Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination: a randomized phase 4 trial

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and the waning of vaccine-elicited neutralizing antibodies suggests that additional coronavirus disease 2019 (COVID-19) vaccine doses may be needed for individuals who initially received CoronaVac. We evaluated th...

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Bibliographic Details
Published in:	Nature medicine Vol. 28; no. 2; pp. 401 - 409
Main Authors:	Li, Jingxin, Hou, Lihua, Guo, Xiling, Jin, Pengfei, Wu, Shipo, Zhu, Jiahong, Pan, Hongxing, Wang, Xue, Song, Zhizhou, Wan, Jingxuan, Cui, Lunbiao, Li, Junqiang, Chen, Yin, Wang, Xuewen, Jin, Lairun, Liu, Jingxian, Shi, Fengjuan, Xu, Xiaoyu, Zhu, Tao, Chen, Wei, Zhu, Fengcai
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.02.2022 Nature Publishing Group
Subjects:	631/250/2152/2153/1291 631/250/590/1883 692/308/2779/109/1943 Adenoviridae - immunology Adenoviruses Adolescent Adult Adults Antibodies Antibodies, Neutralizing - blood Antibodies, Viral - blood Biomedical and Life Sciences Biomedicine Cancer Research China Coronaviruses COVID-19 COVID-19 - immunology COVID-19 - prevention & control COVID-19 vaccines COVID-19 Vaccines - adverse effects COVID-19 Vaccines - immunology Female Homology Humans Immunization Immunization, Secondary Immunogenicity Immunogenicity, Vaccine - immunology Immunoglobulin G - blood Infectious Diseases Injection Site Reaction - pathology Male Metabolic Diseases Middle Aged Molecular Medicine Neurosciences Neutralizing SARS-CoV-2 - immunology Severe acute respiratory syndrome coronavirus 2 Side effects T-Lymphocytes - immunology Vaccination Vaccines Vaccines, Inactivated - immunology Viral diseases Young Adult China
ISSN:	1078-8956, 1546-170X, 1546-170X
Online Access:	Get full text
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