Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment

Immunotherapy has gained increasing focus in treating pancreatic ductal adenocarcinoma (PDAC), since conventional therapies like chemotherapy could not provide satisfactory improvement in overall survival outcome of PDAC patients. However, it is still not the game changing solution due to the unique...

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Bibliographic Details
Published in:	Biomaterials Vol. 268; p. 120546
Main Authors:	Zhou, Wenxi, Zhou, Yu, Chen, Xinli, Ning, Tingting, Chen, Hongyi, Guo, Qin, Zhang, Yiwen, Liu, Peixin, Zhang, Yujie, Li, Chao, Chu, Yongchao, Sun, Tao, Jiang, Chen
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.01.2021
Subjects:	adenocarcinoma biocompatible materials BM-MSC exosomes bone marrow cancer therapy cell death cytotoxicity drug therapy drugs exosomes Galectin 9/dectin 1 axis galectins Immunogenic cell death immunogenicity immunosuppression immunotherapy Macrophage polarization macrophages mesenchymal stromal cells Pancreatic cancer immunotherapy Galectin 9/dectin 1 axis Macrophage polarization Pancreatic cancer immunotherapy Immunogenic cell death BM-MSC exosomes
ISSN:	0142-9612, 1878-5905, 1878-5905
Online Access:	Get full text
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