Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic disorder characterized by disabling fatigue. Several studies have sought to identify diagnostic biomarkers, with varying results. Here, we innovate this process by combining both mRNA expression and DNA methylation data. We per...

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Bibliographic Details
Published in:	Scientific reports Vol. 11; no. 1; pp. 4541 - 11
Main Authors:	Metselaar, Paula I., Mendoza-Maldonado, Lucero, Li Yim, Andrew Yung Fong, Abarkan, Ilias, Henneman, Peter, te Velde, Anje A., Schönhuth, Alexander, Bosch, Jos A., Kraneveld, Aletta D., Lopez-Rincon, Alejandro
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 25.02.2021 Nature Publishing Group Nature Portfolio
Subjects:	631/114/1305 692/308/2056 692/53/2421 Chronic fatigue syndrome Deoxyribonucleic acid DNA DNA methylation Encephalomyelitis Fatigue Gene expression Humanities and Social Sciences Immune system Leukocytes (mononuclear) multidisciplinary Peripheral blood mononuclear cells Science Science (multidisciplinary)
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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