An Integrative Analysis of Tumor Proteomic and Phosphoproteomic Profiles to Examine the Relationships Between Kinase Activity and Phosphorylation

Phosphorylation of proteins is a key way cells regulate function, both at the individual protein level and at the level of signaling pathways. Kinases are responsible for phosphorylation of substrates, generally on serine, threonine, or tyrosine residues. Though particular sequence patterns can be i...

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Veröffentlicht in:	Molecular & cellular proteomics Jg. 18; H. 8 suppl 1; S. S26
Hauptverfasser:	Arshad, Osama A, Danna, Vincent, Petyuk, Vladislav A, Piehowski, Paul D, Liu, Tao, Rodland, Karin D, McDermott, Jason E
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 09.08.2019
Schlagworte:	Humans Neoplasms - metabolism Phosphoproteins - metabolism Phosphorylation Protein Kinases - metabolism Proteomics Phosphorylation Computational Biology iTRAQ Breast cancer Cancer Biology Phosphoproteome Ovarian cancer
ISSN:	1535-9484, 1535-9484
Online-Zugang:	Weitere Angaben
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