CScape: a tool for predicting oncogenic single-point mutations in the cancer genome

For somatic point mutations in coding and non-coding regions of the genome, we propose CScape , an integrative classifier for predicting the likelihood that mutations are cancer drivers. Tested on somatic mutations, CScape tends to outperform alternative methods, reaching 91% balanced accuracy in co...

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Bibliographic Details
Published in:Scientific reports Vol. 7; no. 1; pp. 11597 - 10
Main Authors: Rogers, Mark F., Shihab, Hashem A., Gaunt, Tom R., Campbell, Colin
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 14.09.2017
Nature Publishing Group
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ISSN:2045-2322, 2045-2322
Online Access:Get full text
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