Biology and therapy of inherited retinal degenerative disease: insights from mouse models

Retinal neurodegeneration associated with the dysfunction or death of photoreceptors is a major cause of incurable vision loss. Tremendous progress has been made over the last two decades in discovering genes and genetic defects that lead to retinal diseases. The primary focus has now shifted to unc...

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Bibliographic Details
Published in:	Disease models & mechanisms Vol. 8; no. 2; pp. 109 - 129
Main Authors:	Veleri, Shobi, Lazar, Csilla H., Chang, Bo, Sieving, Paul A., Banin, Eyal, Swaroop, Anand
Format:	Journal Article
Language:	English
Published:	England The Company of Biologists Ltd 01.02.2015 The Company of Biologists Limited The Company of Biologists
Subjects:	Animals Disease Disease Models, Animal Genes Genetic Diseases, Inborn - therapy Humans Light Signal Transduction Macular degeneration Mice Mouse mutants Mutation Photoreceptor Photoreceptor Cells, Vertebrate - pathology Photoreceptors Proteins Retina Retina - pathology Retina - physiopathology Retinal Degeneration - therapy Retinal development Retinal disease Review Retinal development Mouse mutants Retinal disease Photoreceptor
ISSN:	1754-8403, 1754-8411, 1754-8411
Online Access:	Get full text
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