Gene Expression Predicts Histological Severity and Reveals Distinct Molecular Profiles of Nonalcoholic Fatty Liver Disease

The heterogeneity of biological processes driving the severity of nonalcoholic fatty liver disease (NAFLD) as reflected in the transcriptome and the relationship between the pathways involved are not well established. Well-defined associations between gene expression profiles and disease progression...

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Bibliographic Details
Published in:	Scientific reports Vol. 9; no. 1; pp. 12541 - 14
Main Authors:	Hoang, Stephen A., Oseini, Abdul, Feaver, Ryan E., Cole, Banumathi K., Asgharpour, Amon, Vincent, Robert, Siddiqui, Mohammad, Lawson, Mark J., Day, Nathan C., Taylor, Justin M., Wamhoff, Brian R., Mirshahi, Faridoddin, Contos, Melissa J., Idowu, Michael, Sanyal, Arun J.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 29.08.2019 Nature Publishing Group
Subjects:	38/39 38/91 631/114/2401 692/4020/4021/1607/2750 Cohort Studies Disease Progression Fatty liver Gene expression Gene Expression Profiling Heterogeneity Histology Humanities and Social Sciences Humans Liver - metabolism Liver diseases multidisciplinary Non-alcoholic Fatty Liver Disease - genetics Non-alcoholic Fatty Liver Disease - metabolism Non-alcoholic Fatty Liver Disease - pathology Protein interaction Proteins - genetics Proteins - metabolism Science Science (multidisciplinary) Transcriptome
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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