Function and therapeutic value of astrocytes in neurological diseases

Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse functions in health and disease. Astrocyte dysfunction is found in numerous diseases, including multiple sclerosis, Alzheimer disease, Parkinson disease, Huntington disease and neuropsychiatric disorders. As...

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Veröffentlicht in:	Nature reviews. Drug discovery Jg. 21; H. 5; S. 339 - 358
Hauptverfasser:	Lee, Hong-Gyun, Wheeler, Michael A, Quintana, Francisco J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Nature Publishing Group 01.05.2022
Schlagworte:	Astrocytes - metabolism Cell Communication Cytokines DNA methylation Epigenetics Glutamic Acid - metabolism Homeostasis Humans Huntingtons disease Inflammation Metabolism Morphology Multiple Sclerosis Nervous system Nervous System Diseases - metabolism Nervous System Diseases - therapy Neurodegeneration Neurons Parkinson's disease Pathogenesis Permeability
ISSN:	1474-1776, 1474-1784, 1474-1784
Online-Zugang:	Volltext
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