Effects of Apolipoprotein E polymorphism on carotid intima-media thickness, incident myocardial infarction and incident stroke

The Apolipoprotein E (APOE) gene polymorphism (rs429358 and rs7412) shows a well-established association with lipid profiles, but its effect on cardiovascular disease is still conflicting. Therefore, we examined the association of different APOE alleles with common carotid artery intima-media thickn...

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Bibliographic Details
Published in:	Scientific reports Vol. 12; no. 1; pp. 5142 - 10
Main Authors:	Pitchika, Anitha, Markus, Marcello Ricardo Paulista, Schipf, Sabine, Teumer, Alexander, Van der Auwera, Sandra, Nauck, Matthias, Dörr, Marcus, Felix, Stephan, Grabe, Hans-Jörgen, Völzke, Henry, Ittermann, Till
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 24.03.2022 Nature Publishing Group Nature Portfolio
Subjects:	692/4019 692/499 Alleles Apolipoprotein E4 Apolipoproteins Apolipoproteins E - genetics Cardiovascular diseases Carotid artery Carotid Intima-Media Thickness Cerebral infarction Gene polymorphism Heart attacks Homozygotes Humanities and Social Sciences Humans multidisciplinary Myocardial infarction Myocardial Infarction - epidemiology Myocardial Infarction - genetics Plaque, Atherosclerotic Plaques Polymorphism Polymorphism, Genetic Population studies Regression analysis Risk Factors Science Science (multidisciplinary) Stroke Stroke - epidemiology Stroke - genetics
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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