The Anti-Inflammatory Potential of Tricyclic Antidepressants (TCAs): A Novel Therapeutic Approach to Atherosclerosis Pathophysiology

Atherosclerosis, a chronic inflammatory disease, is driven by complex molecular mechanisms involving inflammatory cytokines and immune pathways. According to recent research, tricyclic antidepressants (TCAs), which are typically prescribed to treat depressive disorders, have strong anti-inflammatory...

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Bibliographic Details
Published in:	Pharmaceuticals (Basel, Switzerland) Vol. 18; no. 2; p. 197
Main Authors:	Eslami, Majid, Monemi, Marzieh, Nazari, Mohammad Ali, Azami, Mohammad Hossein, Shariat Rad, Parand, Oksenych, Valentyn, Naderian, Ramtin
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01.02.2025 MDPI
Subjects:	Adrenergic receptors Analgesics Anticholinergics Antidepressants Antidepressants, Tricyclic Atherosclerosis Cardiovascular disease cytokine Cytokines Depression, Mental Drug therapy Health aspects Histamine inflammasome Inflammation Inflammatory diseases Interleukins Ischemia Mental depression Neurotransmitters Older people Pain Pathophysiology Physiological aspects Review Serotonin Side effects Testing tricyclic antidepressants (TCAs) Tumor necrosis factor Iran atherosclerosis cytokine tricyclic antidepressants (TCAs) inflammasome pathophysiology
ISSN:	1424-8247, 1424-8247
Online Access:	Get full text
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