Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment

Immunotherapy has gained increasing focus in treating pancreatic ductal adenocarcinoma (PDAC), since conventional therapies like chemotherapy could not provide satisfactory improvement in overall survival outcome of PDAC patients. However, it is still not the game changing solution due to the unique...

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Vydáno v:	Biomaterials Ročník 268; s. 120546
Hlavní autoři:	Zhou, Wenxi, Zhou, Yu, Chen, Xinli, Ning, Tingting, Chen, Hongyi, Guo, Qin, Zhang, Yiwen, Liu, Peixin, Zhang, Yujie, Li, Chao, Chu, Yongchao, Sun, Tao, Jiang, Chen
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier Ltd 01.01.2021
Témata:	adenocarcinoma biocompatible materials BM-MSC exosomes bone marrow cancer therapy cell death cytotoxicity drug therapy drugs exosomes Galectin 9/dectin 1 axis galectins Immunogenic cell death immunogenicity immunosuppression immunotherapy Macrophage polarization macrophages mesenchymal stromal cells Pancreatic cancer immunotherapy Galectin 9/dectin 1 axis Macrophage polarization Pancreatic cancer immunotherapy Immunogenic cell death BM-MSC exosomes
ISSN:	0142-9612, 1878-5905, 1878-5905
On-line přístup:	Získat plný text
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