Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability

Hippocampal CA2 pyramidal cells project into both the neighboring CA1 and CA3 subfields, leaving them well positioned to influence network physiology and information processing for memory and space. While recent work has suggested unique roles for CA2, including encoding position during immobility a...

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Bibliographic Details
Published in:	Neuron (Cambridge, Mass.) Vol. 94; no. 3; p. 642
Main Authors:	Boehringer, Roman, Polygalov, Denis, Huang, Arthur J Y, Middleton, Steven J, Robert, Vincent, Wintzer, Marie E, Piskorowski, Rebecca A, Chevaleyre, Vivien, McHugh, Thomas J
Format:	Journal Article
Language:	English
Published:	United States 03.05.2017
Subjects:	Animals CA2 Region, Hippocampal - cytology CA2 Region, Hippocampal - physiology CA3 Region, Hippocampal - cytology CA3 Region, Hippocampal - physiology Hippocampus - physiology Metalloendopeptidases - genetics Metalloendopeptidases - metabolism Mice Nerve Net - physiology Neural Inhibition - physiology Pyramidal Cells - physiology Synaptic Transmission - physiology Tetanus Toxin - genetics Tetanus Toxin - metabolism Theta Rhythm - physiology theta oscillation CA3 hippocampus ripple CA2 spatial coding DREADD tetanus toxin place cell
ISSN:	1097-4199, 1097-4199
Online Access:	Get more information
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