Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study

N-acetyltransferases (NAT) 1 and 2 are polymorphic enzymes catalyzing the metabolic activation of heterocyclic amines. We investigated the modifying effects of NAT1 and NAT2 polymorphisms on the association of meat consumption, heterocyclic amine intake, and smoking with colorectal cancer risk. In t...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention Jg. 18; H. 7; S. 2098
Hauptverfasser:	Nöthlings, Ute, Yamamoto, Jennifer F, Wilkens, Lynne R, Murphy, Suzanne P, Park, Song-Yi, Henderson, Brian E, Kolonel, Laurence N, Le Marchand, Loïc
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.2009
Schlagworte:	Aged Arylamine N-Acetyltransferase - genetics Arylamine N-Acetyltransferase - metabolism Case-Control Studies Cohort Studies Colorectal Neoplasms - epidemiology Colorectal Neoplasms - genetics Diet Female Hawaii - epidemiology Heterocyclic Compounds - adverse effects Heterocyclic Compounds - metabolism Humans Isoenzymes - genetics Logistic Models Los Angeles - epidemiology Male Meat Middle Aged Polymorphism, Single Nucleotide Racial Groups Risk Factors Smoking - adverse effects Surveys and Questionnaires Hawaii Los Angeles
ISSN:	1538-7755, 1538-7755
Online-Zugang:	Weitere Angaben
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