Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin

Fish oil has been broadly reported as a potential supplement to ameliorate the severity of some skin disorders such as photoaging, skin cancer, allergy, dermatitis, cutaneous wounds, and melanogenesis. There has been increasing interest in the relationship of fish oil with skin protection and homeos...

Full description

Saved in:
Bibliographic Details
Published in:Marine drugs Vol. 16; no. 8; p. 256
Main Authors: Huang, Tse-Hung, Wang, Pei-Wen, Yang, Shih-Chun, Chou, Wei-Ling, Fang, Jia-You
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 30.07.2018
MDPI
Subjects:
Administration, Cutaneous
Allergies
Animal models
Animals
Arachidonic acid
Cancer
Cosmetics - pharmacology
Cosmetics - therapeutic use
cosmetology
Cytokines
Data processing
Dermatitis
dermatology
Dietary Supplements
Disorders
Docosahexaenoic acid
Eicosapentaenoic acid
Fatty acids
Fatty Acids - pharmacology
Fatty Acids - therapeutic use
Fish
fish oil
Fish oils
Fish Oils - chemistry
Fish Oils - pharmacology
Fish Oils - therapeutic use
Fish skin
Fishes
Homeostasis
Humans
Inflammation
Linoleic acid
Linolenic acid
Lipid Metabolism - drug effects
Oil
Oils & fats
omega-3
polyunsaturated fatty acid
Polyunsaturated fatty acids
Regulators
Review
skin
Skin - drug effects
Skin Aging - drug effects
Skin Aging - radiation effects
Skin cancer
Skin diseases
Skin Diseases - drug therapy
Skin Diseases - prevention & control
Supplements
Therapeutic applications
Ultraviolet Rays - adverse effects
Wound healing
skin
cosmetology
dermatology
omega-3
polyunsaturated fatty acid
fish oil
ISSN:1660-3397, 1660-3397
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fish oil has been broadly reported as a potential supplement to ameliorate the severity of some skin disorders such as photoaging, skin cancer, allergy, dermatitis, cutaneous wounds, and melanogenesis. There has been increasing interest in the relationship of fish oil with skin protection and homeostasis, especially with respect to the omega-3 polyunsaturated fatty acids (PUFAs), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA). The other PUFAs, such as α-linolenic acid (ALA) and linoleic acid (LA), also show a beneficial effect on the skin. The major mechanisms of PUFAs for attenuating cutaneous inflammation are the competition with the inflammatory arachidonic acid and the inhibition of proinflammatory eicosanoid production. On the other hand, PUFAs in fish oil can be the regulators that affect the synthesis and activity of cytokines for promoting wound healing. A systemic review was conducted to demonstrate the association between fish oil supplementation and the benefits to the skin. The following describes the different cosmetic and therapeutic approaches using fatty acids derived from fish oil, especially ALA, LA, DHA, and EPA. This review summarizes the cutaneous application of fish oil and the related fatty acids in the cell-based, animal-based, and clinical models. The research data relating to fish oil treatment of skin disorders suggest a way forward for generating advances in cosmetic and dermatological uses.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
These authors contributed equally to this work.
ISSN:1660-3397
1660-3397
DOI:10.3390/md16080256