The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians

Metabolic traits are heritable phenotypes widely-used in assessing the risk of various diseases. We conduct a genome-wide association analysis (GWAS) of nine metabolic traits (including glycemic, lipid, liver enzyme levels) in 125,872 Korean subjects genotyped with the Korea Biobank Array. Following...

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Veröffentlicht in:	Nature communications Jg. 13; H. 1; S. 6642 - 13
Hauptverfasser:	Kim, Young Jin, Moon, Sanghoon, Hwang, Mi Yeong, Han, Sohee, Jang, Hye-Mi, Kong, Jinhwa, Shin, Dong Mun, Yoon, Kyungheon, Kim, Sung Min, Lee, Jong-Eun, Mahajan, Anubha, Park, Hyun-Young, McCarthy, Mark I., Cho, Yoon Shin, Kim, Bong-Jo
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 04.11.2022 Nature Publishing Group Nature Portfolio
Schlagworte:	45 45/23 45/43 49 49/61 631/208/205/2138 631/208/457/649/2219 692/53 692/699/2743 Asian People - genetics Association analysis Biobanks Blood Glucose - genetics Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - genetics Genetic diversity Genetic Predisposition to Disease Genetic variance Genetic Variation Genome-Wide Association Study Genomes Health risk assessment Health risks Humanities and Social Sciences Humans Lipids Meta-analysis Metabolism multidisciplinary Phenotype Phenotypes Polygenic inheritance Polymorphism, Single Nucleotide Predictions Risk assessment Science Science (multidisciplinary)
ISSN:	2041-1723, 2041-1723
Online-Zugang:	Volltext
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