Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers

Exercise training positively affects metabolic health through increased mitochondrial oxidative capacity and improved glucose regulation and is the first line of treatment in several metabolic diseases. However, the upper limit of the amount of exercise associated with beneficial therapeutic effects...

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Bibliographic Details
Published in:	Cell metabolism Vol. 33; no. 5; p. 957
Main Authors:	Flockhart, Mikael, Nilsson, Lina C, Tais, Senna, Ekblom, Björn, Apró, William, Larsen, Filip J
Format:	Journal Article
Language:	English
Published:	United States 04.05.2021
Subjects:	Blood Glucose - analysis Catalase - metabolism Glucose Tolerance Test Glucose Transporter Type 4 - metabolism Glycogen - metabolism Healthy Volunteers Humans Hydrogen Peroxide - metabolism Mitochondria - metabolism Muscle, Skeletal - metabolism Muscle, Skeletal - pathology NF-E2-Related Factor 2 - metabolism Oxidative Stress Physical Endurance Superoxide Dismutase - metabolism high-intensity interval training mitochondria metabolic dysfunction exercise adaptations exercise athletes mitochondrial dysfunction continuous glucose monitoring glucose tolerance insulin resistance mitochondrial dynamics
ISSN:	1932-7420, 1932-7420
Online Access:	Get more information
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