Molecular basis for intestinal mucin recognition by galectin-3 and C-type lectins

Intestinal mucins trigger immune responses upon recognition by dendritic cells via protein-carbohydrate interactions. We used a combination of structural, biochemical, biophysical, and cell-based approaches to decipher the specificity of the interaction between mucin glycans and mammalian lectins ex...

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Vydáno v:	The FASEB journal Ročník 32; číslo 6; s. 3301
Hlavní autoři:	Leclaire, Charlotte, Lecointe, Karine, Gunning, Patrick A, Tribolo, Sandra, Kavanaugh, Devon W, Wittmann, Alexandra, Latousakis, Dimitrios, MacKenzie, Donald A, Kawasaki, Norihito, Juge, Nathalie
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.06.2018
Témata:	Animals Blood Proteins Cell Adhesion Molecules - chemistry Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Galectin 3 - chemistry Galectin 3 - genetics Galectin 3 - metabolism Galectins Humans Lectins, C-Type - chemistry Lectins, C-Type - genetics Lectins, C-Type - metabolism Mass Spectrometry Mice Mucin-2 - chemistry Mucin-2 - genetics Mucin-2 - metabolism Protein Domains Receptors, Cell Surface - chemistry Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Structure-Activity Relationship immune system O-glycosylation N-glycosylation mucus
ISSN:	1530-6860, 1530-6860
On-line přístup:	Zjistit podrobnosti o přístupu
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