article-title: Short-term observations of marine bacterial and viral communities: patterns, connections and resilience
  publication-title: ISME J
  doi: 10.1038/ismej.2013.19
– volume: 9
  start-page: 2386
  year: 2015
  end-page: 99
  ident: CR49
  article-title: Single-cell genomics-based analysis of virus–host interactions in marine surface bacterioplankton
  publication-title: ISME J
  doi: 10.1038/ismej.2015.48
– volume: 33
  start-page: 295
  year: 2010
  end-page: 310
  ident: CR98
  article-title: Helgoland Roads, North Sea: 45 years of change
  publication-title: Estuaries Coasts
  doi: 10.1007/s12237-009-9228-y
– volume: 340
  start-page: 467
  year: 1989
  end-page: 8
  ident: CR12
  article-title: High abundance of viruses found in aquatic environments
  publication-title: Nature.
  doi: 10.1038/340467a0
– volume: 34
  start-page: 217
  year: 1976
  end-page: 22
  ident: CR21
  article-title: Polysaccharides of marine diatoms with special reference to species
  publication-title: Mar Biol
  doi: 10.1007/BF00388798
– volume: 38
  start-page: 66
  year: 2017
  end-page: 73
  ident: CR8
  article-title: Embracing the enemy: the diversification of microbial gene repertoires by phage-mediated horizontal gene transfer
  publication-title: Curr Opin Microbiol
  doi: 10.1016/j.mib.2017.04.010
– volume: 13
  start-page: 76
  year: 2019
  end-page: 91
  ident: CR86
  article-title: Polysaccharide utilization loci of North Sea as basis for using SusC/D-protein expression for predicting major phytoplankton glycans
  publication-title: ISME J
  doi: 10.1038/s41396-018-0242-6
– volume: 78
  start-page: 892
  year: 2012
  end-page: 4
  ident: CR37
  article-title: Cultivated single-stranded DNA phages that infect marine prove difficult to detect with DNA-binding stains
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.06580-11
– volume: 86
  start-page: 8912
  year: 2012
  end-page: 3
  ident: CR41
  article-title: Complete genome sequence of bacteriophage P2559S
  publication-title: J Virol
  doi: 10.1128/JVI.01396-12
– ident: CR60
– volume: 82
  start-page: 1227
  year: 2016
  end-page: 36
  ident: CR87
  article-title: Alginate biosynthesis factories in : localization and correlation with alginate production level
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.03114-15
– volume: 53
  start-page: 157
  year: 1961
  end-page: 65
  ident: CR81
  article-title: The chemical composition of the diatom frustule
  publication-title: Proc Indian Acad Sci—Sect B
  doi: 10.1007/BF03051518
– volume: 5
  start-page: 265
  year: 2020
  end-page: 71
  ident: CR97
  article-title: Long-term stability and Red Queen-like strain dynamics in marine viruses
  publication-title: Nat Microbiol.
  doi: 10.1038/s41564-019-0628-x
– volume: 13
  start-page: 506
  year: 2021
  ident: CR73
  article-title: A roadmap for genome-based phage taxonomy
  publication-title: Viruses.
  doi: 10.3390/v13030506
– volume: 20
  start-page: 2880
  year: 2018
  end-page: 97
  ident: CR11
  article-title: Dynamics of transparent exopolymer particle production and aggregation during viral infection of the coccolithophore,
  publication-title: Environ Microbiol
  doi: 10.1111/1462-2920.14261
– volume: 64
  start-page: 2051
  year: 1998
  end-page: 60
  ident: CR34
  article-title: Occurrence of a sequence in marine cyanophages similar to that of T4 g20 and its application to PCR-based detection and quantification techniques
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.64.6.2051-2060.1998
– volume: 46
  start-page: W282
  year: 2018
  end-page: W8
  ident: CR64
  article-title: The Microbial Genomes Atlas (MiGA) webserver: taxonomic and gene diversity analysis of Archaea and Bacteria at the whole genome level
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gky467
– volume: 31
  start-page: 251
  year: 2008
  end-page: 7
  ident: CR67
  article-title: A standard operating procedure for phylogenetic inference (SOPPI) using (rRNA) marker genes
  publication-title: Syst Appl Microbiol
  doi: 10.1016/j.syapm.2008.08.003
– volume: 10
  start-page: 834
  year: 2012
  end-page: 48
  ident: CR82
  article-title: Cerium binding activity of pectins isolated from the seagrasses and
  publication-title: Mar Drugs
  doi: 10.3390/md10040834
– volume: 45
  start-page: 1320
  year: 2000
  end-page: 8
  ident: CR4
  article-title: Elements of a theory for the mechanisms controlling abundance, diversity, and biogeochemical role of lytic bacterial viruses in aquatic systems
  publication-title: Limnol Oceanogr
  doi: 10.4319/lo.2000.45.6.1320
– volume: 73
  start-page: 6730
  year: 2007
  end-page: 9
  ident: CR27
  article-title: Large variabilities in host strain susceptibility and phage host range govern interactions between lytic marine phages and their hosts
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.01399-07
– volume: 88
  start-page: 13111
  year: 2014
  end-page: 24
  ident: CR79
  article-title: Molecular characterization of a novel temperate bacteriophage, ФLM21, encoding DNA methyltransferase with CcrM-like specificity
  publication-title: J Virol
  doi: 10.1128/JVI.01875-14
– volume: 70
  start-page: 6753
  year: 2004
  end-page: 66
  ident: CR16
  article-title: Changes in bacterioplankton composition under different phytoplankton regimens
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.70.11.6753-6766.2004
– ident: CR89
– volume: 14
  start-page: 587
  year: 2017
  end-page: 9
  ident: CR59
  article-title: ModelFinder: fast model selection for accurate phylogenetic estimates
  publication-title: Nat Methods
  doi: 10.1038/nmeth.4285
– ident: CR10
– volume: 32
  start-page: 506
  year: 1996
  end-page: 16
  ident: CR33
  article-title: The effect of phosphate status on the kinetics of cyanophage infection in the oceanic cyanobacterium sp. WH78031
  publication-title: J Phycol
  doi: 10.1111/j.0022-3646.1996.00506.x
– volume: 5
  start-page: 506
  year: 2014
  ident: CR29
  article-title: Comparative genomics defines the core genome of the growing N4-like phage genus and identifies N4-like Roseophage specific genes
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2014.00506
– volume: 39
  start-page: 499
  year: 2020
  end-page: 509
  ident: CR63
  article-title: A genomic catalog of Earth’s microbiomes
  publication-title: Nat Biotechnol
  doi: 10.1038/s41587-020-0718-6
– volume: 14
  start-page: 1369
  year: 2020
  end-page: 83
  ident: CR85
  article-title: Polysaccharide niche partitioning of distinct clades during North Sea spring algal blooms
  publication-title: ISME J
  doi: 10.1038/s41396-020-0601-y
– volume: 177
  start-page: 1109
  year: 2019
  end-page: 23.e14
  ident: CR13
  article-title: Marine DNA viral macro- and microdiversity from pole to pole
  publication-title: Cell.
  doi: 10.1016/j.cell.2019.03.040
– volume: 28
  start-page: 237
  year: 1994
  end-page: 43
  ident: CR3
  article-title: The significance of viruses to mortality in aquatic microbial communities
  publication-title: Microb Ecol
  doi: 10.1007/BF00166813
– volume: 9
  start-page: 3301
  year: 2019
  ident: CR88
  article-title: Diversity and function of capsular polysaccharide in Acinetobacter baumannii
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2018.03301
– volume: 20
  start-page: 135
  year: 2007
  end-page: 9
  ident: CR6
  article-title: Exploring the vast diversity of marine viruses
  publication-title: Oceanography
  doi: 10.5670/oceanog.2007.58
– volume: 84
  start-page: e00061
  year: 2020
  end-page: 19
  ident: CR71
  article-title: Global organization and proposed megataxonomy of the virus world
  publication-title: Microbiol Mol Biol Rev
  doi: 10.1128/MMBR.00061-19
– volume: 18
  start-page: 275
  year: 1999
  end-page: 84
  ident: CR17
  article-title: Different community structure and temperature optima of heterotrophic picoplankton in various regions of the Southern Ocean
  publication-title: Aquat Microb Ecol
  doi: 10.3354/ame018275
– volume: 69
  start-page: 110
  year: 2019
  end-page: 23
  ident: CR72
  article-title: Analysis of Spounaviruses as a case study for the overdue reclassification of tailed phages
  publication-title: Syst Biol
  doi: 10.1093/sysbio/syz036
– volume: 35
  start-page: 518
  year: 2017
  end-page: 22
  ident: CR58
  article-title: UFBoot2: improving the ultrafast bootstrap approximation
  publication-title: Mol Biol Evolut
  doi: 10.1093/molbev/msx281
– volume: 343
  start-page: 60
  year: 1990
  end-page: 2
  ident: CR1
  article-title: Viral mortality of marine bacteria and cyanobacteria
  publication-title: Nature.
  doi: 10.1038/343060a0
– volume: 13
  start-page: 5993
  year: 2015
  end-page: 6018
  ident: CR20
  article-title: Diatom-specific oligosaccharide and polysaccharide structures help to unravel biosynthetic capabilities in diatoms
  publication-title: Mar Drugs
  doi: 10.3390/md13095993
– volume: 12
  start-page: 3035
  year: 2010
  end-page: 56
  ident: CR43
  article-title: Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-like myoviruses from diverse hosts and environments
  publication-title: Environ Microbiol
  doi: 10.1111/j.1462-2920.2010.02280.x
– volume: 64
  start-page: 535
  year: 1998
  end-page: 42
  ident: CR40
  article-title: Characterization of marine temperate phage-host systems isolated from Mamala Bay, Oahu, Hawaii
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.64.2.535-542.1998
– volume: 32
  start-page: 1363
  year: 2004
  end-page: 71
  ident: CR66
  article-title: ARB: a software environment for sequence data
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkh293
– volume: 109
  start-page: 2037
  year: 2012
  end-page: 42
  ident: CR31
  article-title: A novel lineage of myoviruses infecting cyanobacteria is widespread in the oceans
  publication-title: Proc Natl Acad Sci
  doi: 10.1073/pnas.1115467109
– volume: 10
  start-page: 82
  year: 2015
  ident: CR38
  article-title: Complete genome sequences of bacteriophages P12002L and P12002S, two lytic phages that infect a marine strain
  publication-title: Stand Genom Sci.
  doi: 10.1186/s40793-015-0076-z
– volume: 33
  start-page: 2379
  year: 2017
  end-page: 80
  ident: CR52
  article-title: ViPTree: the viral proteomic tree server
  publication-title: Bioinformatics.
  doi: 10.1093/bioinformatics/btx157
– volume: 5
  start-page: e11888
  year: 2016
  ident: CR19
  article-title: Recurring patterns in bacterioplankton dynamics during coastal spring algae blooms
  publication-title: eLife.
  doi: 10.7554/eLife.11888
– volume: 537
  start-page: 689
  year: 2016
  end-page: 93
  ident: CR14
  article-title: Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses
  publication-title: Nature.
  doi: 10.1038/nature19366
– volume: 6
  start-page: 637
  year: 2013
  end-page: 50
  ident: CR83
  article-title: Microbial alginate production, modification and its applications
  publication-title: Microb Biotechnol
  doi: 10.1111/1751-7915.12076
– volume: 11
  start-page: 1640
  year: 2017
  end-page: 50
  ident: CR24
  article-title: An alternative polysaccharide uptake mechanism of marine bacteria
  publication-title: ISME J
  doi: 10.1038/ismej.2017.26
– volume: 8
  year: 2017
  ident: CR50
  article-title: Single-virus genomics reveals hidden cosmopolitan and abundant viruses
  publication-title: Nat Commun
  doi: 10.1038/ncomms15892
– volume: 3
  start-page: 578
  year: 2013
  end-page: 86
  ident: CR77
  article-title: Networks of evolutionary interactions underlying the polyphyletic origin of ssDNA viruses
  publication-title: Curr Opin Virol
  doi: 10.1016/j.coviro.2013.06.010
– volume: 47
  start-page: D678
  year: 2019
  end-page: D86
  ident: CR48
  article-title: IMG/VR v.2.0: an integrated data management and analysis system for cultivated and environmental viral genomes
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gky1127
– volume: 21
  start-page: 1
  year: 2013
  end-page: 5
  ident: CR69
  article-title: Fake virus particles generated by fluorescence microscopy
  publication-title: Trends Microbiol
  doi: 10.1016/j.tim.2012.10.005
– volume: 92
  start-page: 99
  year: 1993
  end-page: 109
  ident: CR32
  article-title: Marine cyanophages infecting oceanic and coastal strains of : abundance, morphology, cross-infectivity and growth characteristics
  publication-title: Mar Ecol Prog Ser
  doi: 10.3354/meps092099
– volume: 8
  year: 2017
  ident: CR7
  article-title: Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans
  publication-title: Nat Commun
  doi: 10.1038/ncomms15955
– ident: CR75
– volume: 6
  start-page: 79
  year: 1992
  end-page: 90
  ident: CR2
  article-title: Estimation of virus production in the sea: II. field results
  publication-title: Mar Microb Food Webs
– volume: 2
  start-page: e00359
  year: 2017
  end-page: 16
  ident: CR47
  article-title: Environmental viral genomes shed new light on virus-host interactions in the ocean
  publication-title: mSphere.
  doi: 10.1128/mSphere.00359-16
– volume: 56
  start-page: 583
  year: 1990
  end-page: 9
  ident: CR26
  article-title: Size-selective grazing on bacteria by natural assemblages of estuarine flagellates and ciliates
  publication-title: Appl Environ Microbiol
  doi: 10.1128/aem.56.3.583-589.1990
– volume: 99
  start-page: 1331
  year: 2018
  end-page: 43
  ident: CR54
  article-title: Evaluation of the genomic diversity of viruses infecting bacteria, archaea and eukaryotes using a common bioinformatic platform: steps towards a unified taxonomy
  publication-title: J Gen Virol
  doi: 10.1099/jgv.0.001110
– volume: 347
  start-page: 467
  year: 1990
  end-page: 9
  ident: CR36
  article-title: Infection of phytoplankton by viruses and reduction of primary productivity
  publication-title: Nature
  doi: 10.1038/347467a0
– volume: 12
  start-page: 1268
  year: 2020
  ident: CR55
  article-title: VIRIDIC-A novel tool to calculate the intergenomic similarities of prokaryote-infecting viruses
  publication-title: Viruses.
  doi: 10.3390/v12111268
– volume: 101
  start-page: 3103
  year: 2017
  end-page: 19
  ident: CR90
  article-title: Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process
  publication-title: Appl Microbiol Biotechnol
  doi: 10.1007/s00253-017-8224-6
– volume: 32
  start-page: 268
  year: 2014
  end-page: 74
  ident: CR57
  article-title: IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies
  publication-title: Mol Biol Evolut
  doi: 10.1093/molbev/msu300
– volume: 9
  start-page: e1003987
  year: 2013
  ident: CR46
  article-title: Expanding the marine virosphere using metagenomics
  publication-title: PLOS Genet
  doi: 10.1371/journal.pgen.1003987
– volume: 336
  start-page: 608
  year: 2012
  end-page: 11
  ident: CR18
  article-title: Substrate-controlled succession of marine bacterioplankton populations induced by a phytoplankton bloom
  publication-title: Science.
  doi: 10.1126/science.1218344
– volume: 46
  start-page: W246
  year: 2018
  end-page: W51
  ident: CR68
  article-title: CRISPRCasFinder, an update of CRISRFinder, includes a portable version, enhanced performance and integrates search for Cas proteins
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gky425
– volume: 17
  start-page: 3500
  year: 2015
  end-page: 14
  ident: CR92
  article-title: Comparison of bacterial communities on limnic versus coastal marine particles reveals profound differences in colonization
  publication-title: Environ Microbiol
  doi: 10.1111/1462-2920.12466
– volume: 22
  start-page: 1540
  year: 2006
  end-page: 2
  ident: CR100
  article-title: Pvclust: an R package for assessing the uncertainty in hierarchical clustering
  publication-title: Bioinformatics.
  doi: 10.1093/bioinformatics/btl117
– volume: 13
  start-page: 823
  year: 2011
  ident: CR80
  article-title: The importance of chitin in the marine environment
  publication-title: Mar Biotechnol
  doi: 10.1007/s10126-011-9388-1
– volume: 13
  start-page: 2800
  year: 2019
  end-page: 16
  ident: CR84
  article-title: In marine the bulk of glycan degradation during algae blooms is mediated by few clades using a restricted set of genes
  publication-title: ISME J
  doi: 10.1038/s41396-019-0476-y
– volume: 86
  start-page: 8907
  year: 2012
  end-page: 8
  ident: CR42
  article-title: Complete genome sequences of two bacteriophages, P12024S and P12024L
  publication-title: J Virol
  doi: 10.1128/JVI.01327-12
– ident: CR95
– volume: 491
  start-page: 413
  year: 2012
  end-page: 7
  ident: CR76
  article-title: The Mu transpososome structure sheds light on DDE recombinase evolution
  publication-title: Nature.
  doi: 10.1038/nature11602
– volume: 7
  start-page: e00805
  year: 2016
  end-page: 16
  ident: CR45
  article-title: Genomes of abundant and widespread viruses from the deep ocean
  publication-title: mBio.
  doi: 10.1128/mBio.00805-16
– volume: 33
  start-page: 3396
  year: 2017
  end-page: 404
  ident: CR53
  article-title: VICTOR: genome-based phylogeny and classification of prokaryotic viruses
  publication-title: Bioinformatics.
  doi: 10.1093/bioinformatics/btx440
– volume: 33
  start-page: 3113
  year: 2017
  end-page: 4
  ident: CR62
  article-title: WIsH: who is the host? Predicting prokaryotic hosts from metagenomic phage contigs
  publication-title: Bioinformatics.
  doi: 10.1093/bioinformatics/btx383
– volume: 10
  year: 2009
  ident: CR61
  article-title: BLAST+: architecture and applications
  publication-title: BMC Bioinform
  doi: 10.1186/1471-2105-10-421
– volume: 5
  start-page: e15388
  year: 2010
  ident: CR78
  article-title: Structural relationships in the lysozyme superfamily: significant evidence for glycoside hydrolase signature motifs
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0015388
– volume: 12
  start-page: 2894
  year: 2018
  end-page: 906
  ident: CR23
  article-title: Adaptive mechanisms that provide competitive advantages to marine during microalgal blooms
  publication-title: ISME J
  doi: 10.1038/s41396-018-0243-5
– volume: 32
  start-page: 1792
  year: 2004
  end-page: 7
  ident: CR56
  article-title: MUSCLE: multiple sequence alignment with high accuracy and high throughput
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gkh340
– volume: 343
  start-page: 60
  year: 1990
  end-page: 2
  ident: CR35
  article-title: Viral mortality of marine bacteria and cyanobacteria
  publication-title: Nature.
  doi: 10.1038/343060a0
– volume: 50
  start-page: 1043
  year: 1963
  end-page: 51
  ident: CR74
  article-title: Bacteriophage-induced mutation in
  publication-title: Proc Natl Acad Sci USA.
  doi: 10.1073/pnas.50.6.1043
– volume: 100
  start-page: 2141
  year: 2016
  end-page: 51
  ident: CR91
  article-title: Bacteriophage-encoded depolymerases: their diversity and biotechnological applications
  publication-title: Appl Microbiol Biotechnol
  doi: 10.1007/s00253-015-7247-0
– volume: 64
  start-page: 4128
  year: 1998
  end-page: 33
  ident: CR30
  article-title: Bacteriophage diversity in the North Sea
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.64.11.4128-4133.1998
– volume: 58
  start-page: 230
  year: 2004
  end-page: 42
  ident: CR15
  article-title: 40-year long-term study of microbial parameters near Helgoland (German Bight, North Sea): historical view and future perspectives
  publication-title: Helgol Mar Res
  doi: 10.1007/s10152-004-0189-z
– volume: 13
  start-page: 1404
  year: 2019
  end-page: 21
  ident: CR28
  article-title: Cobaviruses – a new globally distributed phage group infecting in marine ecosystems
  publication-title: ISME J
  doi: 10.1038/s41396-019-0362-7
– volume: 30
  start-page: 1312
  year: 2014
  end-page: 3
  ident: CR65
  article-title: RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies
  publication-title: Bioinformatics.
  doi: 10.1093/bioinformatics/btu033
– volume: 9
  start-page: e1003987
  year: 2013
  ident: 2024011018032905700_CR46
  article-title: Expanding the marine virosphere using metagenomics
  publication-title: PLOS Genet
  doi: 10.1371/journal.pgen.1003987
– volume: 99
  start-page: 1331
  year: 2018
  ident: 2024011018032905700_CR54
  article-title: Evaluation of the genomic diversity of viruses infecting bacteria, archaea and eukaryotes using a common bioinformatic platform: steps towards a unified taxonomy
  publication-title: J Gen Virol
  doi: 10.1099/jgv.0.001110
– volume: 12
  start-page: 1268
  year: 2020
  ident: 2024011018032905700_CR55
  article-title: VIRIDIC-A novel tool to calculate the intergenomic similarities of prokaryote-infecting viruses
  publication-title: Viruses.
  doi: 10.3390/v12111268
– volume: 38
  start-page: 66
  year: 2017
  ident: 2024011018032905700_CR8
  article-title: Embracing the enemy: the diversification of microbial gene repertoires by phage-mediated horizontal gene transfer
  publication-title: Curr Opin Microbiol.
  doi: 10.1016/j.mib.2017.04.010
– volume: 78
  start-page: 892
  year: 2012
  ident: 2024011018032905700_CR37
  article-title: Cultivated single-stranded DNA phages that infect marine Bacteroidetes prove difficult to detect with DNA-binding stains
  publication-title: Appl Environ Microbiol.
  doi: 10.1128/AEM.06580-11
– volume: 2
  start-page: e00359
  year: 2017
  ident: 2024011018032905700_CR47
  article-title: Environmental viral genomes shed new light on virus-host interactions in the ocean
  publication-title: mSphere
  doi: 10.1128/mSphere.00359-16
– volume: 109
  start-page: 2037
  year: 2012
  ident: 2024011018032905700_CR31
  article-title: A novel lineage of myoviruses infecting cyanobacteria is widespread in the oceans
  publication-title: Proc Natl Acad Sci.
  doi: 10.1073/pnas.1115467109
– volume: 34
  start-page: 217
  year: 1976
  ident: 2024011018032905700_CR21
  article-title: Polysaccharides of marine diatoms with special reference to Chaetoceros species
  publication-title: Mar Biol.
  doi: 10.1007/BF00388798
– volume: 46
  start-page: W282
  year: 2018
  ident: 2024011018032905700_CR64
  article-title: The Microbial Genomes Atlas (MiGA) webserver: taxonomic and gene diversity analysis of Archaea and Bacteria at the whole genome level
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gky467
– volume: 86
  start-page: 8907
  year: 2012
  ident: 2024011018032905700_CR42
  article-title: Complete genome sequences of two Persicivirga bacteriophages, P12024S and P12024L
  publication-title: J Virol
  doi: 10.1128/JVI.01327-12
– volume: 491
  start-page: 413
  year: 2012
  ident: 2024011018032905700_CR76
  article-title: The Mu transpososome structure sheds light on DDE recombinase evolution
  publication-title: Nature
  doi: 10.1038/nature11602
– volume: 45
  start-page: 1320
  year: 2000
  ident: 2024011018032905700_CR4
  article-title: Elements of a theory for the mechanisms controlling abundance, diversity, and biogeochemical role of lytic bacterial viruses in aquatic systems
  publication-title: Limnol Oceanogr.
  doi: 10.4319/lo.2000.45.6.1320
– volume: 12
  start-page: 3035
  year: 2010
  ident: 2024011018032905700_CR43
  article-title: Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-like myoviruses from diverse hosts and environments
  publication-title: Environ Microbiol.
  doi: 10.1111/j.1462-2920.2010.02280.x
– volume: 13
  start-page: 76
  year: 2019
  ident: 2024011018032905700_CR86
  article-title: Polysaccharide utilization loci of North Sea Flavobacteriia as basis for using SusC/D-protein expression for predicting major phytoplankton glycans
  publication-title: ISME J
  doi: 10.1038/s41396-018-0242-6
– volume: 28
  start-page: 237
  year: 1994
  ident: 2024011018032905700_CR3
  article-title: The significance of viruses to mortality in aquatic microbial communities
  publication-title: Microb Ecol.
  doi: 10.1007/BF00166813
– volume: 6
  start-page: 79
  year: 1992
  ident: 2024011018032905700_CR2
  article-title: Estimation of virus production in the sea: II. field results
  publication-title: Mar Microb Food Webs
– volume: 5
  start-page: 506
  year: 2014
  ident: 2024011018032905700_CR29
  article-title: Comparative genomics defines the core genome of the growing N4-like phage genus and identifies N4-like Roseophage specific genes
  publication-title: Front Microbiol.
  doi: 10.3389/fmicb.2014.00506
– volume: 8
  start-page: 15955
  year: 2017
  ident: 2024011018032905700_CR7
  article-title: Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans
  publication-title: Nat Commun.
  doi: 10.1038/ncomms15955
– volume: 20
  start-page: 2880
  year: 2018
  ident: 2024011018032905700_CR11
  article-title: Dynamics of transparent exopolymer particle production and aggregation during viral infection of the coccolithophore, Emiliania huxleyi
  publication-title: Environ Microbiol.
  doi: 10.1111/1462-2920.14261
– volume: 5
  start-page: e15388
  year: 2010
  ident: 2024011018032905700_CR78
  article-title: Structural relationships in the lysozyme superfamily: significant evidence for glycoside hydrolase signature motifs
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0015388
– volume: 13
  start-page: 5993
  year: 2015
  ident: 2024011018032905700_CR20
  article-title: Diatom-specific oligosaccharide and polysaccharide structures help to unravel biosynthetic capabilities in diatoms
  publication-title: Mar Drugs
  doi: 10.3390/md13095993
– volume: 13
  start-page: 506
  year: 2021
  ident: 2024011018032905700_CR73
  article-title: A roadmap for genome-based phage taxonomy
  publication-title: Viruses.
  doi: 10.3390/v13030506
– volume: 347
  start-page: 467
  year: 1990
  ident: 2024011018032905700_CR36
  article-title: Infection of phytoplankton by viruses and reduction of primary productivity
  publication-title: Nature
  doi: 10.1038/347467a0
– volume: 86
  start-page: 8912
  year: 2012
  ident: 2024011018032905700_CR41
  article-title: Complete genome sequence of Croceibacter bacteriophage P2559S
  publication-title: J Virol
  doi: 10.1128/JVI.01396-12
– volume: 33
  start-page: 3396
  year: 2017
  ident: 2024011018032905700_CR53
  article-title: VICTOR: genome-based phylogeny and classification of prokaryotic viruses
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btx440
– volume: 32
  start-page: 506
  year: 1996
  ident: 2024011018032905700_CR33
  article-title: The effect of phosphate status on the kinetics of cyanophage infection in the oceanic cyanobacterium Synechococcus sp. WH78031
  publication-title: J Phycol.
  doi: 10.1111/j.0022-3646.1996.00506.x
– volume: 46
  start-page: W246
  year: 2018
  ident: 2024011018032905700_CR68
  article-title: CRISPRCasFinder, an update of CRISRFinder, includes a portable version, enhanced performance and integrates search for Cas proteins
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gky425
– start-page: 91
  volume-title: Bacteriophages: methods and protocols, Volume 2 Molecular and Applied Aspects
  year: 2009
  ident: 2024011018032905700_CR75
  doi: 10.1007/978-1-60327-565-1_7
– ident: 2024011018032905700_CR89
– volume: 100
  start-page: 2141
  year: 2016
  ident: 2024011018032905700_CR91
  article-title: Bacteriophage-encoded depolymerases: their diversity and biotechnological applications
  publication-title: Appl Microbiol Biotechnol.
  doi: 10.1007/s00253-015-7247-0
– volume: 7
  start-page: 1274
  year: 2013
  ident: 2024011018032905700_CR96
  article-title: Short-term observations of marine bacterial and viral communities: patterns, connections and resilience
  publication-title: ISME J
  doi: 10.1038/ismej.2013.19
– volume: 9
  start-page: 2386
  year: 2015
  ident: 2024011018032905700_CR49
  article-title: Single-cell genomics-based analysis of virus–host interactions in marine surface bacterioplankton
  publication-title: ISME J
  doi: 10.1038/ismej.2015.48
– volume: 70
  start-page: 6753
  year: 2004
  ident: 2024011018032905700_CR16
  article-title: Changes in bacterioplankton composition under different phytoplankton regimens
  publication-title: Appl Environ Microbiol.
  doi: 10.1128/AEM.70.11.6753-6766.2004
– volume: 7
  start-page: 377
  year: 2003
  ident: 2024011018032905700_CR39
  article-title: Isolation and characterization of marine psychrophilic phage-host systems from Arctic sea ice
  publication-title: Extremophiles.
  doi: 10.1007/s00792-003-0334-7
– volume: 21
  start-page: 1
  year: 2013
  ident: 2024011018032905700_CR69
  article-title: Fake virus particles generated by fluorescence microscopy
  publication-title: Trends Microbiol.
  doi: 10.1016/j.tim.2012.10.005
– volume: 6
  start-page: 637
  year: 2013
  ident: 2024011018032905700_CR83
  article-title: Microbial alginate production, modification and its applications
  publication-title: Microb Biotechnol.
  doi: 10.1111/1751-7915.12076
– volume: 20
  start-page: 135
  year: 2007
  ident: 2024011018032905700_CR6
  article-title: Exploring the vast diversity of marine viruses
  publication-title: Oceanography
  doi: 10.5670/oceanog.2007.58
– volume: 101
  start-page: 3103
  year: 2017
  ident: 2024011018032905700_CR90
  article-title: Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process
  publication-title: Appl Microbiol Biotechnol.
  doi: 10.1007/s00253-017-8224-6
– volume: 2021.06.14.448304
  year: 2021
  ident: 2024011018032905700_CR51
  article-title: VirClust, a tool for hierarchical clustering, core gene detection and annotation of (prokaryotic) viruses
  publication-title: bioRxiv.
– volume: 531
  start-page: 466
  year: 2016
  ident: 2024011018032905700_CR9
  article-title: Lytic to temperate switching of viral communities
  publication-title: Nature
  doi: 10.1038/nature17193
– volume: 46
  start-page: 235
  year: 2008
  ident: 2024011018032905700_CR70
  article-title: Dinoflagellates, diatoms, and their viruses
  publication-title: J Microbiol.
  doi: 10.1007/s12275-008-0098-y
– volume: 84
  start-page: e00061
  year: 2020
  ident: 2024011018032905700_CR71
  article-title: Global organization and proposed megataxonomy of the virus world
  publication-title: Microbiol Mol Biol Rev.
  doi: 10.1128/MMBR.00061-19
– start-page: 677
  volume-title: The Prokaryotes: Volume 7: Proteobacteria: Delta, Epsilon Subclass
  year: 2006
  ident: 2024011018032905700_CR95
– volume: 176
  start-page: 268
  year: 2019
  ident: 2024011018032905700_CR94
  article-title: A host-produced quorum-sensing autoinducer controls a phage lysis-lysogeny decision
  publication-title: Cell
  doi: 10.1016/j.cell.2018.10.059
– volume: 88
  start-page: 13111
  year: 2014
  ident: 2024011018032905700_CR79
  article-title: Molecular characterization of a novel temperate Sinorhizobium bacteriophage, ФLM21, encoding DNA methyltransferase with CcrM-like specificity
  publication-title: J Virol
  doi: 10.1128/JVI.01875-14
– volume: 343
  start-page: 60
  year: 1990
  ident: 2024011018032905700_CR35
  article-title: Viral mortality of marine bacteria and cyanobacteria
  publication-title: Nature
  doi: 10.1038/343060a0
– volume: 92
  start-page: 99
  year: 1993
  ident: 2024011018032905700_CR32
  article-title: Marine cyanophages infecting oceanic and coastal strains of Synechococcus: abundance, morphology, cross-infectivity and growth characteristics
  publication-title: Mar Ecol Prog Ser.
  doi: 10.3354/meps092099
– volume: 336
  start-page: 608
  year: 2012
  ident: 2024011018032905700_CR18
  article-title: Substrate-controlled succession of marine bacterioplankton populations induced by a phytoplankton bloom
  publication-title: Science
  doi: 10.1126/science.1218344
– volume: 56
  start-page: 583
  year: 1990
  ident: 2024011018032905700_CR26
  article-title: Size-selective grazing on bacteria by natural assemblages of estuarine flagellates and ciliates
  publication-title: Appl Environ Microbiol.
  doi: 10.1128/aem.56.3.583-589.1990
– volume: 14
  start-page: 587
  year: 2017
  ident: 2024011018032905700_CR59
  article-title: ModelFinder: fast model selection for accurate phylogenetic estimates
  publication-title: Nat Methods
  doi: 10.1038/nmeth.4285
– volume: 11
  start-page: 1640
  year: 2017
  ident: 2024011018032905700_CR24
  article-title: An alternative polysaccharide uptake mechanism of marine bacteria
  publication-title: ISME J
  doi: 10.1038/ismej.2017.26
– volume: 17
  start-page: 3500
  year: 2015
  ident: 2024011018032905700_CR92
  article-title: Comparison of bacterial communities on limnic versus coastal marine particles reveals profound differences in colonization
  publication-title: Environ Microbiol.
  doi: 10.1111/1462-2920.12466
– volume: 14
  start-page: 1369
  year: 2020
  ident: 2024011018032905700_CR85
  article-title: Polysaccharide niche partitioning of distinct Polaribacter clades during North Sea spring algal blooms
  publication-title: ISME J
  doi: 10.1038/s41396-020-0601-y
– volume: 10
  start-page: e00638
  year: 2019
  ident: 2024011018032905700_CR93
  article-title: Phage-encoded LuxR-type receptors responsive to host-produced bacterial quorum-sensing autoinducers
  publication-title: mBio.
  doi: 10.1128/mBio.00638-19
– volume: 13
  start-page: 1404
  year: 2019
  ident: 2024011018032905700_CR28
  article-title: Cobaviruses – a new globally distributed phage group infecting Rhodobacteraceae in marine ecosystems
  publication-title: ISME J
  doi: 10.1038/s41396-019-0362-7
– volume: 343
  start-page: 60
  year: 1990
  ident: 2024011018032905700_CR1
  article-title: Viral mortality of marine bacteria and cyanobacteria
  publication-title: Nature
  doi: 10.1038/343060a0
– volume: 5
  start-page: e11888
  year: 2016
  ident: 2024011018032905700_CR19
  article-title: Recurring patterns in bacterioplankton dynamics during coastal spring algae blooms
  publication-title: eLife
  doi: 10.7554/eLife.11888
– volume: 10
  start-page: 834
  year: 2012
  ident: 2024011018032905700_CR82
  article-title: Cerium binding activity of pectins isolated from the seagrasses Zostera marina and Phyllospadix iwatensis
  publication-title: Mar Drugs
  doi: 10.3390/md10040834
– ident: 2024011018032905700_CR25
– volume: 177
  start-page: 1109
  year: 2019
  ident: 2024011018032905700_CR13
  article-title: Marine DNA viral macro- and microdiversity from pole to pole
  publication-title: Cell
  doi: 10.1016/j.cell.2019.03.040
– volume: 64
  start-page: 535
  year: 1998
  ident: 2024011018032905700_CR40
  article-title: Characterization of marine temperate phage-host systems isolated from Mamala Bay, Oahu, Hawaii
  publication-title: Appl Environ Microbiol.
  doi: 10.1128/AEM.64.2.535-542.1998
– volume: 10
  start-page: 421
  year: 2009
  ident: 2024011018032905700_CR61
  article-title: BLAST+: architecture and applications
  publication-title: BMC Bioinform
  doi: 10.1186/1471-2105-10-421
– volume: 13
  start-page: 2800
  year: 2019
  ident: 2024011018032905700_CR84
  article-title: In marine Bacteroidetes the bulk of glycan degradation during algae blooms is mediated by few clades using a restricted set of genes
  publication-title: ISME J
  doi: 10.1038/s41396-019-0476-y
– volume: 30
  start-page: 1312
  year: 2014
  ident: 2024011018032905700_CR65
  article-title: RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btu033
– ident: 2024011018032905700_CR10
– volume: 340
  start-page: 467
  year: 1989
  ident: 2024011018032905700_CR12
  article-title: High abundance of viruses found in aquatic environments
  publication-title: Nature
  doi: 10.1038/340467a0
– volume: 9
  start-page: 3301
  year: 2019
  ident: 2024011018032905700_CR88
  article-title: Diversity and function of capsular polysaccharide in Acinetobacter baumannii
  publication-title: Front Microbiol.
  doi: 10.3389/fmicb.2018.03301
– volume: 64
  start-page: 2051
  year: 1998
  ident: 2024011018032905700_CR34
  article-title: Occurrence of a sequence in marine cyanophages similar to that of T4 g20 and its application to PCR-based detection and quantification techniques
  publication-title: Appl Environ Microbiol.
  doi: 10.1128/AEM.64.6.2051-2060.1998
– volume: 32
  start-page: 268
  year: 2014
  ident: 2024011018032905700_CR57
  article-title: IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies
  publication-title: Mol Biol Evolut
  doi: 10.1093/molbev/msu300
– volume: 73
  start-page: 6730
  year: 2007
  ident: 2024011018032905700_CR27
  article-title: Large variabilities in host strain susceptibility and phage host range govern interactions between lytic marine phages and their Flavobacterium hosts
  publication-title: Appl Environ Microbiol.
  doi: 10.1128/AEM.01399-07
– volume: 537
  start-page: 689
  year: 2016
  ident: 2024011018032905700_CR14
  article-title: Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses
  publication-title: Nature
  doi: 10.1038/nature19366
– volume: 32
  start-page: 1363
  year: 2004
  ident: 2024011018032905700_CR66
  article-title: ARB: a software environment for sequence data
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkh293
– volume: 69
  start-page: 110
  year: 2019
  ident: 2024011018032905700_CR72
  article-title: Analysis of Spounaviruses as a case study for the overdue reclassification of tailed phages
  publication-title: Syst Biol.
  doi: 10.1093/sysbio/syz036
– volume: 3
  start-page: 578
  year: 2013
  ident: 2024011018032905700_CR77
  article-title: Networks of evolutionary interactions underlying the polyphyletic origin of ssDNA viruses
  publication-title: Curr Opin Virol
  doi: 10.1016/j.coviro.2013.06.010
– volume: 32
  start-page: 1792
  year: 2004
  ident: 2024011018032905700_CR56
  article-title: MUSCLE: multiple sequence alignment with high accuracy and high throughput
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkh340
– volume: 33
  start-page: 295
  year: 2010
  ident: 2024011018032905700_CR98
  article-title: Helgoland Roads, North Sea: 45 years of change
  publication-title: Estuaries Coasts
  doi: 10.1007/s12237-009-9228-y
– volume: 7
  start-page: e00805
  year: 2016
  ident: 2024011018032905700_CR45
  article-title: Genomes of abundant and widespread viruses from the deep ocean
  publication-title: mBio.
  doi: 10.1128/mBio.00805-16
– volume: 82
  start-page: 1227
  year: 2016
  ident: 2024011018032905700_CR87
  article-title: Alginate biosynthesis factories in Pseudomonas fluorescens: localization and correlation with alginate production level
  publication-title: Appl Environ Microbiol.
  doi: 10.1128/AEM.03114-15
– volume: 31
  start-page: 251
  year: 2008
  ident: 2024011018032905700_CR67
  article-title: A standard operating procedure for phylogenetic inference (SOPPI) using (rRNA) marker genes
  publication-title: Syst Appl Microbiol.
  doi: 10.1016/j.syapm.2008.08.003
– volume: 13
  start-page: 823
  year: 2011
  ident: 2024011018032905700_CR80
  article-title: The importance of chitin in the marine environment
  publication-title: Mar Biotechnol.
  doi: 10.1007/s10126-011-9388-1
– volume: 22
  start-page: 1540
  year: 2006
  ident: 2024011018032905700_CR100
  article-title: Pvclust: an R package for assessing the uncertainty in hierarchical clustering
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btl117
– volume: 33
  start-page: 3113
  year: 2017
  ident: 2024011018032905700_CR62
  article-title: WIsH: who is the host? Predicting prokaryotic hosts from metagenomic phage contigs
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btx383
– volume: 64
  start-page: 4128
  year: 1998
  ident: 2024011018032905700_CR30
  article-title: Bacteriophage diversity in the North Sea
  publication-title: Appl Environ Microbiol.
  doi: 10.1128/AEM.64.11.4128-4133.1998
– volume: 53
  start-page: 157
  year: 1961
  ident: 2024011018032905700_CR81
  article-title: The chemical composition of the diatom frustule
  publication-title: Proc Indian Acad Sci—Sect B
  doi: 10.1007/BF03051518
– start-page: 195
  volume-title: The polysaccharides
  year: 1983
  ident: 2024011018032905700_CR22
  doi: 10.1016/B978-0-12-065602-8.50009-1
– volume: 18
  start-page: 275
  year: 1999
  ident: 2024011018032905700_CR17
  article-title: Different community structure and temperature optima of heterotrophic picoplankton in various regions of the Southern Ocean
  publication-title: Aquat Microb Ecol.
  doi: 10.3354/ame018275
– volume: 19
  start-page: 455
  year: 2012
  ident: 2024011018032905700_CR44
  article-title: SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing
  publication-title: J Comput Biol.
  doi: 10.1089/cmb.2012.0021
– volume: 5
  start-page: 265
  year: 2020
  ident: 2024011018032905700_CR97
  article-title: Long-term stability and Red Queen-like strain dynamics in marine viruses
  publication-title: Nat Microbiol.
  doi: 10.1038/s41564-019-0628-x
– volume: 49
  start-page: 781
  year: 1999
  ident: 2024011018032905700_CR5
  article-title: Viruses and nutrient cycles in the sea: viruses play critical roles in the structure and function of aquatic food webs
  publication-title: BioScience
  doi: 10.2307/1313569
– volume: 50
  start-page: 1043
  year: 1963
  ident: 2024011018032905700_CR74
  article-title: Bacteriophage-induced mutation in Escherichia coli
  publication-title: Proc Natl Acad Sci USA.
  doi: 10.1073/pnas.50.6.1043
– volume: 7
  start-page: 174
  year: 2019
  ident: 2024011018032905700_CR99
  article-title: Selective inference for testing trees and edges in phylogenetics
  publication-title: Front Ecol Evolut
  doi: 10.3389/fevo.2019.00174
– volume: 33
  start-page: 2379
  year: 2017
  ident: 2024011018032905700_CR52
  article-title: ViPTree: the viral proteomic tree server
  publication-title: Bioinformatics
  doi: 10.1093/bioinformatics/btx157
– volume: 10
  start-page: 82
  year: 2015
  ident: 2024011018032905700_CR38
  article-title: Complete genome sequences of bacteriophages P12002L and P12002S, two lytic phages that infect a marine Polaribacter strain
  publication-title: Stand Genom Sci.
  doi: 10.1186/s40793-015-0076-z
– volume: 12
  start-page: 2894
  year: 2018
  ident: 2024011018032905700_CR23
  article-title: Adaptive mechanisms that provide competitive advantages to marine Bacteroidetes during microalgal blooms
  publication-title: ISME J
  doi: 10.1038/s41396-018-0243-5
– volume: 58
  start-page: 230
  year: 2004
  ident: 2024011018032905700_CR15
  article-title: 40-year long-term study of microbial parameters near Helgoland (German Bight, North Sea): historical view and future perspectives
  publication-title: Helgol Mar Res.
  doi: 10.1007/s10152-004-0189-z
– volume: 39
  start-page: 499
  year: 2020
  ident: 2024011018032905700_CR63
  article-title: A genomic catalog of Earth’s microbiomes
  publication-title: Nat Biotechnol.
  doi: 10.1038/s41587-020-0718-6
– volume: 8
  start-page: 15892
  year: 2017
  ident: 2024011018032905700_CR50
  article-title: Single-virus genomics reveals hidden cosmopolitan and abundant viruses
  publication-title: Nat Commun.
  doi: 10.1038/ncomms15892
– ident: 2024011018032905700_CR60
– volume: 47
  start-page: D678
  year: 2019
  ident: 2024011018032905700_CR48
  article-title: IMG/VR v.2.0: an integrated data management and analysis system for cultivated and environmental viral genomes
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gky1127
– volume: 35
  start-page: 518
  year: 2017
  ident: 2024011018032905700_CR58
  article-title: UFBoot2: improving the ultrafast bootstrap approximation
  publication-title: Mol Biol Evolut
  doi: 10.1093/molbev/msx281
SSID ssj0057667
Score 2.5311525
Snippet It is generally recognized that phages are a mortality factor for their bacterial hosts. This could be particularly true in spring phytoplankton blooms, which...
SourceID pubmedcentral
proquest
pubmed
crossref
springer
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 555
SubjectTerms 45/22
45/23
631/326/1321
631/326/171/1878
Bacteria
Bacteriophages - genetics
Biodegradation
Biomedical and Life Sciences
CRISPR
Ecology
Eutrophication
Evolutionary Biology
Flavobacteriaceae - genetics
Genera
Genomic analysis
Heterotrophic bacteria
Humans
Life Sciences
Metagenome
Microbial Ecology
Microbial Genetics and Genomics
Microbiology
Microorganisms
New families
New species
North Sea
Phages
Phytoplankton
Plankton
Polysaccharides
Saccharides
Title Highly diverse flavobacterial phages isolated from North Sea spring blooms
URI https://link.springer.com/article/10.1038/s41396-021-01097-4
https://www.ncbi.nlm.nih.gov/pubmed/34475519
https://www.proquest.com/docview/2621425785
https://www.proquest.com/docview/2569382984
https://pubmed.ncbi.nlm.nih.gov/PMC8776804
Volume 16
WOSCitedRecordID wos000692061100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVASL
  databaseName: Oxford Journals Open Access Collection
  customDbUrl:
  eissn: 1751-7370
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0057667
  issn: 1751-7362
  databaseCode: TOX
  dateStart: 20070101
  isFulltext: true
  titleUrlDefault: https://academic.oup.com/journals/
  providerName: Oxford University Press
– providerCode: PRVPQU
  databaseName: Biological Science Database
  customDbUrl:
  eissn: 1751-7370
  dateEnd: 20241207
  omitProxy: false
  ssIdentifier: ssj0057667
  issn: 1751-7362
  databaseCode: M7P
  dateStart: 20070501
  isFulltext: true
  titleUrlDefault: http://search.proquest.com/biologicalscijournals
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Environmental Science Database (subscripiton)
  customDbUrl:
  eissn: 1751-7370
  dateEnd: 20241207
  omitProxy: false
  ssIdentifier: ssj0057667
  issn: 1751-7362
  databaseCode: PATMY
  dateStart: 20070501
  isFulltext: true
  titleUrlDefault: http://search.proquest.com/environmentalscience
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Central
  customDbUrl:
  eissn: 1751-7370
  dateEnd: 20241207
  omitProxy: false
  ssIdentifier: ssj0057667
  issn: 1751-7362
  databaseCode: BENPR
  dateStart: 20070501
  isFulltext: true
  titleUrlDefault: https://www.proquest.com/central
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Proquest Health and Medical Complete
  customDbUrl:
  eissn: 1751-7370
  dateEnd: 20241207
  omitProxy: false
  ssIdentifier: ssj0057667
  issn: 1751-7362
  databaseCode: 7X7
  dateStart: 20070501
  isFulltext: true
  titleUrlDefault: https://search.proquest.com/healthcomplete
  providerName: ProQuest
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT9wwEB7xaCUulD6gS2FlpN5aiyTexPapahEI9bBdFSrtLXJsR6y0ZBeyIPHvO-Mki7aoXLhEkfyInbHn4Rl_A_BZoBBLhLbcqcTygfaWF4SM6FLjUMINUES7kGxCDodqPNaj9sCtbsMqO54YGLWbWTojP04yAgcjaJZv8xtOWaPIu9qm0FiHTUJJECF0b9RxYlSlQwZZlJAxl8ip20szkVDHNTLvEH5LxnSkJR-sCqYn2ubToMl_PKdBIJ29eelUdmC7VUXZ92btvIU1X72D101yyof38JNCQKYPzIXIDc_KqbnHzR_AnbHZ_Ao5Uc0muHZRXXWM7qmw4AViF96wZtSM4uKv6w_w5-z08uSct5kXuEUNbsFNYiMtKNmU0doXhRrEsUcjOkM7HLmnKQkyJitFbLQr4wLfoxLpitKuiFJntdiFjWpW-Y_AsBdbqDSKvUXtsSyMSqUopc2UkRq1nx7E3W_PbQtLTtkxpnlwjwuVN6TKkVR5IFWObb4s28wbUI5nax90ZMjbDVrnjzTowdGyGLcW-UtM5Wd3WCfNtFCJpkHuNcRffi4AJaL22wO5siyWFQi2e7WkmlwF-G4l0cSLsM-v3QJ6HNb_Z7H__Cw-wVZCFzNCPPkBbCxu7_whvLL3i0l924d1OZbhqfqw-eN0OPrdD1sFn5e_xn8Bls8Whw
linkProvider ProQuest
linkToHtml http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB5VBQQX3tCFAkaCE1jNYxPbB4QQULW0rJAo0t5cx3bUlZbsttkW7Z_iNzLjPKqlorceuEWKndjx-JuZzPgbgFcpKrEkVZY7mVg-VN7ygpgRXWYcarghqmgXik2I0UiOx-rbGvzuzsJQWmWHiQGo3czSP_KtJCdyMKJmeT8_5lQ1iqKrXQmNRiz2_PIXumz1u91PuL6vk2T788HHHd5WFeAWrZMFN4lFL54KKRmlfFHIYRx7dBBz9DERGUxJdCh5mcZGuTIu8DoqccyI5EWUOUvkSwj51xDHBaWQiXHv4KHpHirWokaOuUDN0B7SiVK5VaOyCOm-5LxHSvDhqiK8YN1eTNL8K1IbFOD2nf_t092F262pzT40e-MerPnqPtxoim8uH8AXSnGZLpkLmSmelVNzhuAWyKux2_wIkbZmE9ybaI47RudwWIhyse_esOYrMcr7_1k_hB9XMpFHsF7NKr8BDJ9iC5lFsbdoHZeFkZlIS2FzaYRC624AcbfM2ra061T9Y6pD-D-VuhENjaKhg2ho7POm7zNvSEcubb3ZLbtuAajW52s-gJf9bYQOigeZys9OsU2Wq1Qmigb5uBG2_nWBCBKt-wGIFTHsGxAt-eqdanIU6MmlQBc2wme-7QT2fFj_nsWTy2fxAm7uHHzd1_u7o72ncCuhQyghd34T1hcnp_4ZXLdni0l98jxsSQaHVy3IfwDPMm4N
linkToPdf http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB5V5SEuvB8LBYwEJ7A2b9sHhBBlRSmsVgKk3oxjO-pKS3ZptkX71_h1zDjJVktFbz1wixQ7sePxNzPxzDcAz1NUYkmqLHcysTxT3vKSmBFdbhxquAxVtAvFJsR4LA8O1GQLfve5MBRW2WNiAGo3t_SPfJgURA5G1CzDqguLmOyO3ix-cqogRSetfTmNVkT2_eoXum_N671dXOsXSTJ6__XdB95VGOAWLZUlN4lFj56KKhmlfFnKLI49OosF-puIEqYiapSiSmOjXBWXeB1VOH5E9TLKnSUiJoT_SyIrAih8FpNeC6AZH6rXonaOuUAt0SXsRKkcNqg4QugvOfKREjzbVIpnLN2zAZt_ndoGZTi68T9_xptwvTPB2dt2z9yCLV_fhittUc7VHfhIoS-zFXMhYsWzamZOEPQCqTV2WxwiAjdsinsWzXTHKD-HhdMv9sUb1n4xRvkAP5q78O1CJnIPtut57R8Aw6fYUuZR7C1azVVpZC7SSthCGqHQ6htA3C-5th0dO1UFmekQFpBK3YqJRjHRQUw09nm57rNoyUjObb3Ti4DugKnRp-s_gGfr2wgpdE5kaj8_xjZ5oVKZKBrk_Vbw1q8LBJFo9Q9AbIjkugHRlW_eqaeHgbZcCnRtI3zmq154T4f171k8PH8WT-Eqyq_-tDfefwTXEspNCSH1O7C9PDr2j-GyPVlOm6MnYXcy-H7RcvwHB3l23A
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Highly+diverse+flavobacterial+phages+isolated+from+North+Sea+spring+blooms&rft.jtitle=The+ISME+Journal&rft.au=Bartlau%2C+Nina&rft.au=Wichels%2C+Antje&rft.au=Krohne%2C+Georg&rft.au=Adriaenssens%2C+Evelien+M&rft.date=2022-02-01&rft.issn=1751-7370&rft.eissn=1751-7370&rft.volume=16&rft.issue=2&rft.spage=555&rft_id=info:doi/10.1038%2Fs41396-021-01097-4&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1751-7362&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1751-7362&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1751-7362&client=summon