Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model

Antimicrobial resistance in Neisseria gonorrhoeae is threatening the treatment and control of gonorrhea globally, and new treatment options are imperative. Utilizing our dynamic in vitro hollow fiber infection model (HFIM), we examined the pharmacodynamics of the first-in-class spiropyrimidinetrione...

Celý popis

Podrobná bibliografia

Vydané v:	Frontiers in pharmacology Ročník 12; s. 682135
Hlavní autori:	Jacobsson, Susanne, Golparian, Daniel, Oxelbark, Joakim, Alirol, Emilie, Franceschi, Francois, Gustafsson, Tomas N., Brown, David, Louie, Arnold, Drusano, George, Unemo, Magnus
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland Frontiers Media S.A 21.05.2021
Predmet:	antimicrobial treatment hollow fiber infection model Neisseria gonorrhoeae pharmacodynamics pharmacokinetics Pharmacology zoliflodacin pharmacokinetics hollow fiber infection model Neisseria gonorrhoeae zoliflodacin pharmacodynamics antimicrobial treatment
ISSN:	1663-9812, 1663-9812
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!