Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients

Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed to assess whether CP administered during the first week of symptoms reduced the disease progression or risk of hospitalization of outpatients. Two multicenter, double-blind randomized trials (NCT04621123, NCT0458...

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Bibliographic Details
Published in:	Nature communications Vol. 13; no. 1; pp. 2583 - 9
Main Authors:	Millat-Martinez, Pere, Gharbharan, Arvind, Alemany, Andrea, Rokx, Casper, Geurtsvankessel, Corine, Papageorgiou, Grigorios, van Geloven, Nan, Jordans, Carlijn, Groeneveld, Geert, Swaneveld, Francis, van der Schoot, Ellen, Corbacho-Monné, Marc, Ouchi, Dan, Piccolo Ferreira, Francini, Malchair, Pierre, Videla, Sebastian, García García, Vanesa, Ruiz-Comellas, Anna, Ramírez-Morros, Anna, Rodriguez Codina, Joana, Amado Simon, Rosa, Grifols, Joan-Ramon, Blanco, Julian, Blanco, Ignacio, Ara, Jordi, Bassat, Quique, Clotet, Bonaventura, Baro, Bàrbara, Troxel, Andrea, Zwaginga, Jaap Jan, Mitjà, Oriol, Rijnders, Bart J. A.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 11.05.2022 Nature Publishing Group Nature Portfolio
Subjects:	631/326/596/4130 692/308/2779/777 692/699/255/2514 Bayes Theorem Bayesian analysis Clinical trials Coronaviruses COVID-19 COVID-19 - therapy COVID-19 Serotherapy Data analysis Death Fatalities Hospitalization Humanities and Social Sciences Humans IgG antibody Immunization, Passive Immunoglobulin G Mechanical ventilation Meta-analysis Middle Aged Mortality Multicenter Studies as Topic multidisciplinary Outpatients Patients Plasma Randomized Controlled Trials as Topic SARS-CoV-2 Science Science (multidisciplinary) Signs and symptoms Treatment Outcome
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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